Methylation Current Events | Methylation News | 3
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Study finds genomic changes in the brains of people who commit suicide
Are genes destiny? Alternatively, are we simply the products of our environment? There is a growing sense that neither of these two possibilities fully captures the essence of the risk for psychiatric disorders. view more (2008-10-23)
Novel enzyme offers new look at male hormone regulation
For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent. view more (2006-05-08)
Centromeres cross over, a lot
Recombination at centromeres is higher than anywhere else on the chromosome, even though methyltransferases do their best to prevent it, say Jaco et al., as published in the June 16 issue of the Journal of Cell Biology. view more (2008-06-13)
'Smothered' genes combine with mutations to yield poor outcome in cancer patients
Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients. view more (2008-07-16)
Cancer's distinctive pattern of gene expression could aid early screening and prevention
Distinctive patterns of genes turned off - or left on - in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say. view more (2009-07-28)
First evidence that prenatal exposure to famine may lead to persistent epigenetic changes
A study initiated by researchers at Columbia University Mailman School of Public Health and the Leiden University Medical Center in the Netherlands suggests that prenatal exposure to famine can lead to epigenetic changes that may affect a person's health into midlife. view more (2008-10-31)
Novel regulatory mechanism identified for key tumor suppressor p53
Collaborating scientists from The Wistar Institute in Philadelphia and The Vienna Biocenter in Austria have identified a novel mechanism involved in normal repression of the p53 protein, perhaps the single most important molecule for the control of cancer in humans. view more (2006-11-16)
New Method Developed by UC San Diego Bioengineers Gives Regenerative Medicine a Boost
Bioengineers at UC San Diego have developed a breakthrough method for sequencing-based methylation profiling, which could help fuel personalized regenerative medicine and even lead to more efficient and cost-effective methods for studying certain diseases. view more (2009-04-24)
Profiling of cancer genes may lead to better and earlier detection
A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers - lung, breast, prostate and colon cancer. view more (2006-12-27)
How plants remember winter, in order to flower in spring
Scientists at the John Innes Centre (JIC) Norwich (1), have discovered the molecular change that allows plants to remember winter. Many plants need a cold period (3-8 weeks at 4o - 8oC) early in their growth to stimulate them to flower, this is called vernalisation, and without a suitable cold treatment flowering is delayed. JIC scientists have... view more... (2004-01-06)
Colon cancer shuts down receptor that could shut it down
Though a high-fiber diet has long been considered good for you and beneficial in staving off colon cancer, Medical College of Georgia researchers have discovered a reason why: roughage activates a receptor with cancer-killing potential. view more (2009-04-14)
Researchers find protein that silences genes
A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off - in this case, the turning off of thousands of nearly identical genes in a hybrid plant. view more (2006-05-08)
Silence please
Researchers at Cambridge University have been studying the process of gene silencing in transgenic plants, and have cloned a genetic modifier that could reduce transgene instability. Dr Ian Furner will be presenting the results of the study at the Society for Experimental Biology conference on Monday 8 April. view more (2002-04-04)
Researchers discover RNA repair system in bacteria
In new papers appearing this month in Science and the Proceedings of the National Academy of Sciences, University of Illinois biochemistry professor Raven H. Huang and his colleagues describe the first RNA repair system to be discovered in bacteria. view more (2009-10-13)
Prenatal Genistein In Soy Reduces Obesity In Offspring
A single nutrient found in soy products elicits changes in gene behavior that permanently reduce an embryo's risk of becoming obese later in life, according to an animal study at Duke University Medical Center. view more (2006-03-29)
New molecules discovered that block cancer cells from modifying cell DNA
Researchers have discovered new small molecules that may prevent prostate cancer cells from turning off normal genes in a process that transforms normal cells into cancer cells. view more (2007-10-12)
Finding may eventually help tailor treatment for depression
When a treatment works for one person's depression, it does not always work for another person's. Findings from the University of Iowa may one day help doctors have a better idea of who will benefit from specific antidepressants, increasing the likelihood of successful treatment. view more (2007-11-08)
New DNA Test Uses Nanotechnology to Find Early Signs of Cancer
Using tiny crystals called quantum dots, Johns Hopkins researchers have developed a highly sensitive test to look for DNA attachments that often are early warning signs of cancer. view more (2009-08-18)
Stem cells could reveal secrets of illness in later life
Mums to be have known for some time that what they eat when pregnant affects their unborn child but now scientists believe that the diet of our mothers during pregnancy may even affect our predisposition to illnesses such as heart disease, diabetes and high blood pressure in late life. view more (2004-12-24)
Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
A study published in this week's online issue of Nature Biotechnology, demonstrates a unique and highly sensitive method for detecting methylation-associated cancers. view more (2009-08-17)
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