Mitochondrial Dna Current Events | Mitochondrial Dna News | 2
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Preventing spinal cord injury during aortic surgery
Surgery to repair aortic aneurysms often comes with a high price: neurological deficits, but new research points to a possible defense against spinal cord injury during aortic surgery. view more (2006-06-22)
New research helps explain genetics of Parkinson's disease
A new study by Narendra et al. suggests that Parkin, the product of the Parkinson's disease-related gene Park2, prompts neuronal survival by clearing the cell of its damaged mitochondria. view more (2008-11-24)
Mitochondrial DNA sequencing tool updated
High-tech laboratory tools, like computers, are often updated publicly as their analytical capabilities expand. In the September issue of the Journal of Molecular Diagnostics, NIH grantees report they have developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that for the first time rapidly and reliably sequences... view more... (2006-08-28)
UMMS researchers publish DNA identification of czar's children
Cutting edge science has finally put to rest a 90-year-old mystery that involved nobility, revolution, murder and the long-romanticized story of a child's escape from the firing squad. Genomic analysis performed at the University of Massachusetts Medical School in cooperation with Institutions of Russian Academy of Science (VIGG) and Academy of... view more... (2009-02-26)
Unstable proteins can cause premature ageing
The normal ageing process has long been linked to problems with cell respiration, the process through which the cells extract energy from nutrients. view more (2009-08-06)
Back to the future: Mastodon extends the time limit on DNA sequencing
In a new paper in the open access journal PLoS Biology, Michael Hofreiter from the Max Planck Institute for Evolutionary Anthropology in Germany, and colleagues from Switzerland and the United States, announce the sequencing of the complete mitochondrial genome of the mastodon (Mammut americanum), a recently extinct relative of the living... view more... (2007-07-24)
Stress signals link pre-existing sickness with susceptibility to bacterial infection
Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tract. view more (2009-07-28)
Key event in cell death occurs as single, quick event
Scientists at St. Jude Children's Research Hospital have demonstrated that a key event during apoptosis (cell suicide) occurs as a single, quick event, rather than as a step-by-step process. view more (2006-08-02)
New research may lead to earlier diagnosis and treatment of primary biliary cirrhosis in families
Mayo Clinic researchers have found that first-degree relatives (i.e., parents, siblings, children) of patients with primary biliary cirrhosis (PBC) are more likely to have the biomarker of the disease in their blood. view more (2007-09-11)
Discovery of genetic mutation in Leigh syndrome
Researchers at the Montreal Neurological Institute and Hospital (The Neuro), McGill University have discovered a genetic mutation underlying late-onset Leigh syndrome, a rare inherited metabolic disorder characterized by the degeneration of the central nervous system. view more (2009-08-11)
CU-Boulder worm study sheds light on human aging, inherited diseases
Microscopic worms used for scientific research are living longer despite cellular defects, a discovery that is shedding light on how the human body ages and how doctors could one day limit or reverse genetic mutations that cause inherited diseases. view more (2007-10-02)
Study looks at mitochondrial variation in sperm traits and sperm competitive ability
University of Nevada, Reno researchers Jeanne and David Zeh of the Department of Biology have received a five-year, $650,000 grant from the National Science Foundation to investigate the effects of natural mitochondrial variation on sperm traits and sperm competitive ability. view more (2007-09-20)
DNA solves mystery of Gibraltar's macaques
Research will help manage populations of macaques, a threatened species of primate view more (2005-04-20)
A new brake on cellular energy production discovered
A condition that has to be met for the body to be able to keep warm, move and even survive is that the mitochondria - the cells' power stations - release the right amounts of energy. view more (2007-07-27)
A link between mitochondria and tumor formation in stem cells
Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -a cell's energy makers. Stem cells with more active mitochondria also have a greater capacity to differentiate and are more likely to form tumors. view more (2008-10-13)
Bad mitochondria may actually be good for you
Mice with a defective mitochondrial protein called MCLK1 produce elevated amounts of reactive oxygen when young; that should spell disaster, yet according to a study in this week's JBC these mice actually age at a slower rate and live longer than normal mice. view more (2009-07-23)
Kids with autism may have gene that causes muscle weakness
Some kids with autism may have a genetic defect that affects the muscles, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008. view more (2008-04-14)
How mitochondrial gene defects impair respiration, other major life functions
Researchers are delving into abnormal gene function in mitochondria, structures within cells that power our lives. Mitochondria are the place where energy is generated from the most basic molecules of food. Because this function is essential to life, defects in mitochondria may affect a wide range of organ systems in humans and animals. view more (2009-09-25)
Scientists sequence DNA of woolly mammoth
Experts in ancient DNA from McMaster University (Canada) have teamed up with genome researchers from Penn State University (USA) for the investigation of permafrost bone samples from Siberia. view more (2005-12-20)
First comprehensive paper on statins' adverse effects released
A paper co-authored by Beatrice Golomb, MD, PhD, associate professor of medicine at the University of California, San Diego School of Medicine and director of UC San Diego's Statin Study group cites nearly 900 studies on the adverse effects of HMG-CoA reductase inhibitors (statins), a class of drugs widely used to treat high cholesterol. view more (2009-01-27)
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