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MicroRNAs help control HIV life cycle
Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. view more (2009-06-26)
Throwing the micro switch: MicroRNA may link smoking risk gene to neurobiology of addiction
During the past several years, significant progress has been made in identifying susceptibility genes for nicotine dependence through genetic linkage and association analyses. view more (2009-04-23)
Cancer researchers link DICER1 gene mutation to rare childhood cancer
Research published today in Science Express from the journal Science demonstrates the first definitive link between mutations in the gene DICER1 and cancer. view more (2009-06-26)
Researchers identify genetic markers for aggressive head and neck cancer
Scientists at Albert Einstein College of Medicine of Yeshiva University have identified genetic markers that signal poor outcomes for patients with head and neck cancer. These findings could one day lead to a genetic test that could help select or predict successful treatment options for patients with this type of cancer. The results were... view more... (2009-03-19)
miR-196a promotes the metastases of tumors
MicroRNAs are small RNA molecules of 20-25 nucleotides length, regulating gene expression by inhibition of transcription or translation of proteins. view more (2009-05-13)
Protein protects embryonic stem cells' versatility and self-renewal
A protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature. view more (2008-03-24)
Short RNA strand helps exposed skin cells protect body from bacteria, dehydration and even cancer
Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier. view more (2008-03-03)
MicroRNA may have fail-safe role in limb development
A tiny strand of molecules plays a role in how our arms and legs develop and grow-a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University. view more (2005-12-02)
Not all embryonic stem cell lines are created equal
When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. view more (2007-08-07)
Minuscule molecules pack a powerful punch
A role for a microRNA in the immune system has been shown by study of one of the world's first microRNA knockout mouse, reported Friday 27 April in Science. view more (2007-04-27)
Research uncovers clues to virus-cancer link
In a series of recently-published articles, a research team from the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients. view more (2009-06-18)
Advances in lung cancer research announced at conference
Dr. Glen Weiss of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare this week announced two significant advances in treating lung cancer at an international cancer research conference. view more (2009-08-10)
Oregon researchers discover a mechanism leading to cleft palate
By creating a genetic mutation in zebrafish, University of Oregon scientists say they've discovered a previously unknown mechanism for cleft palate, a common birth defect in humans that has challenged medical professionals for centuries. view more (2008-02-12)
Gladstone scientists identify genetic factors that hold promise for treatment of vascular diseases
Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) have discovered a key switch that makes stem cells turn into the type of muscle cells that reside in the wall of blood vessels. view more (2009-07-06)
Genomatix integrates genome-wide open chromatin from next generation sequencing
Genomatix Software GmbH, a Systems Biology company focussed on high quality annotation and the understanding of gene regulation, has begun showcasing its abilities in the analysis of data generated by Next Generation Sequencing (NGS) technology. view more (2008-02-26)
Gene variations alter risk of esophageal cancer
Variations in a common gene pathway may affect esophageal cancer risk, a dangerous and rapidly increasing type of cancer, according to research by scientists at The University of Texas M. D. Anderson Cancer Center. view more (2008-11-06)
Research suggests targeted treatment strategies for lupus
New research provides clues about the causes of lupus symptoms and suggests specific new targeted treatment strategies, according to Nilamadham Mishra, M.D., from Wake Forest University Baptist Medical Center, in presentations this week at the American College of Rheumatology in Boston. view more (2007-11-12)
New insights into progressive hearing loss
In parallel studies in human and mouse, two groups of researchers have come to the same conclusion: that a new kind of gene is associated with progressive hearing loss. view more (2009-04-13)
Scientists shed light on inner workings of human embryonic stem cells
Scientists at UC Santa Barbara have made a significant discovery in understanding the way human embryonic stem cells function. view more (2009-05-01)
CSHL scientists identify and repress breast cancer stem cells in mouse tissue
By manipulating highly specific gene-regulating molecules called microRNAs, scientists at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue - cells that are widely thought to give rise to cancer. view more (2007-12-18)
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