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Mouse model of osteoarthritis and more: Press release for PLoS Biology
Mouse model of osteoarthritis   view more (2004-10-12)

Light shed on vision and hearing disorders
The most common hereditary condition that affects both hearing and vision is Usher Syndrome (USH). In the next issue of The EMBO Journal, scientists at the Institut Pasteur report on studies that have established the first link between Myosin VIIa, Cadherin 23 and Harmonin b. These three proteins were previously known to be involved in the... view more... (2002-12-16)

Muscle atrophy through thick but not thin
During desperate times, such as fasting, or muscle wasting that afflicts cancer or AIDS patients, the body cannibalizes itself, atrophying and breaking down skeletal muscle proteins to liberate amino acids.   view more (2009-06-08)

Adult stem cells are touchy-feely, need environmental clues
A certain type of adult stem cell can turn into bone, muscle, neurons or other types of tissue depending on the "feel" of its physical environment.   view more (2006-08-25)

Dense tissue promotes aggressive cancers
New research may explain why breast cancer tends to be more aggressive in women with denser breast tissue. Breast cancer cells grown in dense, rigid surroundings step up their invasive activities, Vanderbilt-Ingram Cancer Center investigators report in the Sept. 9 issue of Current Biology.    view more (2008-08-25)

Inhibiting cell process may give cancer drug a boost
A molecule that interferes with the internal scaffolding that shapes the cell may kill cancer cells, retard the growth of tumors and give a boost to a common chemotherapy drug.   view more (2006-05-04)

Heart regenerates after infarction -- first trials with mice
Up until today scientists assumed that the adult heart is unable to regenerate. Now, researchers and cardiologists from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité - Universitätsmedizin Berlin (Germany) have been able to show that this dogma no longer holds true.   view more (2008-12-12)

UIC researchers make promising finding in severe lung disease
Researchers at the University of Illinois at Chicago have identified a novel function for an enzyme that plays a role in the tissue injury in acute respiratory distress syndrome, also known as ARDS.   view more (2008-06-30)

A twist in the tail - Leeds researchers show how sperm wriggle.
In a discovery with far-reaching potential for advances in infertility treatment, scientists at the University of Leeds have identified what makes sperm wriggle and swim. The answer lies in a protein called dynein. The scientists have taken the first photographs of individual molecules of dynein, also found in lungs, the nervous system and... view more... (2003-02-11)

Small mechanical forces have big impact on embryonic stem cells
Applying a small mechanical force to embryonic stem cells could be a new way of coaxing them into a specific direction of differentiation, researchers at the University of Illinois report. Applications for force-directed cell differentiation include therapeutic cloning and regenerative medicine.   view more (2009-10-19)

A stepwise retreat: how immune cells catch pathogens
To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria.   view more (2007-07-12)

Intestinal cells surprisingly active in pursuit of nutrition and defense
Every cell lining the small intestine bristles with thousands of tightly packed microvilli that project into the gut lumen, forming a brush border that absorbs nutrients and protects the body from intestinal bacteria.   view more (2009-06-29)
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