Mitochondrial Current Events | Mitochondrial News | 2
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New DNA study helps explain unique diversity among melanesians
Small populations of Melanesians — among the most genetically diverse people on the planet — have significant differences in their mitochondrial DNA that can be linked to where they live, the size of their home island and the language they speak. view more (2007-02-28)
How mitochondrial gene defects impair respiration, other major life functions
Researchers are delving into abnormal gene function in mitochondria, structures within cells that power our lives. Mitochondria are the place where energy is generated from the most basic molecules of food. Because this function is essential to life, defects in mitochondria may affect a wide range of organ systems in humans and animals. view more (2009-09-25)
Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT). view more (2006-07-25)
Research points to a new way to protect kidneys threatened by insufficient blood or toxins
Better treatments for acute renal failure may be possible by blocking the mitochondrial fragmentation that occurs when kidneys don't get enough blood or are exposed to toxins. view more (2009-05-19)
Role for CISD2 gene in human disease and lifespan control
In the May 15th issue of G&D, Dr. Ting-Fen Tsai (The National Yang-Ming University, Taiwan) and colleagues present a new animal model of human Wolfram Syndrome, and effectively link CISD2 gene function, mitochondrial integrity and aging in mammals. view more (2009-05-15)
Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection
As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease. view more (2008-04-07)
White blood cell uses DNA 'catapult' to fight infection
U.S. and Swiss scientists have made a breakthrough in understanding how a type of white blood cell called the eosinophil may help the body to fight bacterial infections in the digestive tract, according to research published online this week in Nature Medicine. view more (2008-08-14)
Key event in cell death occurs as single, quick event
Scientists at St. Jude Children's Research Hospital have demonstrated that a key event during apoptosis (cell suicide) occurs as a single, quick event, rather than as a step-by-step process. view more (2006-08-02)
Scientists present the largest-to-date genetic snapshot of Iceland 1,000 years ago
Scientists at deCODE genetics have completed the largest study of ancient DNA from a single population ever undertaken. Analyzing mitochondrial DNA, which is passed from mother to offspring, from 68 skeletal remains, the study provides a detailed look at how a contemporary population differs from that of its ancestors. view more (2009-01-16)
Study finds a high caloric diet may prevent the progression of amyotrophic lateral sclerosis
A recent study directed by the Mount Sinai School of Medicine suggests a ketogenic- high caloric diet may prevent the progression of Amyotrophic Lateral Sclerosis (ALS). view more (2006-04-18)
Penn study finds a new role for RNA in human immune response
Researchers at the University of Pennsylvania School of Medicine have published the first study to test the role of RNA chemical modifications on immunity. view more (2005-08-24)
Nearly a century later, new findings support Warburg theory of cancer
German scientist Otto H. Warburg's theory on the origin of cancer earned him the Nobel Prize in 1931, but the biochemical basis for his theory remained elusive. view more (2009-01-12)
Study looks at mitochondrial variation in sperm traits and sperm competitive ability
University of Nevada, Reno researchers Jeanne and David Zeh of the Department of Biology have received a five-year, $650,000 grant from the National Science Foundation to investigate the effects of natural mitochondrial variation on sperm traits and sperm competitive ability. view more (2007-09-20)
Nerve cells' power plants caught in a traffic jam
Nerve cells need lots of energy to work properly, and the energy needs to be delivered to the right place at the right time. By inducing a mutation in fruit flies, researchers have figured out that a particular gene governs the movement of cells' energy-producing units, called mitochondria. view more (2005-08-05)
Unstable proteins can cause premature ageing
The normal ageing process has long been linked to problems with cell respiration, the process through which the cells extract energy from nutrients. view more (2009-08-06)
Small molecule offers big hope against cancer
DCA is an odourless, colourless, inexpensive, relatively non-toxic, small molecule. And researchers at the University of Alberta believe it may soon be used as an effective treatment for many forms of cancer. view more (2007-01-17)
Preventing spinal cord injury during aortic surgery
Surgery to repair aortic aneurysms often comes with a high price: neurological deficits, but new research points to a possible defense against spinal cord injury during aortic surgery. view more (2006-06-22)
Lifestyle can alter gene activity, lead to insulin resistance
A Finnish study of identical twins has found that physical inactivity and acquired obesity can impair expression of the genes which help the cells produce energy. view more (2008-06-19)
Zebrafish to shed light on human mitochondrial diseases
Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders. view more (2007-09-14)
How mitochondria get their membranes bent
Mitochondria are the powerhouses of cells. Underneath their smooth surface they harbor an elaborately folded inner membrane. It holds a multitude of bottleneck like invaginations, which expand into elongated cavities (cristae). view more (2009-06-25)
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