Metabolism Current Events | Metabolism News | 8
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'Best of both worlds' — Targeting a single gene could inhibit bone decay and stimulate bone growth
Researchers at the University of Pennsylvania's School of Medicine have found by targeting the function of a single gene that it is possible to inhibit bone decay while simultaneously stimulating bone formation. view more (2006-12-11)
Gene mutation responsible for premature skin aging disease identified
In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome." view more (2009-09-01)
Frequent hemodialysis at night may improve some outcomes for patients with end-stage kidney disease
Patients who received hemodialysis at night six times a week for treatment of end-stage kidney disease had improvements on certain outcomes, including reduced need for blood pressure medications and improvement in selected quality of life measures, compared to patients who received conventional hemodialysis three times weekly. view more (2007-09-19)
Bug guts map brings scientists closer to understanding different bugs' role in the body
Scientists have made a major step towards understanding precisely which bugs in the gut are involved in which processes in the body, by mapping the different species of bugs living in seven members of the same Chinese family. view more (2008-02-06)
Cancer-causing gut bacteria exposed
Normal gut bacteria are thought to be involved in colon cancer but the exact mechanisms have remained unknown. Now, scientists from the USA have discovered that a molecule produced by a common gut bacterium activates signalling pathways that are associated with cancer cells. view more (2008-09-22)
URI nutritionist finds chewing gum can reduce calorie intake, increase energy expenditure
A nutrition professor at the University of Rhode Island studying the effects of chewing sugar-free gum on weight management has found that it can help to reduce calorie intake and increase energy expenditure. view more (2009-10-28)
Unusual three-drug combo inhibits growth of aggressive tumors
An experimental anti-cancer regimen combined a diuretic, a Parkinson's disease medication and a drug ordinarily used to reverse the effect of sedatives. view more (2006-09-08)
New insight into sudden infant death syndrome
Sudden infant death syndrome (SIDS) usually affects infants during their first six months of life. The incidence of this disease in Sweden increased during the 1980's and was approximately one death in 1000 live births in 1990 and was considerably greater in some other countries. After 1992-1993 the incidence of this disease has decreased to a... view more... (2001-12-20)
Cellular fuel gauge could hold clue to diabetes - exercise link.
A molecule in the body could hold the key to explaining why people who exercise regularly are less likely to have illnesses such as type 2 diabetes. The enzyme, called AMPK, acts as the body's 'fuel gauge,' playing a crucial role in regulating energy intake, utilisation and storage. Finding out exactly how it works could help to explain how... view more... (2005-01-17)
Bugs in the gut could play key role in understanding human disease and drug toxicity
Understanding how microbes in the gut interact with the body could lead scientists and doctors to new a understanding and novel treatments for diseases say scientists from Imperial College London and Astra Zeneca. view more (2004-10-05)
Iron is involved in prion disease-associated neuronal demise
Imbalance of iron homeostasis is a common feature of prion disease-affected human, mouse, and hamster brains, according to a new study by Dr. Neena Singh and colleagues at Case Western Reserve University School of Medicine, alongside collaborators from Creighton University. view more (2009-03-16)
Study associates 11 new gene sites with cholesterol, triglyceride levels
An international research team has identified 11 novel locations in the human genome where common variations appear to influence cholesterol or triglyceride levels, bringing the total number of lipid-associated genes to 30. view more (2008-12-08)
They're alive!! Megacities breathe, consume energy, excrete wastes and pollute
A scientific trend to view the world's biggest cities as analogous to living, breathing organisms is fostering a deep new understanding of how poor air quality in megacities can harm residents, people living far downwind, and also play a major role in global climate change. view more (2009-08-18)
Europe's most common genetic disease is a liver disorder
Much less widely known than the dangerous consequences of iron deficiencies is the fact that too much iron can also cause problems. The exact origin of the genetic iron overload disorder hereditary hemochromatosis [HH] has remained elusive. view more (2008-02-07)
Existing anti-obesity drugs may be effective against flu, hepatitis and HIV
Viruses dramatically increase cellular metabolism, and existing anti-obesity drugs may represent a new way to block these metabolic changes and inhibit viral infection, according to a study published today in the journal Nature Biotechnology. view more (2008-09-29)
Obesity chokes up the cellular power plant
The machinery responsible for energy production in fat cells is working poorly as a result of obesity. Finnish research done at the University of Helsinki and the National Public Health Institute shows that this may aggravate and work to maintain the obese state in humans. view more (2008-03-13)
Everybody dance: The energy you use won't shorten your life
The theory that animals die when they've expended their lifetime allotment of energy may be reaching the end of its own life, according to a study presented at The American Physiological Society conference, Comparative Physiology 2006. view more (2006-10-09)
Evolution of human genome's 'guardian' gives people unique protections from DNA damage
Human evolution has created enhancements in key genes connected to the p53 regulatory network - the so-called guardian of the genome - by creating additional safeguards in human genes to boost the network's ability to guard against DNA damage that could cause cancer or a variety of genetic diseases. view more (2008-01-17)
Adaptive functional evolution of leptin in cold-adaptive pika family
Researchers at the Northwest Institute of Plateau Biology, Chinese Academy of Sciences have put forward the viewpoint for the first time that adaptive functional evolution may occur in the leptin protein of the pika (Ochotona) family, a typical cold-adaptive mammal. view more (2008-01-23)
Fatty acid catabolism higher due to polyphenol intake
Polyphenols, dietary substances from vegetables, fruits and green tea, bring about a change in the energy metabolism. Dutch researcher Vincent de Boer has discovered that polyphenols increase the fatty acid breakdown in rats and influence the glucose use in fat cells. view more (2007-05-15)
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