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MicroRNAs make for safer cancer treatments
Viruses -- long regarded solely as disease agents -- now are being used in therapies for cancer. Concerns over the safety of these so-called oncolytic viruses stem from their potential to damage healthy tissues.   view more (2008-10-27)

Biologists develop genome-wide map of miRNA-mRNA interactions
Researchers at New York University's Center for Comparative Functional Genomics and the University of California, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans).   view more (2006-03-09)

Genetic predictors of esophageal cancer identified
Researchers have identified 11 genotypes that may increase esophageal cancer risk, according to research published in the November issue of Cancer Prevention Research, a journal of the American Association for Cancer Research.   view more (2008-11-05)

Yale scientists show that a microRNA can reduce lung cancer growth
A small RNA molecule, known as let-7 microRNA (miRNA), substantially reduced cancer growth in multiple mouse models of lung cancer, according to work by researchers at Yale University and Asuragen, Inc., published in the journal Cell Cycle.   view more (2008-03-24)

How body size is regulated: International study discovers ten new genes related to human growth
Scientists are beginning to unravel the question why people distinctly vary in size.   view more (2008-05-12)

Jefferson pharmacologist says biomarker discovery bodes well for better cancer diagnostics
While new findings from Ohio State University scientists suggest a genetic marker that could help distinguish between chronic pancreatitis and pancreatic cancer and gauge who will do well with cancer treatment, a pharmacologist at the Kimmel Cancer Center at Jefferson in Philadelphia sees the... view more (2007-05-02)

Scientists complete DNA sequencing and analysis of multiple fruit fly genomes
In one of the first large-scale comparisons of multiple animal genomes, scientists at the Broad Institute of MIT and Harvard, the Computer Science and Artificial Intelligence Laboratory (CSAIL) at MIT, and many collaborating institutions, have analyzed the genomes of twelve species of the fruit fly... view more (2007-11-08)

New biomarkers for lupus found
A Wake Forest University School of Medicine team believes it has found biomarkers for lupus that also may play a role in causing the disease.   view more (2006-11-13)

MicroRNAs may be key to HIV's ability to hide, evade drugs, Jefferson scientists find
Tiny pieces of genetic material called microRNA (miRNA), better known for its roles in cancer, could be a key to unlocking the secrets of how HIV, the AIDS virus, evades detection, hiding in the immune system.   view more (2007-10-01)

Tiny molecule controls stress-induced heart disease
A tiny snippet of RNA, a chemical cousin of DNA, controls damage to the heart under several types of stress, researchers at UT Southwestern Medical Center have found.   view more (2007-03-23)

Massive microRNA scan uncovers leads to treating muscle degeneration
Researchers have discovered the first microRNAs - tiny bits of code that regulate gene activity - linked to each of 10 major degenerative muscular disorders, opening doors to new treatments and a better biological understanding of these debilitating, poorly understood, often untreatable diseases.   view more (2007-10-18)

New Class of RNA Molecules May Be Important in Human Cancer
Research here shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer.   view more (2007-09-12)

Research suggests targeted treatment strategies for lupus
New research provides clues about the causes of lupus symptoms and suggests specific new targeted treatment strategies, according to Nilamadham Mishra, M.D., from Wake Forest University Baptist Medical Center, in presentations this week at the American College of Rheumatology in Boston.   view more (2007-11-12)

CSHL scientists identify and repress breast cancer stem cells in mouse tissue
By manipulating highly specific gene-regulating molecules called microRNAs, scientists at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue - cells that are widely thought to give rise to cancer.   view more (2007-12-18)

MiRNA Fingerprint Identified in Platelet Formation
Scientists have identified a handful of microRNAs (miRNAs) that appear to play a significant role in the development of platelets - blood cells critical to the body's ability to form clots following an injury.   view more (2006-03-17)

Not all embryonic stem cell lines are created equal
When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each... view more (2007-08-07)

Role of microRNA Identified in Thyroid Cancer
The presence of only five tiny strands of RNA is enough to clearly distinguish cancerous thyroid tissue from otherwise normal tissue, scientists say.   view more (2005-12-23)
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