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Researchers discover molecular basis of a form of muscular dystrophy
A team of French and German researchers report in the May 2008 print issue of The FASEB Journal (http://www.fasebj.org) that people with limb-girdle muscular dystrophy are missing a protein called c-FLIP, which the body uses to prevent the loss of muscle tissue.   view more (2008-04-30)

Early cardiac screening necessary for muscular dystrophy patients
Early diagnosis and treatment of heart disease may lead to longer life in Duchenne and Becker muscular dystrophy patients.   view more (2005-10-31)

New therapeutic insight into duchenne muscular dystrophy
In the April 1st issue of Genes & Development, Dr. Bruce Spiegelman (Dana Farber Cancer Institute) and colleagues identify a key genetic component of and possible therapeutic target for Duchenne muscular dystrophy.   view more (2007-04-02)

Toxic molecule may cause most common type of muscular dystrophy
Doctors at the University of Virginia Health System have shown for the first time that getting rid of poisonous RNA (ribonucleic acid) in muscle cells can reverse myotonic dystrophy, the most common type of muscular dystrophy in adults.   view more (2006-08-25)

Stem cells - a cure for fatal muscular dystrophy
The diagnosis 'muscular dystrophy' is usually tantamount to a death sentence for those affected. One in three thousand male babies suffer from this incurable hereditary disease. The progress of the disease can only be slowed down through physiotherapy and medication. Scientists at Bonn University... view more (2002-07-04)

MRC Research Offers Hope of Treatment for People with Duchenne Muscular Dystrophy
A new approach which effectively patches over genetic defects offers hope of treatment to people with the terminal illness, Duchenne muscular dystrophy. This is the conclusion of research led by Dr Qi Long Lu and Professor Terence Partridge at the Medical Research Council's Clinical Sciences... view more (2003-07-04)

Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart
Heart disease is the leading cause of death in the United States and greatly affects the quality and length of life for individuals with specific forms of muscular dystrophy.   view more (2007-11-01)

UVA Reports Surprising Findings Related to Heart Protein, NKX2-5,
New research from the University of Virginia Health System shows that, in cases of Type 1 myotonic muscular dystrophy (DM1), a well known heart protein does several surprising things. DM1 is the most common form of muscular dystrophy in adults and affects approximately 40,000 adults and children in... view more (2007-12-18)

Genetics of muscular dystophy
Various forms of human muscular dystrophy result from mutations in genes encoding proteins of the nuclear envelope. A new paper in the February 15th issue of G&D reveals how.   view more (2006-02-15)

Switching genes to overdrive improves muscular dystrophy symptoms in mice
Scientists at Dana-Farber Cancer Institute have shown in a laboratory study that revving up a crucial set of muscle genes counteracts the damage caused by a form of muscular dystrophy.   view more (2007-04-02)

Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy
Muscle weakness and fiber deterioration seen in muscular dystrophy can be countered by a class of drugs currently under study for their effects against cancer.   view more (2006-09-18)

Research shows promise for potential new gene therapy strategy for muscle-wasting diseases
Investigators in The Research Institute at Nationwide Children's Hospital have identified the role of a protein that could potentially lead to new clinical treatments to combat musculoskeletal diseases, including Duchenne muscular dystrophy (DMD).   view more (2008-03-11)

New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
A new genetic test targeting the most common types of muscular dystrophy--those caused by mutations in the dystrophin gene--is far quicker with greater accuracy and sensitivity than existing tests. It can be used to confirm clinical diagnoses, to test female family members who may be carriers, and... view more (2007-06-28)

Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
A new gene therapy technique that has shown promise in skin disease and hemophilia might one day be useful for treating muscular dystrophy, according to a new study by researchers at Stanford University School of Medicine.   view more (2005-12-27)

New step toward treatment for Duchenne muscular dystrophy
Duchenne muscular dystrophy is a progressive weakening and degeneration of the muscles, caused by a mutation in a gene coding for a protein called dystrophin.   view more (2006-06-09)

Massive microRNA scan uncovers leads to treating muscle degeneration
Researchers have discovered the first microRNAs - tiny bits of code that regulate gene activity - linked to each of 10 major degenerative muscular disorders, opening doors to new treatments and a better biological understanding of these debilitating, poorly understood, often untreatable diseases.   view more (2007-10-18)

New approach to protect the hearts of patients with muscular dystrophy
A team of researchers has recently shown that the administration of sildenafil protects the heart in mice with Duchenne muscular dystrophy.   view more (2008-05-13)

Stem-cell transplantation improves muscles in MD animal model, UT Southwestern researchers report
Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy - and more importantly, functioning - muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy.   view more (2008-01-21)

Lending a helping arm
Cambridge engineers develop new system to help disabled peopleA group of engineers at the University of Cambridge has designed a new device to give a ‘helping arm’ to people with muscular weaknesses such as muscular dystrophy or motor neurone disease. The device, which can be attached... view more (2001-05-15)

Drug Fights Cystic Fibrosis
An experimental drug that has proven effective in treating muscular dystrophy also works for cystic fibrosis, according to researchers at the University of Alabama at Birmingham (UAB).   view more (2008-02-06)

Mouse study: New muscle-building agent beats all previous ones
The Johns Hopkins scientists who first created "mighty mice" have developed, with pharmaceutical company Wyeth and the biotechnology firm MetaMorphix, an agent that's more effective at increasing muscle mass in mice than a related potential treatment for muscular dystrophy now in clinical... view more (2005-12-09)

Researchers identify major source of muscle repair cells
In a surprising discovery with implications for treating muscular dystrophy, researchers at the University of Utah School of Medicine and other institutions have identified a major source of origin for two groups of adult cells that regulate muscle repair.   view more (2006-01-30)

Investigational drug tested for preventing muscle fiber death in muscular dystrophy
An investigational antiviral drug currently undergoing human trials in Europe for treating Hepatitis C infections may have potential to reduce muscle cell damage in Duchenne and other forms of muscular dystrophy (MD).   view more (2008-03-17)

'Mighty mice' made mightier
The Johns Hopkins scientist who first showed that the absence of the protein myostatin leads to oversized muscles in mice and men has now found a second protein, follistatin, whose overproduction in mice lacking myostatin doubles the muscle-building effect.   view more (2007-08-29)

New clinical trial results show how personalized medicine will alter treatment of genetic disorders
One of the nation's pre-eminent genetic researchers, Eric Hoffman, PhD, of Children's Research Institute at Children's National Medical Center, predicts that in relatively short order, medicine's next innovation--individualized molecular therapies--will have the unprecedented ability to treat... view more (2007-12-27)
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