Monoclonal B-cells Current Events | Monoclonal B-cells News
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Do patients at risk for B-cell malignancy need antiviral treatment?
Some studies have shown that a relationship of hepatitis C (HCV) infection with type II mixed cryoglobulinemia exists. However the precise mechanism remains unclear. view more (2009-04-15)
New treatment hope for prostate cancer
Scientists at Melbourne's Burnet Institute have developed a potential new treatment for patients with prostate cancer. An article, which described the invention, has recently been published in the prestigious international journal The Journal of Clinical Investigation. view more (2009-02-06)
Adding epratuzumab to standard therapy
Adding a second monoclonal antibody drug to chemotherapy looks promising for treatment of diffuse large B-cell lymphoma. view more (2008-05-16)
Lombardi research: Monoclonal antibodies primed to become potent immune weapons against cancer
New research suggests that monoclonal antibody therapy of cancer can be improved to be much more powerful than it is today, says a researcher at Georgetown University Medical Center's Lombardi Comprehensive Cancer Center in the March 21 issue of the Lancet. view more (2009-03-20)
Two targeted therapies likely better than one in patients with aggressive lymphoma
When combined with a cocktail of chemotherapy drugs, two monoclonal antibodies, instead of one, appear to offer superior results in patients with diffuse large B-cell lymphoma, according to Mayo Clinic researchers working with the North Central Cancer Treatment Group (NCCTG). view more (2009-05-15)
Adding radioimmunotherapy to chemo may help patients with lymphoma
Patients treated for follicular lymphoma, a slow-growing type of non-Hodgkin's lymphoma, may benefit from chemotherapy followed by radioimmunotherapy, according to a University of Pittsburgh Medical Center (UPMC) study presented at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago and published as Abstract 8005 in... view more... (2007-06-04)
A Landmark In The Understanding Of Thyroid Disease (pp 92, 126)
Authors of a research letter in this week's issue of THE LANCET report the discovery of the first human monoclonal thyroid stimulating autoantibody which could be an important step forward in understanding the underlying cause of a common thyroid disease. In Graves' disease (a disorder characterised by the production of autoantibodies),... view more... (2003-07-09)
Antibody retards growth and induces death in liver cancer cells
Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics. view more (2007-07-12)
UC Davis researchers report new molecule that targets leukemia and lymphoma cells
UC Davis Cancer Center researchers have developed a novel peptide that binds to the surface of leukemia and lymphoma cells with extremely high affinity, specificity and stability, and demonstrates remarkable promise as a tool to help image tumors and deliver anti-cancer drugs. view more (2006-06-13)
Monoclonal antibody reduces exacerbations in asthmatics
Patients with symptomatic moderate asthma who were treated with anti-tumor necrosis factor alpha, an anti-inflammatory monoclonal antibody, experienced significantly fewer disease exacerbations than individuals taking a placebo. view more (2006-10-02)
Infectious disease researchers develop basis for experimental melanoma treatment
While investigating a fungus known to cause an infection in people with AIDS, two grantees of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), unexpectedly discovered a potential strategy for treating metastatic melanoma, one of the deadliest forms of skin cancer. view more (2006-12-08)
Animal studies show promise for development of human SARS immunisation (pp 2102, 2122, 2139)
An article and research letter in this week's issue of THE LANCET provide evidence for the effectiveness of experimental SARS immunisation in animal studies. Although further research is required, these preliminary results show the potential for the development of human SARS immunisation. Alexander Bukreyev from the US National Institutes of... view more... (2004-06-23)
New study shows antibody-interleukin complexes stimulate immune responses
The findings could also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes. view more (2006-02-23)
Vaccine/antibody therapy effective, milder side effects in melanoma and ovarian cancer
One of the shortcomings of a therapy that uses millions of identical antibodies to boost the immune system's attack on cancer cells is that many patients whose tumors recede in response to the treatment also experience serious inflammatory problems, such as severe diarrhea and rashes. view more (2008-02-19)
Researchers from the University of Navarra analyze new kinds of cancer-fighting antibodies
Two researchers from the University Hospital and the Center for Applied Medical Research (CIMA) from the University of Navarra have published an article in Nature Cancer Reviews, one of the leading scientific journals in the area of cancer studies. view more (2007-03-07)
Treatment advances for lymphoma have reduced deaths by 70%
New treatment advances for patients with follicular lymphoma, previously considered an incurable cancer, have reduced deaths in the first four years by 70 percent. view more (2005-10-21)
Scientists identify lab-made proteins that neutralize multiple strains of seasonal and pandemic flu
Scientists have identified a small family of lab-made proteins that neutralize a broad range of influenza A viruses, including the H5N1 avian virus, the 1918 pandemic influenza virus and seasonal H1N1 flu viruses. view more (2009-02-23)
Jefferson and Delaware researchers combine tiny nanotubes and antibodies to detect cancer
By coating the surfaces of tiny carbon nanotubes with monoclonal antibodies, biochemists and engineers at Jefferson Medical College and the University of Delaware have teamed up to detect cancer cells in a tiny drop of water. view more (2005-11-17)
Scripps research scientists engineer new type of vaccination that provides instant immunity
The experiments, thus far performed only in mice, appear to overcome a major drawback of vaccinations - the lag time of days, or even weeks, that it normally takes for immunity to build against a pathogen. view more (2009-03-03)
First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
Origen Therapeutics today announced the first published scientific report of fully functional, human sequence monoclonal antibodies (mAbs) produced in chickens. The antibodies were expressed solely in the chicken oviduct and deposited into egg white in concentrations of 1-3 milligrams per egg. view more (2005-08-29)
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