Mitochondria Current Events | Mitochondria News | 6
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Molecular differences between early and advanced melanomas could provide new drug targets
The cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found. view more (2007-03-13)
Mini heart attacks lessen damage from major ones
Researchers have discovered one potential mechanism by which briefly cutting off, then restoring, blood flow to arteries prior to a heart attack lessens the damage caused, according to a study published today in the journal Cardiovascular Research. view more (2008-12-02)
How appetite-stimulating brain cells work overtime during fasting
During periods of fasting, brain cells responsible for stimulating the appetite make sure that you stay hungry. Now, a new study of mice reported in the January issue of the journal Cell Metabolism, published by Cell Press, reveals the complex series of molecular events that keep those neurons active. view more (2007-01-03)
Investigational drug tested for preventing muscle fiber death in muscular dystrophy
An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage in Duchenne and other forms of muscular dystrophy (MD). view more (2008-03-17)
Long-term L-carnitine supplementation prevents development of liver cancer
A study will be published on March 21, 2009 in World Journal of Gastroenterology addresses the question. A research group in King Saud University, Kingdom of Saudi Arabia investigated, for the first time, the role of carnitine, a naturally occurring compound that is synthesized mainly in the liver, during the development of hepatocarcinogenesis. view more (2009-03-24)
New potential therapeutic target discovered for genetic disorder -- Barth syndrome
Researchers at NYU Langone Medical Center may have discovered a new targeted intervention for Barth Syndrome (BTHS). BTHS, a sometimes fatal disease, is a serious genetic disorder occurring predominantly in males that leads to infection or heart failure in childhood. view more (2009-03-03)
'Biggest ever' study of its kind may advance the treatment, diagnosis and prevention of Schizophrenia
Scientists at the Babraham Institute have made significant advances in understanding schizophrenia. Schizophrenia is a mental illness which has been estimated to affect over 1% of the population and costs the NHS over £2.5 billion per year. Babraham scientists have pinpointed a breakdown in mitochondria - the power stations of the cell - as... view more... (2004-08-12)
Decoded gene sequence of the diatom Thalassiosira pseudonana
For the very first time, the genetic make-up of a planktonic marine alga has been sequenced. During this process, a team of international scientists found unexpected metabolic pathways in the diatom Thalassiosira pseudonana. The results will be published in the scientific journal 'Science' this week. view more (2004-10-01)
PINK1 protects from Parkinson's
Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons. view more (2007-06-19)
Burnham Researchers Turn Cancer Friend into Cancer Foe
Burnham Institute for Medical Research today announced that scientists have created a peptide that binds to Bcl-2, a protein that protects cancer cells from programmed cell death, and converts it into a cancer cell killer. view more (2008-10-08)
Abnormal fat metabolism underlies heart problems in diabetic patients
Heart disease hits people with diabetes twice as often as people without diabetes. In those with diabetes, cardiovascular complications occur at an earlier age and often result in premature death, making heart disease the major killer of diabetic people. But why is heart disease so prevalent among diabetics? view more (2007-08-13)
Antioxidant found in many foods and red wine is potent and selective killer of leukemia cells
A naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells in culture while showing no discernible toxicity against healthy cells. view more (2007-04-24)
Structure of cog at the hub of metabolism reveals anti-ageing function
The structure of a key energy-releasing enzyme found in all animals is designed to minimise free radical production, an international team of researchers report in the journal Science today. In a startling feat of structural biology, the team visualised the entire molecular structure of succinate dehydrogenase in the bacterium E. coli, allowing... view more... (2003-01-30)
DNA provides 'smoking gun' in the case of the missing songbirds
It sounds like a tale straight from "CSI": The bully invades a home and does away with the victim, then is ultimately found out with the help of DNA evidence. view more (2008-11-05)
Scattered light rapidly detects tumor response to chemotherapy
New technology developed by Duke University bioengineers can help clinicians more precisely detect whether specific cancer drugs are working, and should give basic researchers a powerful new tool to better understand the underlying mechanisms of cancer development. view more (2009-02-02)
Rising ocean temperatures, pollution have oysters in hot water
Oysters exposed to high water temperatures and a common heavy metal are unable to obtain sufficient oxygen and convert it to cellular energy. view more (2006-10-11)
Glucose triggers brain cell death in rats after hypoglycemic coma
Brain damage that was thought to be caused by hypoglycemic coma actually occurs when glucose is administered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical Center. view more (2007-04-05)
Mayo researchers look for explanation behind high incidence of diabetes among Asian Indians
The incidence of type 2 diabetes is rising, especially in urbanized parts of the world where sedentary lifestyles and obesity abound. In addition to weight and inactivity, race puts some people at increased risk for developing type 2 diabetes. view more (2008-03-03)
Ketogenic diet prevents seizures by enhancing brain energy production, increasing neuron stability
Although the high-fat, calorie-restricted ketogenic diet (KD) has long been used to prevent childhood epileptic seizures that are unresponsive to drugs, physicians have not really understood exactly why the diet works. view more (2005-11-14)
Features of replication suggest viruses have common themes, vulnerabilities
A study of the reproductive apparatus of a model virus is bolstering the idea that broad classes of viruses - including those that cause important human diseases such as AIDS, SARS and hepatitis C - have features in common that could eventually make them vulnerable to broad-spectrum antiviral agents. view more (2007-08-14)
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