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Mitochondrial Dna Current Events | Mitochondrial Dna News | 4

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Promising novel treatment for human cancer -- Chrysanthemum indicum extract
A series of studies have demonstrated that Chrysanthemum indicum possesses antimicrobial, antiinflammatory, immunomodulatory, and neuroprotective effects.   view more (2009-10-16)

DNA barcodes put to the test
With species around the world disappearing faster than biologists can identify them, many scientists pinned their hopes on DNA barcoding, a recently proposed strategy that treats a short fragment of DNA as a sort of universal product code to identify species.   view more (2005-11-29)

Gene mutation responsible for premature skin aging disease identified
In the new print issue of Nature Genetics, scientists in Singapore and Germany report that mutations in the PYCR1 gene cause the rare genetic condition that results in premature skin aging and that is known as "wrinkly skin syndrome."   view more (2009-09-01)

HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection
Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress... view more... (2009-03-26)

Obesity genetics
New evidence that genetics plays a key role in obesity is published today in the International Journal of Bioinformatics Research and Applications. The findings relate to the genetics of modern Pima Indians who have an unusually high rate of obesity but could be extrapolated to all people.   view more (2007-10-16)

Rodent's bizarre traits deepen mystery of genetics, evolution
A shadowy rodent has potential to shed light on human genetics and the mysteries of evolution.   view more (2006-09-18)

Woolly-Mammoth Gene Study Changes Extinction Theory
A large genetic study of the extinct woolly mammoth has revealed that the species was not one large homogenous group, as scientists previously had assumed, and that it did not have much genetic diversity.   view more (2008-06-12)

Scientists discover ancient protein and DNA sequences in same fossil
For the first time in the world, researchers at the University of Newcastle upon Tyne, UK, along with collaborators at the University of Oxford, Harvard University, and Michigan State University have uncovered two genetically informative molecules from a single fossil bone. In addition to the recovery of mitochondrial DNA, the complete sequencing... view more... (2002-11-12)

Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)

A better way to copy DNA
Scientists have developed a new method for DNA amplification that could replace the polymerase chain reaction (PCR), a technique that is invaluable for both medical diagnostics and basic research but which is confined to the laboratory. In the August issue of EMBO reports, Huimin Kong and colleagues at New England Biolabs (Beverly, MA, USA)... view more... (2004-07-14)

Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia
Researchers at the University Hospital of Magdeburg (Germany) have discovered that atrial tachycardia is associated with mitochondrial dysfunction and oxidative stress followed by the activation of the NF-kB signalling pathway with induction of NF-kB target gene expression in atrial tissue.   view more (2008-04-24)

Exercise reverses aging in human skeletal muscle
Not only does exercise make most people feel better and perform physical tasks better, it now appears that exercise - specifically, resistance training -- actually rejuvenates muscle tissue in healthy senior citizens.   view more (2007-05-23)

Damage from oxygen may be one cause of Parkinson's disease
Research by neuroscientists at the University of Virginia Health System shows that oxygen free radicals are damaging proteins in mitochondria, the tiny cellular 'batteries' of brain cells.   view more (2006-05-17)

Study finds DNA barcoding requires caution without closer examination
The goal of DNA barcoding is to find a simple, cheap, and rapid DNA assay that can be converted to a readily accessible technical skill that bypasses the need to rely on highly trained taxonomic specialists for identifications of the world's biota.   view more (2009-06-25)

Genetics behind developmental brain disorders may play a wider role with congenital diseases
Findings of a recent genetic study on developmental brain disorders may be the "tip of an iceberg" revealing factors involved with a number of congenital diseases, according to UC Irvine researchers.   view more (2006-07-07)

OHSU research reveals possible future target for delaying or stopping Alzheimer's
Researchers at Oregon Health & Science University's Neurological Sciences Institute (NSI) have located a possible target for future therapies aimed at delaying or stopping Alzheimer's disease.   view more (2006-05-02)

Researchers posit new ideas about human migration from Asia to Americas
Questions about human migration from Asia to the Americas have perplexed anthropologists for decades, but as scenarios about the peopling of the New World come and go, the big questions have remained.   view more (2007-10-26)

UCLA chemists' study of protein may provide insights into heart disease and cancer
UCLA chemists studying a protein associated with a rare genetic disease may also be gaining insights into cancer and heart disease.   view more (2006-08-11)

Novel mechanism for DNA replication discovered
Since the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pairings for replication.   view more (2005-09-30)

U of Alberta study discovers how proteins help repair DNA
A person's DNA is often damaged by a number of different chemical contaminants, and if not repaired properly, it can lead to the development of cancer and other diseases.   view more (2009-06-16)
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