Methylation Current Events | Methylation News | 4
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New nucleotide could revolutionize epigenetics
Anyone who studied a little genetics in high school has heard of adenine, thymine, guanine and cytosine -- the A,T,G and C that make up the DNA code. view more (2009-04-17)
Researchers may have unlocked the mechanisms that silence the estrogen receptor gene alpha during breast cancer
The mechanisms that silence the estrogen receptor gene alpha (ER-α) in certain breast cancer cell lines may be closer to being unlocked. view more (2007-08-20)
Breast cancer amongst young women
Breast cancer is the most common and the second-most fatal malignant tumour amongst women who live in industrialised countries. Moreover, when present in young women, it would appear that a genetic predisposition is involved. This predisposition can be due to a number of causes and, amongst the most common, lie the alterations in the gene... view more... (2003-11-14)
Researchers find better prostate cancer indicators
Researchers at Mayo Clinic have narrowed the search for effective prostate cancer biomarkers (genetic variations that point to a specific disease or condition), identifying changes in the expression of genes of the whole genome closely correlated to prostate cancer development and progression. view more (2006-03-28)
Study links breast cancer risk to epigenetic changes related to race, smoking and birth size
Women can encounter environmental factors that increase their risk of breast cancer at various periods of their physical development, beginning before birth and extending until menopause. view more (2007-04-16)
Enzyme complex thought to promote cancer development can also help prevent it
In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development. view more (2005-10-14)
Trial shows which brain cancer patients benefit from temozolomide
Genetic predictive test clears way for targeted drug treatment view more (2004-09-26)
USC study in Nature Genetics supports a stem cell origin of cancer
Researchers at the University of Southern California (USC) recently made significant strides toward settling a decades-old debate centering on the role played by stem cells in cancer development. view more (2007-01-10)
New blood tests promise simple, cost-effective diagnosis of gastrointestinal cancers
Promising results from two new blood tests that can aid in the early identification of patients with gastrointestinal (GI) cancers will be presented at Europe's largest cancer congress. view more (2009-09-21)
Stem cells give clues to understanding cancer and make breakthrough in childhood leukaemia
Scientists in Switzerland are uncovering new clues about how cancer cells grow - and how they can be killed - by studying stem cells, 'blank' cells that have the potential to develop into fully mature or 'differentiated' cells and other scientists in UK have made a breakthrough in understanding the cause of the most common form of childhood... view more... (2008-02-14)
Embryonic stem cells accrue genetic changes
An international team of researchers has discovered that human embryonic stem cell lines accumulate changes in their genetic material over time. view more (2005-09-06)
NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis. view more (2008-03-27)
A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline. view more (2007-06-07)
Why don't brain tumors respond to medication?
Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance. view more (2009-09-01)
Regulating the Nuclear Architecture of the Cell
An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell's most critical functions: it manufactures ribosomes, the molecular machines that convert the genetic information carried by messenger RNA into proteins that do the work of life. view more (2006-12-11)
Child abuse may 'mark' genes in the brains of suicide victims
A team of McGill University scientists has discovered important differences between the brains of suicide victims and so-called normal brains. Although the genetic sequence was identical in the suicide and non-suicide brains, there were differences in their epigenetic marking - a chemical coating influenced by environmental factors. view more (2008-05-07)
'Swish-and-spit' test accurate for cancer
A morning gargle could someday be more than a breath freshener - it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers. view more (2008-01-02)
Shilatifard and colleagues clarify the enzymatic activity of factors involved in childhood leukemia
The Stowers Institute's Shilatifard Lab and colleagues have provided new insight into the molecular basis for H3K4 methylation, an activity associated with the MLL protein found in chromosomal translocation-based aggressive infant acute leukemias. view more (2009-05-05)
Cells in mucus from lungs of high-risk patients can predict tumor development
n a group of high-risk patients, a test that examined DNA from cells expelled in sputum for evidence of "silenced" genes correctly identified the majority of patients who were later diagnosed with lung cancer. view more (2006-03-15)
Testes stem cell can change into other body tissues, Stanford/UCSF study shows
Scientists at the Stanford University School of Medicine and at UC-San Francisco have succeeded in isolating stem cells from human testes. view more (2009-01-06)
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