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Few clues about African ancestry to be found in mitochondrial DNA
Mitochondrial DNA may not hold the key to your origins after all. A study published today in the open access journal BMC Biology reveals that fewer than 10% of African American mitochondrial DNA sequences analysed can be matched to mitochondrial DNA from one single African ethnic group.   view more (2006-10-12)

Reduced mitochondrial function important mechanism in aging
Scientists at the Karolinska Institute have found that changes in the "powerhouse" of cells, the mitochondria, play a key role in aging. The findings are being published in this week's issue of the journal Nature. Mitochondria, which provide energy to cells, have their own set of DNA.... view more (2004-05-27)

Mothers transmit DNA through daughters only
Scientists have argued whether or not the often-studied mitochondrial DNA molecule is clonally inherited. It is with assuming clonal inheritance this type of DNA has been used to track the origin of modern human as well as to draw pictures of genetic relationships among other animals and plants.... view more (2001-09-06)

New findings shed light to the mechanisms of Parkinson's disease
The findings of Finnish scientists with their multinational collaborators shed light to the mechanisms of Parkinson's disease and early menopause.   view more (2004-09-07)

Large reservoir of mitochondrial DNA mutations identified in humans
Researchers at the University of Newcastle, England, and the Virginia Bioinformatics Institute at Virginia Tech in the United States have revealed a large reservoir of mitochondrial DNA mutations present in the general population.   view more (2008-08-12)

Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
Today, researchers report for the first time that genetic variants in mitochondria-energy-producing structures harboring DNA that are inherited only from the mother-are directly linked to metabolic markers for type 2 diabetes.   view more (2007-08-13)

New DNA study helps explain unique diversity among melanesians
Small populations of Melanesians — among the most genetically diverse people on the planet — have significant differences in their mitochondrial DNA that can be linked to where they live, the size of their home island and the language they speak.   view more (2007-02-28)

White blood cell uses DNA 'catapult' to fight infection
U.S. and Swiss scientists have made a breakthrough in understanding how a type of white blood cell called the eosinophil may help the body to fight bacterial infections in the digestive tract, according to research published online this week in Nature Medicine.   view more (2008-08-14)

Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT).   view more (2006-07-25)

DNA provides 'smoking gun' in the case of the missing songbirds
It sounds like a tale straight from "CSI": The bully invades a home and does away with the victim, then is ultimately found out with the help of DNA evidence.   view more (2008-11-05)

Cell's 'power plant' genes raise vision disorder risk
Genetic variation in the DNA of mitochondria - the "power plants" of cells - contributes to a person's risk of developing age-related macular degeneration (AMD), Vanderbilt investigators report May 7 in the journal PLoS ONE.   view more (2008-05-07)

Iberia was the European demographic reservoir during the last Ice Age
By studying mitochondrial DNA, which is passed from mother to child, researchers have found that most of the actual European inhabitants seem to have come from re-expansion of hunter-gatherers populations, which have migrated from Iberia, Europe after the end of the last Ice Age reports an article... view more (2005-01-12)

Mitochondrial genes move to the nucleus
Why mitochondrial genes ditch their cushy haploid environs to take up residence in a large and chaotic nucleus has long stumped evolutionary biologists, but Indiana University Bloomington scientists report in this week's Science that they've uncovered an important clue in flowering plants.   view more (2007-03-23)

DNA analysis reveals rapid population shift among Pleistocene cave bears
Studying DNA obtained from teeth of ancient cave bears, researchers have been able to identify a shift in a particular population of the bears inhabiting a European valley in the late Pleistocene era.   view more (2007-02-20)

PINK1 protects from Parkinson's
Parkinson disease (PD) is a common neurodegenerative disease characterized by the selective loss of midbrain dopaminergic neurons.   view more (2007-06-19)

The fight against obesity -- a new insight
With obesity still on the increase, it appears that the main weapon in the fight against it - reducing energy consumption by eating less - is ineffective.   view more (2008-03-12)

Preventing spinal cord injury during aortic surgery
Surgery to repair aortic aneurysms often comes with a high price: neurological deficits, but new research points to a possible defense against spinal cord injury during aortic surgery.   view more (2006-06-22)

New research helps explain genetics of Parkinson's disease
A new study by Narendra et al. suggests that Parkin, the product of the Parkinson's disease-related gene Park2, prompts neuronal survival by clearing the cell of its damaged mitochondria.   view more (2008-11-24)

Mitochondrial DNA sequencing tool updated
High-tech laboratory tools, like computers, are often updated publicly as their analytical capabilities expand. In the September issue of the Journal of Molecular Diagnostics, NIH grantees report they have developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that... view more (2006-08-28)

Back to the future: Mastodon extends the time limit on DNA sequencing
In a new paper in the open access journal PLoS Biology, Michael Hofreiter from the Max Planck Institute for Evolutionary Anthropology in Germany, and colleagues from Switzerland and the United States, announce the sequencing of the complete mitochondrial genome of the mastodon (Mammut americanum),... view more (2007-07-24)

Key event in cell death occurs as single, quick event
Scientists at St. Jude Children's Research Hospital have demonstrated that a key event during apoptosis (cell suicide) occurs as a single, quick event, rather than as a step-by-step process.   view more (2006-08-02)

New research may lead to earlier diagnosis and treatment of primary biliary cirrhosis in families
Mayo Clinic researchers have found that first-degree relatives (i.e., parents, siblings, children) of patients with primary biliary cirrhosis (PBC) are more likely to have the biomarker of the disease in their blood.   view more (2007-09-11)

CU-Boulder worm study sheds light on human aging, inherited diseases
Microscopic worms used for scientific research are living longer despite cellular defects, a discovery that is shedding light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases.   view more (2007-10-02)

Study looks at mitochondrial variation in sperm traits and sperm competitive ability
University of Nevada, Reno researchers Jeanne and David Zeh of the Department of Biology have received a five-year, $650,000 grant from the National Science Foundation to investigate the effects of natural mitochondrial variation on sperm traits and sperm competitive ability.   view more (2007-09-20)

DNA solves mystery of Gibraltar's macaques
Research will help manage populations of macaques, a threatened species of primate   view more (2005-04-20)

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