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Myostatin Current Events | Myostatin News
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'Mighty mice' made mightier
The Johns Hopkins scientist who first showed that the absence of the protein myostatin leads to oversized muscles in mice and men has now found a second protein, follistatin, whose overproduction in mice lacking myostatin doubles the muscle-building effect. view more (2007-08-29)
Mouse study: New muscle-building agent beats all previous ones
The Johns Hopkins scientists who first created "mighty mice" have developed, with pharmaceutical company Wyeth and the biotechnology firm MetaMorphix, an agent that's more effective at increasing muscle mass in mice than a related potential treatment for muscular dystrophy now in clinical trials. view more (2005-12-09)
A new kind of mutation could explain numerous phenotypic variations in various species
The authors describe the discovery of a novel class of mutations that disrupt the function of a gene and thereby cause a specific phenotype. The mutation created the appearance of an "illegitimate" microRNA (miRNA) recognition site in a gene that did not have it in its normal form. view more (2006-06-06)
Drugs to bulk up muscles may make injuries more likely
Block the action of a protein that normally regulates muscle mass, and watch your muscles grow. view more (2008-01-23)
Myostatin inhibitors may improve recovery of wartime limb injuries
Inhibiting a growth factor that keeps muscles from getting too big may optimize recovery of injured soldiers, researchers say. view more (2008-07-09)
Gene therapy accelerates healing of damaged skeletal muscle
University of Pittsburgh School of Medicine researchers have successfully used gene therapy to accelerate muscle regeneration in experimental animals with muscle damage, suggesting this technique may be a novel and effective approach for improving skeletal muscle healing, particularly for serious sports-related injuries. view more (2006-06-05)
MU logo News Bureau University of Missouri About the News Bureau Contact Us Home / News Releases / 2009 MU Researchers Discover Target that Could Ease Spinal Muscular Atrophy Symptoms
There is no cure for spinal muscular atrophy (SMA), a genetic disorder that causes the weakening of muscles and is the leading genetic cause of infant death, but University of Missouri researchers have discovered a new therapeutic target that improves deteriorating skeletal muscle tissue caused by SMA. The new therapy enhanced muscle strength,... view more... (2009-01-08)
Scientists Show Drug Can Counteract Muscular Dystrophy in Mice
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other institutions have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice that develop diseases comparable to two human forms of muscular dystrophy. view more (2006-10-05)
Long-term muscle improvements shown in gene therapy study in mice
Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows. view more (2008-03-11)
More muscle for the argument to give up smoking
Researchers at The University of Nottingham have got more bad news for smokers. Not only does it cause cancer, heart attacks and strokes but smokers will also lose more muscle mass in old age than a non-smoker. view more (2007-07-10)
Treatment to improve degenerating muscle gains strength
A study appearing in Science Translational Medicine puts scientists one step closer to clinical trials to test a gene delivery strategy to improve muscle mass and function in patients with certain degenerative muscle disorders. view more (2009-11-12)
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