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Researchers find brain cell transplants help repair neural damage
A Swiss research team has found that using an animal's own brain cells (autologous transplant) to replace degenerated neurons in select brain areas of donor primates with simulated but asymptomatic Parkinson's disease and previously in a motor cortex lesion model, provides a degree of brain protection and may be useful in repairing brain lesions... view more... (2009-10-29)

Telling axons where to go - and grow
In a recent study, Dr. Ingolf Bach and colleagues from the University of Massachusetts Medical School, Worcester and the University of Hamburg (Germany) describe a novel role for the ubiquitin/proteosome protein degradation pathway in the regulation of local actin dynamics in neurons.   view more (2005-10-03)

Cocaine-induced synaptic plasticity linked to persistent addictive behaviors
The persistent nature of addiction is its most devastating feature. Understanding the mechanism underlying this phenomenon is the key for designing efficient therapy. Two separate studies published by Cell Press is the August 14 issue of the journal Neuron identify specific cocaine-induced changes in dopamine (DA) neurons that play a pivotal role... view more... (2008-08-14)

Protein shown to play a key role in normal development of nervous system
A protein that enables nerve cells to communicate with each other plays a key role in controlling the developing nervous system.   view more (2008-10-08)

Researchers discover gene essencial to cerebellum formation
A study published this week in the scientific journal PNAS provides new information on the origin of different cells in the cerebellum, an important component of the central nervous system found in all vertebrates, including humans, and the part of the brain that controls movement.   view more (2007-03-07)

Early Promise For Stroke Patients Given
A preliminary study published in this week’s issue of THE LANCET suggests that the neurotransmitter precursor levodopa used in combination with physiotherapy could improve motor recovery for patients after stroke. Hemiplegia (paralysis to one side of the body) causes functional disability after stroke. Physiotherapy used to be the only way... view more... (2001-09-05)

Chemical cues turn embryonic stem cells into cerebellar neurons
In order to differentiate and specialize, stem cells require very specific environmental cues in a very specific order, and scientists have so far been unable to prod them to go through each of the necessary steps.   view more (2007-03-15)

"Booster rocket" malfunction implicated in Huntington's disease
CNRS and Inserm research scientists at the Institut Curie have shed new light on the function of huntingtin, the protein whose mutation underlies Huntington's disease. This neurodegenerative disease, like Alzheimer's or Parkinson's, is characterized by the abnormal death of certain neurons. The scientists have discovered that huntingtin, like a... view more... (2004-07-07)

Fibromyalgia pain caused by neuron mismatch, suggests study
The unexplained pain experienced by patients with fibromyalgia is the result of a mismatch between sensory and motor systems, new research suggests.   view more (2007-10-31)

Neurons grown from embryonic stem cells restore function in paralyzed rats
For the first time, researchers have enticed transplants of embryonic stem cell-derived motor neurons in the spinal cord to connect with muscles and partially restore function in paralyzed animals.   view more (2006-06-21)

Motor proteins may be vehicles for drug delivery
Specialized motor proteins that transport cargo within cells could be turned into nanoscale machines for drug delivery, according to bioengineers.   view more (2009-03-23)

Exercise may lead to improvement in patients with Parkinson's
A new study from researchers at the Keck School of Medicine of the University of Southern California (USC) shows that treadmill exercises may benefit patients with Parkinson's Disease and those with similar movement disorders.   view more (2007-05-16)

Streamlining brain signals for speed and efficacy
Life exists at the edge of chaos, where small changes can have striking and unanticipated effects, and major stimuli may go unheard.   view more (2008-10-23)

Study finds a high caloric diet may prevent the progression of amyotrophic lateral sclerosis
A recent study directed by the Mount Sinai School of Medicine suggests a ketogenic- high caloric diet may prevent the progression of Amyotrophic Lateral Sclerosis (ALS).   view more (2006-04-18)

New hope for Huntington's sufferers
A major breakthrough in the understanding and potential treatment of Huntington's disease has been made by scientists at the University of Leeds.   view more (2007-08-23)

Picking apart how neurons learn
Johns Hopkins researchers have used mouse mutants to define critical steps involved in learning basic motor skills. The study focuses on the behavior of two proteins and the specific steps they take to control a neuron's ability to learn by adapting to signals from other nerve cells.   view more (2006-03-30)

Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.   view more (2006-06-09)

Penn researchers engineer first system of human nerve-cell tissue
Researchers at the University of Pennsylvania School of Medicine have demonstrated that living human nerve cells can be engineered into a network that could one day be used for transplants to repair damaged to the nervous system. They report their findings in the February issue of the Journal of Neurosurgery.   view more (2008-02-27)

New brain cells listen before they talk
Newly created neurons in adults rely on signals from distant brain regions to regulate their maturation and survival before they can communicate with existing neighboring cells-a finding that has important implications for the use of adult neural stem cells to replace brain cells lost by trauma or neurodegeneration, Yale School of Medicine... view more... (2007-10-31)

A Novel Mechanism of Manganese-Induced Neurological Dysfunction Discovered
For decades, scientists have known that chronic exposure to high concentrations of the metal manganese can cause movement abnormalities resembling symptoms of Parkinson's disease, but apparently without the same neuron damage characteristic of Parkinson's patients.   view more (2006-08-29)
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