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DNA editing tool flips its target
Imagine having to copy an entire book by hand without missing a comma. Our cells face a similar task every time they divide. They must duplicate both their DNA and a subtle pattern of punctuation-like modifications on the DNA known as methylation.   view more (2008-09-04)

Making memories that last a lifetime
Neurobiologists have discovered a mechanism by which the constantly changing brain retains memories—from that dog bite to that first kiss. They have found that the brain co-opts the same machinery by which cells stably alter their genes to specialize during embryonic development.   view more (2007-03-15)

DFG Presents The 2004 MAK And BAT Value Lists
The Senate Commission of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) on the Investigation of Health Hazards of Chemical Compounds in the Work Area has presented the 2004 Maximum Allowable Concentration (Maximale Arbeitsplatzkonzentrationen - MAK) and Biological Tolerance... view more (2004-07-29)

'Swish-and-spit' test accurate for cancer
A morning gargle could someday be more than a breath freshener - it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk,... view more (2008-01-02)

Sniffing out chloride
When industrial plants are wrecked, they often leave behind a site with contaminated soil. If it was a metalworking plant, a textile production or dry-cleaning facility, a paint manufacturing or an animal waste processing plant, the soil is often contaminated with chlorine-based solvents. In order... view more (2002-09-09)

Novel regulatory mechanism identified for key tumor suppressor p53
Collaborating scientists from The Wistar Institute in Philadelphia and The Vienna Biocenter in Austria have identified a novel mechanism involved in normal repression of the p53 protein, perhaps the single most important molecule for the control of cancer in humans.   view more (2006-11-16)

Gold nanoparticles help detect a toxic metal -- mercury
With gold nanoparticles, DNA and some smart chemistry as their tools, scientists at Northwestern University have developed a simple "litmus test" for mercury that eventually could be used for on-the-spot environmental monitoring of bodies of water, such as rivers, streams, lakes and... view more (2007-04-27)

In a technical tour de force, Salk scientists take a global view of the epigenome
A collaboration between researchers at the Salk Institute for Biological Studies and the University of California at Los Angeles captured the genome-wide DNA methylation pattern of the plant Arabidopsis thaliana-the "laboratory rat" of the plant world-in one big sweep.   view more (2006-09-01)

Embargo Of Release Lifted: Execution By Lethal Injection Is Not Humane Or Painless Suggests Study
Prisoners executed by lethal injection in the US may have experienced awareness and unnecessary suffering because they were not properly sedated, concludes a research letter in this week's issue of THE LANCET. The authors believe the use of lethal injection should cease in order to prevent... view more (2005-04-13)

Shilatifard and colleagues identify a potential target for treatment of mixed lineage leukemia
Ali Shilatifard, Ph.D., Investigator, has identified a cellular factor that can reverse histone trimethylation caused by the trithorax gene, the Drosophila homologue of the human mixed lineage leukemia gene, MLL. MLL, which is found in translocations in a variety of hematological malignancies, is a... view more (2007-03-12)

Anti-perfume - the male butterfly's gift to his partner
Pieris butterflies are not like all other butterflies. Both sexes agree about sex. In a dissertation about olfactory communication, Johan Andersson, a scientist at the Royal Institute of Technology in Stockholm (KTH), Sweden, presents exciting new findings about a joint effort that provides an... view more (2004-02-23)

Cells in mucus from lungs of high-risk patients can predict tumor development
n a group of high-risk patients, a test that examined DNA from cells expelled in sputum for evidence of "silenced" genes correctly identified the majority of patients who were later diagnosed with lung cancer.   view more (2006-03-15)

Little Evidence Behind Bronchodilator Therapy for Cystic Fibrosis
Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis, according to a new systematic review of published research.   view more (2005-10-26)

Sea salt worsens coastal air pollution: study
Air pollution in the world's busiest ports and shipping regions may be markedly worse than previously suspected, according to a new study showing that industrial and shipping pollution is exacerbated when it combines with sunshine and salty sea air.   view more (2008-04-09)

The risk factors of abdominal venous thrombosis
Abdominal venous thrombosis may present as BCS or SVT. Hereditary and acquired risk factors have been implicated in the etiopathogenesis of abdominal venous thrombosis   view more (2008-10-13)

Stomach ulcer bug causes bad breath
Bacteria that cause stomach ulcers and cancer could also be giving us bad breath, according to research published in the December issue of the Journal of Medical Microbiology.   view more (2008-11-24)

Prenatal Exposure To Mercury In Fish Not Associated With Impaired Neurodevelopment (p 1667, 1686)
Authors of a longitudinal study investigating a possible link between prenatal mercury exposure from ocean fish and impaired neurodevelopment in children report their latest findings in this week's issue of THE LANCET. The results confirm earlier findings that prenatal exposure to mercury in the... view more (2003-05-14)

Cyanobacteria ("blue-green algae") produce toxin with possible connection to neurodegerative disorders
It is well known that a tiny number of cyanobacteria, previously known as blue-green algae, produce substances that can be toxic to both humans and animals. Now a research team from Sweden, Scotland, and the U.S. has found that a further toxin (BMAA, -methyl amino-alanine) with a possible... view more (2005-04-08)

Unusual carbohydrate structure in the cell walls of tuberculosis bacteria-a new point of attack for drugs?
Even though we have lost much of our fear of tuberculosis in the industrialized countries, according to the WHO about 2 mio. people worldwide die each year of this infectious disease. Researchers at the University of Leeds have now discovered a carbohydrate with an unusual structure in the cell... view more (2004-07-27)

Protein holds back growth of head and neck tumors
A protein associated with the growth of head and neck tumors may be a tumor suppressor that could prevent the spread of cancer when it is expressed above normal levels.   view more (2006-02-01)

Water theory is watertight, researchers say
There may be tiny bubbles in the wine, but not at the interface between water and a waxy coating on glass, a new study shows.   view more (2007-01-18)

Stem cells could reveal secrets of illness in later life
Mums to be have known for some time that what they eat when pregnant affects their unborn child but now scientists believe that the diet of our mothers during pregnancy may even affect our predisposition to illnesses such as heart disease, diabetes and high blood pressure in late life.   view more (2004-12-24)

Evolutionary shifts in olfactory sensitivities in fruit flies
How do an animal's senses change as it evolves to occupy a new ecological niche? By comparing the olfactory system of the fruit fly Drosophila melanogaster, which feeds from multiple fruit types, with that of its sibling species D. sechellia, a specialist particularly drawn to a single fruit type.   view more (2006-01-10)

Researchers explore the antidepressant effects of ketamine
Drug treatments for depression can take many weeks for the beneficial effects to emerge. The excruciating and disabling nature of depression highlights the urgency of developing treatments that act more rapidly.   view more (2008-02-22)

Scientists unravel the genetic coding of the pea
The pea is one of many important crop species that is unsuited to the Agrobacterium-based genetic modification techniques that are commonly used to work with crops.   view more (2008-02-26)
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