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Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute.   view more (2008-05-09)

Change in gene may be underlying molecular defect in some colorectal cancers, study suggests
Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer.   view more (2005-09-21)

Study links breast cancer risk to epigenetic changes related to race, smoking and birth size
Women can encounter environmental factors that increase their risk of breast cancer at various periods of their physical development, beginning before birth and extending until menopause.   view more (2007-04-16)

Cough medicine fights dyskinesias in Parkinson's
A cough suppressant and a drug tested as a schizophrenia therapy curb the involuntary movements that are disabling side effects of taking the Parkinson's disease medication levodopa, Portland scientists have found.   view more (2007-11-08)

Prenatal Genistein In Soy Reduces Obesity In Offspring
A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center.   view more (2006-03-29)

Gene-regulating enzyme is also a target for anti-depressive drugs
In 2005, professor Ramin Shiekhattar, Ph.D., at The Wistar Institute and his colleagues reported details about an enzyme involved in appropriately repressing sets of neuronal genes in non-neuronal cells.   view more (2006-06-26)

Blue-Green Algal Links to Alzheimer's-Like Neurological Disease
An international team of researchers, including scientists from the University of Dundee have announced that cyanobacteria (blue-green algae) found throughout the world may produce a toxin linked to certain types of neurological disease.   view more (2005-04-05)

New insight about the source of anxiety in Rett syndrome
A peptide known to play a role in anxiety is overly plentiful in a mouse model of the inherited neurological disorder Rett syndrome and appears to underlie the anxiety-like behavior in these mice.   view more (2006-11-14)

How Rett Syndrome mutation targets the brain
Researchers have pinpointed why mutations that cause Rett Syndrome (RTT)-among the leading causes of mental retardation in females-specifically target the brain rather than other body tissues.   view more (2006-10-19)

The pain from fibromyalgia is real, researchers say
Many people with fibromyalgia - a debilitating pain syndrome that affects 2 to 4 percent of the population - have faced the question of whether the condition is real.   view more (2006-11-29)

Depression model leaves mice with molecular scar
In addition to triggering a depression-like social withdrawal syndrome, repeated defeat by dominant animals leaves a mouse with an enduring "molecular scar" in its brain that could help to explain why depression is so difficult to cure.   view more (2006-03-01)

Technological advances could reduce effectiveness of the Chemical Weapons Convention
Technological advances within the chemical industry could erode the effectiveness of the Chemical Weapons Convention's provisions for verification and compliance.   view more (2005-08-15)

Opening and closing the genome
At any given time, most of the roughly 30,000 genes that constitute the human genome are inactive, or repressed, closed to the cellular machinery that transcribes genes into the proteins of the body.   view more (2007-02-26)

Computer-designed molecule to clean up fluorocarbons?
The chemical bond between carbon and fluorine is one of the strongest in nature, and has been both a blessing and a curse in the complex history of fluorocarbons. Now, in a powerful demonstration of the relatively new field of "computational chemistry".   view more (2007-03-05)

Power plants are major influence in regional mercury emissions
The amount of mercury emitted into the atmosphere in the Northeast fluctuates annually depending on activity in the electric power industry, according to researchers at the Yale School of Forestry & Environmental Studies.   view more (2006-07-24)

Marine Algae A Weapon Against Global Warming?
"Parforce" an EU-funded research project has discovered a new link between marine algae and climate change. Researchers working on the project found out that iodine vapours, released from algae or plankton, condense over oceans to form aerosols . These aerosols, which tend to counter "global... view more (2002-07-18)

Scientists find clue to mechanisms of gene signaling and regulation
Scientists have discovered a pattern in the DNA sequence of the mouse genome that may play a fundamental part in the way DNA molecules regulate gene expression.   view more (2007-08-23)

Ultrafast laser spectrometer measures heat flow through molecules
Global warming isn't the only heat scientists are feeling. Another area in which heat flow is becoming crucial is the field of molecular electronics, where long-chain molecules attached to tiny electrodes are used to transport and switch electrons.   view more (2007-08-10)

Human embryonic stem cells display a unique pattern of chemical modification to DNA
Scientists from the Burnham Institute for Medical Research (BIMR) and Illumina Inc., in collaboration with stem cell researchers around the world, have found that the DNA of human embryonic stem cells is chemically modified in a characteristic, predictable pattern.   view more (2006-08-07)

Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
New evidence indicates that the loss of two types of brain cells--not just one as previously thought--may trigger the onset of symptoms associated with Parkinson's disease.   view more (2007-08-14)

Glowing Results-Pitt Researchers Use Fluorescence to Develop Fast, Simple Method for Detecting Mercury in Fish and Dental Fillings
Researchers at the University of Pittsburgh have developed a simple and quick method for detecting mercury in fish and dental samples, two substances at the center of public concern about mercury contamination.   view more (2008-11-19)

MTBE contamination: A microbial approach for groundwater
Max Häggblom's Rutgers laboratory has taken an important step on the path to using microbes to rid the environment of methyl tertiary-butyl ether (MTBE), a toxic gasoline additive now classified as a potential human carcinogen.   view more (2006-03-22)

New molecules discovered that block cancer cells from modifying cell DNA
Researchers have discovered new small molecules that may prevent prostate cancer cells from turning off normal genes in a process that transforms normal cells into cancer cells.   view more (2007-10-12)

U of I scientist develops enzyme inhibitor that may slow cancer growth
University of Illinois scientist Tim Garrow, in collaboration with Jiri Jiracek of the Czech Academy of Sciences, has applied for a provisional patent on a class of chemicals that has future therapeutic uses in medicine, specifically cancer treatment.   view more (2006-07-07)

Organic & Biomolecular Chemistry
First Advance Articles Now Available Free Online The first issue of Organic & Biomolecular Chemistry, formed from the merger and strategic development of Perkin Transactions 1 & 2, will be published on 10 January 2003. The electronic version will go up on 23 December 2002. Barbara... view more (2002-12-05)
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