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HER2 levels may aid in treatment selection for metastatic breast cancer
Findings published in the December 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, show lapatinib benefits women with HER2-positive breast cancer, while women with HER2-negative breast cancer or those who express EGRF alone derive no incremental benefit.   view more (2008-12-03)

A new pharmaceutical drug that halts progress of metastatic kidney cancer
Research has shown the efficacy of a pharmaceutical drug known as sunitinib which halts progress of metastatic kidney cancer.   view more (2007-03-02)

New prostate cancer marker helps identify men whose cancer is likely to spread
Prostate cancer researchers at Sydney's Garvan Institute, supported by the Cancer Institute NSW, have found a new marker for identifying aggressive prostate cancers.   view more (2006-10-04)

Scientists are developing markers capable of spotting minute numbers of cancer cells in blood
Scientists have identified three molecular markers which, when used together, are capable of detecting minute amounts of metastatic cancer cells in the blood of patients. Although this research is in its early days, they hope it will lead to the development of a simple and easy test to spot cancer cells that are spreading from the original tumour.... view more... (2002-03-21)

MicroRNA-mediated metastasis suppression
Metastases are responsible for over 90% of cancer deaths. In the upcoming issue of G&D, Dr. Robert Weinberg (MIT) and colleagues lend molecular insight into how microRNAs suppress tumor metastasis.    view more (2009-10-29)

Stem cells as cancer therapy
It is widely hoped that neural stem cells will eventually be useful for replacing nerves damaged by degenerative diseases like Alzheimer disease and multiple sclerosis. But there may also be another use for such stem cells-delivering anti-cancer drugs to cancer cells.   view more (2006-12-26)

Newly diagnosed breast cancer patients benefit from use of USFNA of lymph nodes
Ultrasound-guided fine needle aspiration (USFNA) of the lymph nodes is a safe, useful, and minimally invasive procedure for diagnosing metastatic disease in patients who are undergoing preoperative staging for breast cancer, according to a recent study conducted by researchers at the Rhode Island Hospital/Warren Alpert Medical School of Brown... view more... (2008-04-14)

New therapy recommendations for spinal complications of cancer
Cancer patients and their physicians have new answers as they seek the best treatment for the immobilizing trauma of spinal cord compression in metastatic cancer, thanks to Roy Patchell and colleagues at the University of Kentucky.   view more (2005-08-22)

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma
Hoag Memorial Hospital Presbyterian today announced promising data from a clinical study showing patient-specific cancer vaccines derived from patients' own cancer cells and immune cells were well tolerated and resulted in impressive long-term survival rates in patients with metastatic melanoma whose disease had been minimized by other therapies.   view more (2009-07-29)

A safe, well-tolerated, and effective treatment for metastatic esophageal cancer
Metastatic esophageal squamous cell cancer has very poor prognosis. Conventional surgery is considered the most effective treatment, but many cases are inoperable at the time of diagnosis.   view more (2009-02-23)

A new theoretical model of tumor growth and metastasis based on differences in tissue pressure
The HFSP Journal, the interdisciplinary journal for scientists conducting high quality, innovative research at the interface between biology and the physical sciences is pleased to announce that the latest article modelling of tumor growth and metastasis.   view more (2009-03-24)

Einstein researchers identify potential target for metastatic cancer
The deadliest part of the cancer process, metastasis, appears to rely on help from macrophages, potent immune system cells that usually defend vigorously against disease, researchers at Albert Einstein College of Medicine of Yeshiva University report.   view more (2009-08-11)

Less-toxic drug prolongs survival in metastatic breast cancer
Research from the Northwestern University Feinberg School of Medicine has found that a less toxic, solvent-free chemotherapy drug more effectively prevents the progression of metastatic breast cancer and has fewer side effects than a commonly used solvent-based drug.   view more (2009-05-27)

Preliminary study shows promise for treatment of renal cell cancer
A new study suggests that sunitinib is a promising agent for treatment of metastatic renal cell cancer, currently a disease without highly effective treatment options.   view more (2006-06-07)

Survival predictors may help customize treatment options for men with metastatic prostate cancer
Four risk factors that help predict how long men may survive with metastatic prostate cancer could help doctors choose more effective treatments, according to a study led by researchers in the Duke Comprehensive Cancer Center.   view more (2009-05-15)

Mayo Clinic reports new option for patients with metastatic melanoma
Patients with metastatic melanoma (MM) have new hope, says a recently published study by Mayo Clinic Cancer Center.   view more (2006-01-04)

Boston College biologists build a better mouse model for cancer research
Researchers at Boston College have developed the first laboratory mouse model that mimics cancer's spread through the human body. Using their novel cell line, the team discovered one of the body's primary defensive cells plays a role in cancer's attack.   view more (2008-04-10)

Lung cancer cells activate inflammation to induce metastasis
A research team from the University of California, San Diego School of Medicine has identified a protein produced by cancerous lung epithelial cells that enhances metastasis by stimulating the activity of inflammatory cells.   view more (2009-01-05)

Model identifies genes that induce normal skin cells to become abnormal
Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.   view more (2005-11-15)

Colorectal cancer
Previously, only a few genes had been associated with the formation of metastases in colorectal cancer. Now, researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité - University Medicine Berlin, Germany, have identified 115 genes that are disregulated both in the primary tumor and in its metastases.   view more (2009-07-01)
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