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Is the spleen able to prohibit tumor cell proliferation?
Primary and metastatic tumors of the spleen are described as unusual, excluding involvement by lymphoma. Indeed, isolated splenic metastasis from colorectal carcinoma is not a common occurrence. Its rareness has been hypothetically explained by several characteristics of the spleen, such as... view more (2007-10-17)

18F-DG PET/CT can highly increase the detection of colorectal cancer
Combined positron emission tomography and computed tomography (PET/CT) is currently widely used in the clinical diagnosis of cancer to provide functional and morphological imaging.   view more (2007-10-11)

Which is accurate, CT or MRI?
Paraaortic lymph node metastasis in patients with pancreatico-biliary carcinoma has been reported as a definite predictor of early recurrence and shorter survival term.   view more (2008-05-21)

Early results indicate radiofreqency ablation useful in treating ovarian cancer metastasis
Percutaneous radiofrequency ablation, a procedure that uses a high frequency electric current to kill tumor cells, is effective in achieving local control in selected patients with metastasis from ovarian cancer.   view more (2006-09-29)

A new significance of LVD and angiogenic MVD is identified in human primary SCRC
Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis. Angiogenesis has established its role in the development and progression of a variety of malignancies, playing a crucial role in the dissemination of the tumor cells.   view more (2008-01-17)

Researchers identify mechanism used by gene to promote metastasis in human cancer cells
Virginia Commonwealth University Institute of Molecular Medicine and VCU Massey Cancer Center researchers have discovered how a gene, melanoma differentiation associated gene-9/syntenin (mda-9/syntenin), interacts with an important signaling protein to promote metastasis in human melanoma cells, a... view more (2008-09-30)

Scientists from the University of Navarra find 5 genes involved in the metastasis of breast tumours to the lung
The identification of five genes involve in the metastasis of breast tumours to the lung is the principal finding of a scientific team made up of two bodies from the University of Navarra, the Applied Medical Research Centre (CIMA) and the University Hospital of the University of Navarra.   view more (2008-06-23)

Molecules can block breast cancer's ability to spread
Researchers have identified a specific group of microRNA molecules that are responsible for controlling genes that cause breast cancer metastasis.   view more (2008-01-10)

Molecular markers signal early metastases from ocular melanoma
Patients with melanoma of the eye are at risk for liver metastases, which are often not detected until they have turned into large, lethal tumors.   view more (2006-09-14)

Markers that can predict cancer spread could save women from unnecessary chemotherapy
Women with early breast cancer could avoid needless chemotherapy thanks to work carried out in Chicago on identifying biochemical markers which indicate whether or not cancer is likely to spread to other parts of the body, the 3rd European Breast Cancer Conference in Barcelona heard today (Saturday... view more (2002-03-21)

Post-pregnancy events promote breast tumor metastasis
Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells.   view more (2006-02-03)

Ethanol injection helps manage bone metastasis in thyroid cancer patients
Percutaneous ethanol injection (PEI)-an injection of ethanol (alcohol) through the skin directly into a bone tumor to kill cancer cells-may be a valuable ancillary treatment for thyroid cancer patients whose cancer has spread to the bone. Japanese researchers announced these findings during the... view more (2007-06-04)

Genes set scene for metastasis
Biologists at Memorial Sloan-Kettering Cancer Center (MSKCC) have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor.   view more (2007-04-12)

New technique detects early metastasis of breast cancer
In the U.S., a novel technology soon may be available to detect the spread, or metastasis, of breast cancer earlier than now possible, according to research presented at the first international meeting on Molecular Diagnostics in Cancer Therapeutic Development.   view more (2006-09-14)

How does Fu-Zheng-Jie-Du-Decoction act on PTEN expression in hepatocellular carcinoma?
Many hepatocellular carcinoma (HCC) patients in China may be treated with Traditional Chinese medicine (TCM). Some say it works, others doubt its effectiveness. These stated that a research group in China had found TCM can down-regulate the expression of PTEN in HCC, which may suppress tumor cell... view more (2008-01-17)

Jefferson scientists identify protein key to breast cancer spread, potential new drug target
Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread.   view more (2007-04-10)

UC San Diego researchers improve accuracy of breast cancer prognoses
One of the many unknowns facing women who are diagnosed with breast cancer is predicting the likelihood that the cancer will spread to other parts of the body - metastasize.   view more (2007-10-16)

Stabilizing cancer-fighting p53 can also shield a metastasis-promoter
Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, according to research by scientists at The University of Texas M. D. Anderson Cancer Center reported in the current issue of the... view more (2008-05-23)

Curcumin halts spread of breast cancer in mice
Curcumin, the main ingredient of turmeric and the compound that gives curry its mustard-yellow color, inhibits metastasis to the lungs of mice with breast cancer.   view more (2005-10-17)

Inflammation may play role in metastasis of prostate cancer
Many would assume that "mounting an immune response" or "having your body fight the cancer" is a good thing. Now, research at the University of California, San Diego (UCSD) School of Medicine strongly suggests that inflammation associated with the progression of tumors actually... view more (2007-03-19)

UNC researchers find clue to stopping breast-cancer metastasis
If scientists knew exactly what a breast cancer cell needs to spread, then they could stop the most deadly part of the disease: metastasis. New research from the University of North Carolina at Chapel Hill School of Medicine takes a step in that direction.   view more (2008-11-18)

Jefferson, Ohio State team find gene signature profile for metastasis
A common signature of tiny, specific pieces of non-coding genetic material known as microRNAs (miRNAs) may be directly involved in the spread of cancer to other parts of the body.   view more (2008-06-02)

Researchers identify gene set linked to breast cancer's spread to lungs
In a potential advance for the treatment of aggressive breast cancer, scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) have identified a set of genes in breast tumors that appear to predict if the disease will spread to the lungs and, once there, how virulent it will become.   view more (2005-07-28)

Loss of caspase-8 makes neuroblastoma more aggressive
The caspase-8 gene plays a critical role in suppressing metastasis (spread) of neuroblastoma, and the expression of this gene is frequently absent in cancer cells that are aggressively metastasizing.   view more (2006-01-06)

The effective chemoradiotherapy method for pancreatic cancer
Pancreatic cancer is the fifth most common cause of cancer death in Japan. The prognosis is extremely poor because it is difficult to detect this disease in the early stage and also the postoperative incidence of recurrence is still high, and we have not had any effective treatment for inoperable... view more (2008-09-22)
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