Mitochondria Current Events | Mitochondria News | 7
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Researchers engineer metabolic pathway in mice to prevent diet-induced obesity
In recent years, obesity has taken on epidemic proportions in developed nations, contributing significantly to major medical problems, early death and rising health care costs. view more (2009-06-03)
Pretreating rogue cancer cells with aspirin cripples their resistance to targeted therapy
For years, we have heard about the health benefits of taking low doses of aspirin - preventing everything from Alzheimer's disease to heart attacks and stroke. view more (2005-12-13)
How oxidative stress may help prolong life
Oxidative stress has been linked to aging, cancer and other diseases in humans. Paradoxically, researchers have suggested that small exposure to oxidative conditions may actually offer protection from acute doses. view more (2009-05-29)
St. Jude researchers find key step in programmed cell death
Investigators at St. Jude Children's Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process. view more (2008-03-03)
Ginkgo biloba extract: More than just for memory?
Researchers at Georgetown University Medical Center say they now have a clearer picture of how an extract from the leaves of the Ginkgo biloba tree reduces the risk of aggressive cancer in animal experiments. view more (2006-02-24)
CU-Boulder worm study sheds light on human aging, inherited diseases
Microscopic worms used for scientific research are living longer despite cellular defects, a discovery that is shedding light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases. view more (2007-10-02)
First research to show that diabetes damages DNA in men's sperm and may affect fertility
Scientists have found that sperm from diabetic men have greater levels of DNA damage than sperm from men who do not have the disease. They warn that such DNA damage might affect a man's fertility. view more (2007-05-03)
Anti-aging hormone reduces reactive oxygen species
Scientists recently discovered an anti-aging hormone called Klotho. Now, a new study shows that this protein acts by increasing the cell's ability to detoxify harmful reactive oxygen species. view more (2005-11-04)
History-hunting geneticists can still follow familiar trail
As the world's first explorers branched away from humanity's birthplace in east Africa some 65,000 years ago, distinct mutations accumulated in the DNA of each population, essentially providing a genetic trail for modern researchers to follow. view more (2006-12-20)
New findings shed light to the mechanisms of Parkinson's disease
The findings of Finnish scientists with their multinational collaborators shed light to the mechanisms of Parkinson's disease and early menopause. view more (2004-09-07)
Drug compound leads to death of ovarian cancer cells resistant to chemotherapy
In a discovery that may be useful for maintaining remission in chemo-resistant ovarian cancer, Yale scientists report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovarian cancer cells by halting the activation of a protein pathway called mTOR. view more (2008-04-18)
Proteins are key to cell death in heart disease, stroke and degenerative conditions
Researchers at Yale School of Medicine have gained deeper understanding of two members of a family of proteins called caspases that play a key role in promoting apoptosis, a process in which the cell responds to external signals by essentially committing suicide. view more (2006-02-23)
Researchers discover how antibiotic inhibits bacterial growth
Researchers at the University of Illinois at Chicago, in collaboration with research teams from Pharmacia & Upjohn and Pfizer, have discovered precisely how the antibiotic linezolid inhibits bacterial growth. view more (2007-05-11)
Marathon mice elucidate little-known muscle type
Researchers report in the January issue of the journal Cell Metabolism, published by Cell Press, the discovery of a genetic "switch" that drives the formation of a poorly understood type of muscle. Moreover, they found, animals whose muscles were full of the so-called IIX fibers were able to run farther and at higher work loads than... view more... (2007-01-03)
Genetic mutation causes familial susceptibility for degenerative brain disease
Mutation of a gene that helps proteins migrate in and out of the cell's genetic command center - the nucleus - puts some families at higher risk for the degenerative brain disease acute necrotizing encephalopathy (ANE). view more (2009-01-07)
Chemosensitivity of cancer cells depends on their protein dependency
Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. The study will be published online October 26, 2009 and in the November 2, 2009 print issue of the Journal of Cell Biology (JCB). view more (2009-10-26)
Common bacteria activating natural killer T cells may cause autoimmune liver disease
A bacteria commonly found in soil and water triggered autoimmune symptoms in mice similar to those found in an incurable liver disease called Primary Biliary Cirrhosis (PBC). view more (2008-05-15)
Domesticated pig's wild origin mapped
Scientists at Uppsala University and the Swedish University for Agricultural Sciences have been participating in an international collaborative project to map the wild origins of the domesticated pig. The findings show that the wild boar was domesticated several times in different parts of Europe and Asia. The study is being presented in the... view more... (2005-03-11)
MNI researchers find a new role for mitochondria in cellular copper regulation
Copper is an essential part of our lives. From copper pipes and wires - to important copper-containing proteins in the body, copper is necessary for healthy growth and neurological development. view more (2007-05-02)
Developmental drug may help bone fractures heal after radiation exposure
A drug currently under development by the University of Pittsburgh School of Medicine may help bone fractures heal more quickly after radiation exposure, according to a study by Pitt researchers. view more (2009-11-03)
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