Mitochondria Current Events | Mitochondria News | 3
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Protein sensor for fatty acid buildup in mitochondria
Just as homes have smoke detectors, cells have an enzyme that responds to a buildup of fatty acids by triggering the production of a key molecule in the biochemical pathway that breaks down these fatty acids, according to investigators at St. Jude Children's Research Hospital. view more (2007-02-15)
Yeast gives rise to new concept: cell fuel is 'brains' behind division
With the cost of diesel and gasoline getting nearer to the hourly minimum wage, too bad the fuel doesn't do more work - like deciding what route to take and pressing the gas pedal. view more (2008-04-28)
New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity
Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea? view more (2008-02-25)
UCLA chemists' study of protein may provide insights into heart disease and cancer
UCLA chemists studying a protein associated with a rare genetic disease may also be gaining insights into cancer and heart disease. view more (2006-08-11)
Kids with autism may have gene that causes muscle weakness
Some kids with autism may have a genetic defect that affects the muscles, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008. view more (2008-04-14)
Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT). view more (2006-07-25)
UCI discovers new Alzheimer's gene
A UC Irvine study has found that a gene called TOMM40 appears twice as often in people with Alzheimer's disease than in those without it. Alzheimer's, for which there is no cure, is the leading cause of elderly dementia. view more (2009-08-07)
Small molecule offers big hope against cancer
DCA is an odourless, colourless, inexpensive, relatively non-toxic, small molecule. And researchers at the University of Alberta believe it may soon be used as an effective treatment for many forms of cancer. view more (2007-01-17)
ABCB6 is key to production of heme in hemoglobin
Investigators at St. Jude Children's Research Hospital have discovered that a protein called ABCB6 plays a central role in production of a molecule that is key to the ability of red blood cells to carry oxygen, of liver cells to break down toxins, and of cells to extract energy from nutrients. view more (2006-09-29)
Nearly a century later, new findings support Warburg theory of cancer
German scientist Otto H. Warburg's theory on the origin of cancer earned him the Nobel Prize in 1931, but the biochemical basis for his theory remained elusive. view more (2009-01-12)
Gene may 'bypass' disease-linked mitochondrial defects, fly study suggests
By lending them a gene normally reserved for other classes of animals, researchers have shown they can rescue flies from their Parkinson's-like symptoms, including movement defects and excess free radicals produced in power-generating cellular components called mitochondria. view more (2009-05-06)
Obesity chokes up the cellular power plant
The machinery responsible for energy production in fat cells is working poorly as a result of obesity. Finnish research done at the University of Helsinki and the National Public Health Institute shows that this may aggravate and work to maintain the obese state in humans. view more (2008-03-13)
UF scientists reveal how dietary restriction cleans cells
Reduce, recycle and rebuild is as important to the most basic component of the human body, the cell, as it is to the environment. view more (2007-08-24)
Vitamin C supplements may reduce benefit from wide range of anti-cancer drugs
In pre-clinical studies, vitamin C appears to substantially reduce the effectiveness of anticancer drugs, say researchers at Memorial Sloan-Kettering Cancer Center. view more (2008-10-01)
Research reveals lipids' unexpected role in triggering death of brain cells
The lipid that accumulates in brain cells of individuals with an inherited enzyme disorder also drives the cell death that is a hallmark of the disease, according to new research led by St. Jude Children's Research Hospital investigators. view more (2009-11-13)
Cell's 'power plant' genes raise vision disorder risk
Genetic variation in the DNA of mitochondria - the "power plants" of cells - contributes to a person's risk of developing age-related macular degeneration (AMD), Vanderbilt investigators report May 7 in the journal PLoS ONE. view more (2008-05-07)
Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
Today, researchers report for the first time that genetic variants in mitochondria-energy-producing structures harboring DNA that are inherited only from the mother-are directly linked to metabolic markers for type 2 diabetes. view more (2007-08-13)
How mitochondria get their membranes bent
Mitochondria are the powerhouses of cells. Underneath their smooth surface they harbor an elaborately folded inner membrane. It holds a multitude of bottleneck like invaginations, which expand into elongated cavities (cristae). view more (2009-06-25)
Naturally fluorescent molecules may serve as cancer biomarker
Excess amounts of a naturally fluorescent molecule found in all living cells could serve as a natural biomarker for cancer, according to bioengineers. view more (2009-04-03)
Transcription factor protein's role in cell death, neurodegeneration and schizophrenia
Researchers at the University of Pennsylvania School of Medicine discovered that a protein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein -— typically active in the nucleus — could play a role in cell death and mitochondria-related diseases such as neurodegeneration and... view more... (2006-06-08)
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