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New imaging technique could promote early detection of multiple sclerosis
Researchers from Purdue University have studied and recorded how myelin degrades real-time in live mice using a new imaging technique. Myelin is the fatty sheath coating the axons, or nerve cells, that insulate and aid in efficient nerve fiber conduction. In diseases such as multiple sclerosis, the myelin sheath has been found to degrade. view more (2007-06-28)
Turning down gene expression promotes nerve cell maintenance
Anyone with a sweet tooth knows that too much of a good thing can lead to negative consequences. The same can be said about the signals that help maintain nerve cells, as demonstrated in a new study of myelin, a protein key to efficient neuronal transmission. view more (2009-02-02)
Claudin 11 stops the leaks in neuronal myelin sheaths
Devaux and Gow demonstrate how a tight junction protein called claudin 11 makes the neuronal myelin sheath a snug fit. view more (2008-12-01)
Pregnancy hormone increases nerve cells' insulation, restores damage
A hormone produced during pregnancy spontaneously increases myelin, which enhances signaling within the nervous system, and helps repair damage in the brain and spinal cord. view more (2007-02-21)
Cell therapy slows progression of an inherited neurological disease; Improves motor skills in mice
In an important discovery, scientists have demonstrated that the progression of a type of genetic brain disease is slowed and symptoms are improved in mice that received cell transplants. view more (2006-03-23)
Schizophrenia and bipolar disorder could have similar genetic causes (pp 758, 798)
Issue 6 September 2003 Embargoed 0001 h (London time) 5 September 2003. Authors of a study in this week's issue of THE LANCET provide strong evidence that schizophrenia and bipolar disorder have a similar genetic cause arising from reduced expression of genes responsible for myelin development of the central nervous system. Schizophrenia and... view more... (2003-09-03)
Multiple sclerosis research charges ahead with new mouse model of disease
A new study highlights the role of a charge-switching enzyme in nervous system deficits characteristic of multiple sclerosis and other related neurological illness. view more (2008-11-06)
Imaging study links key genetic risk for Alzheimer's disease to myelin breakdown
A new UCLA imaging study shows that age-related breakdown of myelin, the fatty insulation coating the brain's internal wiring, correlates strongly with the presence of a key genetic risk factor for Alzheimer disease. view more (2006-01-03)
Scientists push forward understanding of multiple sclerosis
New findings by a research team from the University of Edinburgh may help explain why diseases like multiple sclerosis (MS) which attack the myelin sheath - an insulator which protects the body's nervous system-cause such severe symptoms in MS patients. view more (2005-12-08)
Researchers discover gene crucial for nerve cell insulation
Researchers funded by the National Institutes of Health have discovered how a defect in a single master gene disrupts the process by which several genes interact to create myelin, a fatty coating that covers nerve cells and increases the speed and reliability of their electrical signals. view more (2007-04-17)
Combining multiple treatments improves multiple sclerosis therapy
Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS) in which white blood cells known as lymphocytes attack the myelin insulation on nerves in the spinal cord and brain. view more (2006-03-17)
Rutgers University Scientist's Research Reveals Critical Knowledge About the Nervous System
Uncover the neural communication links involved in myelination, the process of protecting a nerve's axon, and it may become possible to reverse the breakdown of the nervous system's electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system. view more (2007-11-07)
One size does not fit all
Statins, a commonly prescribed class of drugs used by millions worldwide to effectively lower blood cholesterol levels, may actually have a negative impact in Multiple Sclerosis (MS) patients treated with high daily dosages. view more (2009-05-26)
Myelin to Blame for Many Neuropsychiatric Disorders
What makes the human brain unique? Of the many explanations that can be offered, one that doesn't come readily to mind is - myelin. view more (2006-11-22)
Human ES cells progress slowly in myelin's direction
Scientists from the University of Wisconsin, USA, report in the journal Development the successful generation from human embryonic stem cells of a type of cell that can make myelin, a finding that opens up new possibilities for both basic and clinical research. view more (2009-04-09)
Researchers find molecule that inhibits regrowth of spinal nerve cells
A molecule that helps the body's motor nerve cells grow along proper paths during embryonic development also plays a major role in inhibiting spinal-cord neurons from regenerating after injury, researchers at UT Southwestern Medical Center have found. view more (2005-07-12)
Study gives more proof that intelligence is largely inherited
They say a picture tells a thousand stories, but can it also tell how smart you are? Actually, say UCLA researchers, it can. view more (2009-03-18)
Rethinking Alzheimer's disease and its treatment targets
The standard explanation for what causes Alzheimer's is known as the amyloid hypothesis, which posits that the disease results from of an accumulation of the peptide amyloid beta, the toxic protein fragments that deposit in the brain and become the sticky plaques that have defined Alzheimer's for more than 100 years. view more (2009-09-23)
Study finds gene related to brain development and function plays causal role in schizophrenia
According to a new study conducted by researchers at Mount Sinai School of Medicine, variations of a gene related to brain development and function-OLIG2-may play a causal role in the development of schizophrenia, a hereditary psychiatric disorder with no known biological cause. view more (2006-08-16)
New UW study offers strategy for treatment of fatal nervous system disorder
Working with mice, University of Wisconsin-Madison researchers have developed the basis for a therapeutic strategy that could provide hope for children afflicted with Krabbe's disease, a fatal nervous system disorder. view more (2005-12-13)
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