Mitochondria Current Events | Mitochondria News | 5
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Diabetes treatment may lie in helping muscles to burn fat better
Scientists in Sydney and Melbourne have produced results that could silence the current debate about exactly how fat molecules clog up muscle cells, making them less responsive to insulin. view more (2009-01-28)
DNA repair mechanisms relocate in response to stress
Like doctors making house calls, some DNA repair enzymes can relocate to the part of the cell that needs their help, a collaborative team of scientists at Emory University School of Medicine has found. view more (2009-03-27)
Gladstone study links Alzheimer's with toxic protein fragments
New research from the Gladstone Institute of Neurological Disease details exactly how a mutant form of the protein apolipoprotein E, also known as apoE, is a causative factor for Alzheimer's disease. view more (2005-12-15)
Woolly mammoth genome comes to life
A McMaster University geneticist, in collaboration with genome researchers from Penn State University and the American Museum of Natural History has made history by mapping a portion of the woolly mammoth's genome. view more (2005-12-23)
Experts examine causes, treatment and prevention of glaucoma
Although scientists know progressive degeneration of retinal ganglion cells and their axons is the primary cause of glaucoma, researchers have yet to identify a way to stop or prevent the degeneration. view more (2009-03-05)
Research simplifies diagnosis of Charcot-Marie-Tooth disease
Hereditary Charcot-Marie-Tooth (CMT) disease strikes 1 in 2500 people. Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp are now demonstrating that mutations in mitofusin 2 are the major cause of CMT2, a specific type of the disease. view more (2006-07-25)
Zebrafish to shed light on human mitochondrial diseases
Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders. view more (2007-09-14)
First comprehensive paper on statins' adverse effects released
A paper co-authored by Beatrice Golomb, MD, PhD, associate professor of medicine at the University of California, San Diego School of Medicine and director of UC San Diego's Statin Study group cites nearly 900 studies on the adverse effects of HMG-CoA reductase inhibitors (statins), a class of drugs widely used to treat high cholesterol. view more (2009-01-27)
Oxygen triggered the evolution of complex life forms
Oxygen played a key role in the evolution of complex organisms, according to new research published in BMC Evolutionary Biology. The study shows that the complexity of life forms increased earlier than was thought, and in parallel with the availability of oxygen as an energy source. In the largest study to date that does not focus on vertebrates,... view more... (2004-01-22)
'Escaped' proteins add to hearing loss in elderly, UF researchers find
Age-related hearing loss is the most common sensory disorder among the elderly. But scientists are still trying to figure out what cellular processes govern or contribute to the loss. view more (2009-11-11)
Mitochondrial DNA sequencing tool updated
High-tech laboratory tools, like computers, are often updated publicly as their analytical capabilities expand. In the September issue of the Journal of Molecular Diagnostics, NIH grantees report they have developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that for the first time rapidly and reliably sequences... view more... (2006-08-28)
Research points to a new way to protect kidneys threatened by insufficient blood or toxins
Better treatments for acute renal failure may be possible by blocking the mitochondrial fragmentation that occurs when kidneys don't get enough blood or are exposed to toxins. view more (2009-05-19)
Mothers transmit DNA through daughters only
Scientists have argued whether or not the often-studied mitochondrial DNA molecule is clonally inherited. It is with assuming clonal inheritance this type of DNA has been used to track the origin of modern human as well as to draw pictures of genetic relationships among other animals and plants. The conflict has now been solved by two evolutionary... view more... (2001-09-06)
Penn study finds pro-death proteins required to regulate healthy immune function
Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells. view more (2007-08-13)
New test for mysterious metabolic diseases developed at Stanford/Packard
Scientists at Stanford University School of Medicine have devised a much-needed way to monitor and find treatments for a mysterious and devastating group of metabolic diseases that arise from mutations in cells' fuel-burning mechanism. view more (2009-02-11)
Monell researchers find metabolic defect in liver that can lead to obesity
Researchers at the Monell Chemical Senses Center have identified a genetically-transmitted metabolic defect that can lead to obesity in some individuals. view more (2007-07-25)
Agent orange chemical, dioxin, attacks the mitochondria to cause cancer, says Penn research team
Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression. view more (2007-12-18)
Forget the antioxidants? McGill researchers cast doubt on role of free radicals in aging
For more than 40 years, the prevailing explanation of why we get old has been tied to what is called oxidative stress. This theory postulates that when molecules like free radicals, oxygen ions and peroxides build up in cells, they overwhelm the cells' ability to repair the damage they cause, and the cells age. view more (2009-02-18)
Penn study finds a new role for RNA in human immune response
Researchers at the University of Pennsylvania School of Medicine have published the first study to test the role of RNA chemical modifications on immunity. view more (2005-08-24)
White blood cell uses DNA 'catapult' to fight infection
U.S. and Swiss scientists have made a breakthrough in understanding how a type of white blood cell called the eosinophil may help the body to fight bacterial infections in the digestive tract, according to research published online this week in Nature Medicine. view more (2008-08-14)
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