Metabolism Current Events | Metabolism News | 9
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Sewer-gas-induced suspended animation is rapid and reversible
Low doses of the toxic gas responsible for the unpleasant odor of rotten eggs can safely and reversibly depress both metabolism and aspects of cardiovascular function in mice, producing a suspended-animation-like state. view more (2008-03-25)
Caltech researchers pinpoint neurons that control obesity in fruit flies
A team of scientists from the California Institute of Technology (Caltech) have pinpointed two groups of neurons in fruit fly brains that have the ability to sense and manipulate the fly's fat stores in much the same way as do neurons in the mammalian brain. view more (2009-08-19)
Researchers identify proteins involved in new neurodegenerative syndrome
The interplay of two proteins that bind to messenger RNA, a molecule that mediates translation of the information encoded in genes into proteins, triggers the appearance of fragile X-associated tremor/ataxia syndrome (FTAX), a late-life disorder associated with the gene that causes fragile X syndrome in children. view more (2007-08-16)
Exploiting Nature's Weapons in the Fight Against Diabetes
Scientists at the University of Ulster are harnessing molecules produced naturally in the body to tackle one of the world's major health problems - diabetes. Their novel approach involves bioengineering gut peptides - molecules produced in the human intestine and released in response to feeding - to prolong their duration of action and,... view more... (2004-03-23)
Marathon mice elucidate little-known muscle type
Researchers report in the January issue of the journal Cell Metabolism, published by Cell Press, the discovery of a genetic "switch" that drives the formation of a poorly understood type of muscle. Moreover, they found, animals whose muscles were full of the so-called IIX fibers were able to run farther and at higher work loads than... view more... (2007-01-03)
Biofuel cells without the bio cells
Proteins keep cells humming. Some are enzymes that taxi electrons to chemicals outside the cell, to discharge excess energy generated during metabolism. This maintains energy flow in the cell and, in turn, keeps the cell alive. view more (2006-10-18)
Anti-malarial drug may reduce risk of diabetes for patients with rheumatoid arthritis
Preliminary research suggests that use of the anti-malarial drug hydroxychloroquine may help reduce the risk of the development of diabetes in patients with rheumatoid arthritis view more (2007-07-11)
University of Pittsburgh researchers crack code of 3-D structure in key metabolic protein
Using X-ray crystallography, researchers at the University of Pittsburgh School of Medicine led by structural biologist Joanne I. Yeh, Ph.D., have become the first to decipher the three-dimensional structure of a membrane-bound enzyme that plays a crucial role in glycerol metabolism - a discovery that could lead to important advances against... view more... (2008-03-11)
URI scientists reveal mechanism that regulates cancer-causing gene
Two University of Rhode Island scientists have revealed how a cancer causing protein is regulated by reactive oxygen species (ROS) -- a type of stress signal. Their findings provide new insight into how this protein normally behaves in human cells and may help in the design of drugs targeting specific cancers. view more (2009-03-27)
Life at the jolt
Researchers at the Biodesign Institute are using the tiniest organisms on the planet 'bacteria' as a viable option to make electricity. In a new study featured in the journal Biotechnology and Bioengineering, lead author Andrew Kato Marcus and colleagues Cesar Torres and Bruce Rittmann have gained critical insights that may lead to... view more... (2008-01-03)
Ketogenic diet prevents seizures by enhancing brain energy production, increasing neuron stability
Although the high-fat, calorie-restricted ketogenic diet (KD) has long been used to prevent childhood epileptic seizures that are unresponsive to drugs, physicians have not really understood exactly why the diet works. view more (2005-11-14)
Alcohol consumption and polymorphisms of cytochromes P4502E1 are high risks for ESCC
Heavier alcohol consumption increases the risk of ESCC. There are synergetic interactions among alcohol drinking and ALDH2, ADH1B, CYP2E1 genotypes. view more (2008-03-13)
Forsyth scientists find linkages between serotonin reuptake inhibitors and bone mass
Scientists at The Forsyth Institute have found that fluoxetine (Prozac), a drug used in the treatment of depression and obsessive-compulsive disorders, increases bone mass. view more (2006-10-13)
A genome wide search for genes underlying anxiety disorders turned up unexpected candidates
Increasing the activity of two enzymes better known for their role in oxidative stress metabolism turns normally relaxed mice into "Nervous Nellies," according to research conducted at the Salk Institute for Biological Studies and reported in the early online edition of Nature. view more (2005-10-31)
Feeling sleepy is all in your genes
Genes responsible for our 24 hour body clock influence not only the timing of sleep, but also appear to be central to the actual restorative process of sleep, according to research published in the online open access journal BMC Neuroscience. view more (2007-10-18)
A new weapon in the fight against obesity and diabetes
A study appearing November 5 in the journal Cell Metabolism demonstrates that a synthetic new chemical entity protects against diet-induced obesity, improves glucose tolerance and insulin sensitivity and enhances exercise endurance by enhancing fat utilization in certain target tissues. view more (2008-11-05)
HIV infection appears to increases the risk of heart attack
Researchers from Massachusetts General Hospital (MGH) have found that infection with HIV, the virus that causes AIDS, is also associated with increased risk of myocardial infarction or heart attack. view more (2007-04-25)
Vitamin D may exacerbate autoimmune disease
Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease. view more (2009-04-09)
New chimeric mouse model for human liver diseases, drug testing
Cells cultured in the lab are like a fish out of water. Often, their behavior does not reflect their biological function within an entire organ or organism, which, for example, turns studying human liver cells into a big challenge. view more (2007-12-04)
Abnormal fat metabolism underlies heart problems in diabetic patients
Heart disease hits people with diabetes twice as often as people without diabetes. In those with diabetes, cardiovascular complications occur at an earlier age and often result in premature death, making heart disease the major killer of diabetic people. But why is heart disease so prevalent among diabetics? view more (2007-08-13)
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