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Topical Papers in Biochemical Journal - Selective determination of mitochandrial chelatable iron in viable cells with a new fluorescent sensor
This paper by Petrat and colleagues marks an important advance in our understanding of the regulation of iron in the human body. Real-time changes in the concentration of the ionized form of iron (Fe2+) can now be monitored within the mitochondria of living cells for the first time, thanks to the technique described in this article. For some... view more... (2002-02-08)

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor
University of Utah researchers and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumor called paraganglioma (PGL).   view more (2009-07-24)

Yeast gives rise to new concept: cell fuel is 'brains' behind division
With the cost of diesel and gasoline getting nearer to the hourly minimum wage, too bad the fuel doesn't do more work - like deciding what route to take and pressing the gas pedal.   view more (2008-04-28)

Researchers develop marker that identifies energy-producing centers in nerve cells
A protein that causes coral to glow is helping researchers at the University of Maryland School of Medicine to light up brain cells that are critical for the proper functioning of the central nervous system.   view more (2007-02-02)

History-hunting geneticists can still follow familiar trail
As the world's first explorers branched away from humanity's birthplace in east Africa some 65,000 years ago, distinct mutations accumulated in the DNA of each population, essentially providing a genetic trail for modern researchers to follow.   view more (2006-12-20)

Researchers posit new ideas about human migration from Asia to Americas
Questions about human migration from Asia to the Americas have perplexed anthropologists for decades, but as scenarios about the peopling of the New World come and go, the big questions have remained.   view more (2007-10-26)

Lactic acid not athlete's poison, but an energy source-if you know how to use it
In the lore of marathoners and extreme athletes, lactic acid is poison, a waste product that builds up in the muscles and leads to muscle fatigue, reduced performance and pain.   view more (2006-04-20)

Clues to future evolution of HIV come from African green monkeys
Monkey viruses related to HIV may have swept across Africa more recently than previously thought, according to new research from The University of Arizona in Tucson.   view more (2007-07-17)

Neutral evolution has helped shape our genome
Johns Hopkins researchers have added to the growing mound of evidence that many of the genetic bits and pieces that drive evolutionary changes do not confer any advantages or disadvantages to humans or other animals.   view more (2007-07-10)

Sidestepping cancer's chaperone
Cancerous tumors are wildly unfavorable environments. Struggling for oxygen and nutrients while being bombarded by the body's defense systems, tumor cells in fact require sophisticated adaptations to survive and grow.   view more (2007-10-22)

Woolly-Mammoth Gene Study Changes Extinction Theory
A large genetic study of the extinct woolly mammoth has revealed that the species was not one large homogenous group, as scientists previously had assumed, and that it did not have much genetic diversity.   view more (2008-06-12)

Asian populations less likely to get relief from chest pain with nitroglycerin
Nitroglycerin, also called glyceryl trinitrate (GTN), has been widely used for the management of coronary heart disease, specifically angina and heart failure, for more than 130 years.   view more (2006-01-27)

Scientists sequence DNA of woolly mammoth
Experts in ancient DNA from McMaster University (Canada) have teamed up with genome researchers from Penn State University (USA) for the investigation of permafrost bone samples from Siberia.   view more (2005-12-20)

The first men and women from the Canary Islands were Berbers
A team of Spanish and Portuguese researchers has carried out molecular genetic analysis of the Y chromosome (transmitted only by males) of the aboriginal population of the Canary Islands to determine their origin and the extent to which they have survived in the current population.   view more (2009-10-22)

Lemurs' fur color may not define species
Different coat colour might not correspond to different species for nocturnal lemurs. In a study published today in the open access journal BMC Evolutionary Biology, researchers find that lemurs that appeared to belong to different species because they have strikingly different coat colours, are in fact genetically related and belong to the same... view more... (2006-11-16)

Three new species of lemurs identified
Researchers have identified three new species of lemurs, the small, big-eyed primates native to the island of Madagascar.   view more (2006-02-23)

Rodent's bizarre traits deepen mystery of genetics, evolution
A shadowy rodent has potential to shed light on human genetics and the mysteries of evolution.   view more (2006-09-18)

UCI discovers new Alzheimer's gene
A UC Irvine study has found that a gene called TOMM40 appears twice as often in people with Alzheimer's disease than in those without it. Alzheimer's, for which there is no cure, is the leading cause of elderly dementia.   view more (2009-08-07)

Researchers find connection between caloric restriction and longevity
For nearly 70 years scientists have known that caloric restriction prolongs life. In everything from yeast to primates, a significant decrease in calories can extend lifespan by as much as one-third. But getting under the hood of the molecular machinery that drives this longevity has remained elusive.   view more (2007-09-21)

New study shows how spikes in nitrite can have
A new study provides insight into how a short burst in nitrite can exert lasting beneficial effects on the heart, protecting it from stress and assaults such as heart attacks.   view more (2009-03-04)
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