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Small molecules mimic natural gene regulators
In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result when genes fail to turn on and off as they should.   view more (2009-06-04)

Carnegie Mellon, USDA report that Fe-TAML® catalysts degrade estrogenic compounds
Scientists from Carnegie Mellon University and the U.S. Department of Agriculture (USDA) have found that a rapid, environmentally friendly catalytic process involving Fe-TAML® activators and hydrogen peroxide breaks down two types of estrogenic compounds.   view more (2006-06-27)

Discovery offers new understanding of diabetes drug target
Scientists at the University of Leicester have published findings about a new advance in the study of major diabetes drug target.   view more (2008-09-26)

Future diabetes treatment may use resveratrol to target the brain
Resveratrol, a molecule found in red grapes, has been shown to improve diabetes when delivered orally to rodents. Until now, however, little has been known about how these beneficial changes are mediated in the body.   view more (2009-10-06)

The colour of your hair may leave you open to stereotypes and prejudice
Hair colour has been associated with stereotypes of females in western society and it appears that the stereotype of 'dumb blonde' is still alive and well. There is also some evidence that men rather than women have constructed the dumb blonde stereotype.   view more (1999-03-26)

Sirtris unveils promising, novel SIRT1 activators for treating diseases of aging
Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging, announced today that findings in the journal Nature demonstrate that Sirtris has developed novel drug candidates that offer a promising, new approach to treating diseases of aging,... view more... (2007-11-29)

Colon cancer shuts down receptor that could shut it down
Though a high-fiber diet has long been considered good for you and beneficial in staving off colon cancer, Medical College of Georgia researchers have discovered a reason why: roughage activates a receptor with cancer-killing potential.   view more (2009-04-14)

Natural born killers -- how the body's frontline immune cells decide which cells to destroy
The mechanism used by 'Natural Killer' immune cells in the human body to distinguish between diseased cells, which they are meant to destroy, and normal cells, which they are meant to leave alone, is revealed in new detail in research.   view more (2009-07-28)

Depression model leaves mice with molecular scar
In addition to triggering a depression-like social withdrawal syndrome, repeated defeat by dominant animals leaves a mouse with an enduring "molecular scar" in its brain that could help to explain why depression is so difficult to cure.   view more (2006-03-01)

Newly discovered small molecules
According to the study, these activators bind to specific sites on the neurotoxin protein, increasing protease activity and enhancing the toxin's effect.   view more (2006-03-15)

Opening a channel for salt retention
A research team has developed the first small molecule that can reversibly activate a key protein involved in balancing sodium levels, paving the way for drugs that can treat low blood pressure and related conditions.   view more (2008-04-28)

Mayo Clinic researchers find agents that speed up destruction of proteins linked to Alzheimer's
Taking a new approach to the treatment and prevention of Alzheimer's disease, a research team led by investigators at the Mayo Clinic campus in Florida has shown that druglike compounds can speed up destruction of the amyloid beta (A-beta) proteins that form plaque in the brains of patients with the disorder.   view more (2009-04-22)

Evolution: fish select for the survival of teh fittest
An important breakthrough has been made in determining the forces responsible for the evolution of populations in nature. By studying wild populations of grayling (a close relative of salmon), Mikko Koskinen and Craig Primmer at the University of Helsinki and Thrond Haugen at the University of Oslo found that natural selection, a force suggested... view more... (2002-10-30)

New insights into how the oncogenic protein c-Myc regulates cell growth
New findings by Swedish and German scientists on the regulation of cellular growth are published in the March issue of Nature Cell Biology.   view more (2005-02-20)

Newborn lambs' central heating system could aid fat busting in humans
The way newborn lambs regulate their temperature in the first few weeks of life using a special deposit of brown fat could give clues for tackling obesity in humans, according to Imperial College London scientists. Unlike normal white fat that stores surplus energy, brown fat generates heat in response to cold or excess caloric intake. While some... view more... (2004-04-14)

Masterminding muscle development
Dr. Lizi Wu (Dana Farber Cancer Institute) and colleagues report on a critical role for one of the three mammalian mastermind genes (Maml1) in myogenesis - assigning that first biological function to the mammalian MAML Notch co-activators.   view more (2006-02-28)

University of Helsinki to coordinate two large EU research projects
The European Union has granted nearly 25 MEUR to two large-scale interdisciplinary research projects coordinated by the University of Helsinki. The project leaders are professor Raimo Tuominen from the UH's Faculty of Pharmacy and Academy professor Kari Alitalo from UH's Molecular and Cancer Biology Laboratory. Both projects are part of the... view more... (2004-08-24)

Finland and China sign new funding agreement
Research cooperation since the early 1980s The Academy of Finland and the National Natural Science Foundation of China have signed an agreement concerning the funding of joint projects among centres of excellence in research. The closing date for the current round of applications is 11 January 2002. Funding is available for joint projects in two... view more... (2001-12-19)

Polluted ground water poured into a model
Dutch researcher Phil Ham has developed mathematical models to calculate the natural degradation capacity of polluted groundwater.    view more (2006-04-19)

Liver fibrosis will be treated by a potential target
The outcome of hepatitis is either self recovery or its development into liver fibrosis or, further, liver cirrhosis. Liver fibrosis is the early pathological process of cirrhosis, which is considered a reversible, wound-healing response. Since no ideal drug is available for its therapy, liver fibrosis is currently considered to be a major... view more... (2007-10-17)
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