Mitochondrial Current Events | Mitochondrial News | 3
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DNA provides 'smoking gun' in the case of the missing songbirds
It sounds like a tale straight from "CSI": The bully invades a home and does away with the victim, then is ultimately found out with the help of DNA evidence. view more (2008-11-05)
Iberia was the European demographic reservoir during the last Ice Age
By studying mitochondrial DNA, which is passed from mother to child, researchers have found that most of the actual European inhabitants seem to have come from re-expansion of hunter-gatherers populations, which have migrated from Iberia, Europe after the end of the last Ice Age reports an article in the January issue of Genome Research. view more (2005-01-12)
Promising novel treatment for human cancer -- Chrysanthemum indicum extract
A series of studies have demonstrated that Chrysanthemum indicum possesses antimicrobial, antiinflammatory, immunomodulatory, and neuroprotective effects. view more (2009-10-16)
HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection
Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress... view more... (2009-03-26)
New test for mysterious metabolic diseases developed at Stanford/Packard
Scientists at Stanford University School of Medicine have devised a much-needed way to monitor and find treatments for a mysterious and devastating group of metabolic diseases that arise from mutations in cells' fuel-burning mechanism. view more (2009-02-11)
First comprehensive paper on statins' adverse effects released
A paper co-authored by Beatrice Golomb, MD, PhD, associate professor of medicine at the University of California, San Diego School of Medicine and director of UC San Diego's Statin Study group cites nearly 900 studies on the adverse effects of HMG-CoA reductase inhibitors (statins), a class of drugs widely used to treat high cholesterol. view more (2009-01-27)
A new brake on cellular energy production discovered
A condition that has to be met for the body to be able to keep warm, move and even survive is that the mitochondria - the cells' power stations - release the right amounts of energy. view more (2007-07-27)
Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia
Researchers at the University Hospital of Magdeburg (Germany) have discovered that atrial tachycardia is associated with mitochondrial dysfunction and oxidative stress followed by the activation of the NF-kB signalling pathway with induction of NF-kB target gene expression in atrial tissue. view more (2008-04-24)
Exercise reverses aging in human skeletal muscle
Not only does exercise make most people feel better and perform physical tasks better, it now appears that exercise - specifically, resistance training -- actually rejuvenates muscle tissue in healthy senior citizens. view more (2007-05-23)
OHSU research reveals possible future target for delaying or stopping Alzheimer's
Researchers at Oregon Health & Science University's Neurological Sciences Institute (NSI) have located a possible target for future therapies aimed at delaying or stopping Alzheimer's disease. view more (2006-05-02)
Press release ANRS, INSERM, AFSSAPS
Adverse events that were unknown so far, have recently been observed in France in children who had been exposed to antiretroviral drugs (nucleosidic inhibitors of the reverse transcriptase) during intra uterine life and postnatally to prevent mother to child transmission of HIV. The children suffer from mitochondrial dysfunctions. The mitochondry... view more... (1999-06-25)
New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity
Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea? view more (2008-02-25)
Mitochondrial DNA sequencing tool updated
High-tech laboratory tools, like computers, are often updated publicly as their analytical capabilities expand. In the September issue of the Journal of Molecular Diagnostics, NIH grantees report they have developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that for the first time rapidly and reliably sequences... view more... (2006-08-28)
First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown
In a paper being presented in two American Physiological Society sessions at Experimental Biology 2006, a joint Estonian-French team demonstrated "for the first time that mitochondria are able to induce nuclear deformation, suggesting that mitochondria may mechanically regulate nuclear function." view more (2006-04-03)
A potent and selective anti-tumor agent on human gastric cancer
A research article to be published on June 21, 2009 in the World Journal of Gastroenterology addresses this question. view more (2009-06-29)
Naturally fluorescent molecules may serve as cancer biomarker
Excess amounts of a naturally fluorescent molecule found in all living cells could serve as a natural biomarker for cancer, according to bioengineers. view more (2009-04-03)
CU-Boulder worm study sheds light on human aging, inherited diseases
Microscopic worms used for scientific research are living longer despite cellular defects, a discovery that is shedding light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases. view more (2007-10-02)
Descartes Research Prize to Professor Jacobs from the University of Tampere
At a ceremony today in Prague Castle, Howy Jacobs, Professor of Molecular Biology in the University of Tampere (Finland), was presented with the EU's Descartes Research Prize 2004, on behalf of his multinational research consortium on 'Mitochondrial Biogenesis, Ageing and Disease' (MBAD). view more (2004-12-02)
Gene mutation responsible for premature skin aging disease identified
In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome." view more (2009-09-01)
Coding for arthropods-what's so special about insects and spiders?
The central dogma of molecular biology is that DNA makes RNA makes protein. This relies on a specific underlying code which relates given triplets of RNA nucleotides into specific amino acids. view more (2006-04-25)
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