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The Lancet Oncology (TLO) For immediate release
IS PREVENTION REALLY BETTER THAN CURE? Billions of dollars are currently being spent on the search for effective drugs that will stop disease before it happens. Advances in genetic testing are providing more opportunities to find out which diseases people are likely to be at risk of developing-but this knowledge has put huge pressure on the... view more... (2002-10-30)
'Erectile dysfunction' drugs heighten natural anti-cancer activity
Sildenafil and other "impotence drugs" that boost the production of a gassy chemical messenger to dilate blood vessels and produce an erection now also show promise in unmasking cancer cells so that the immune system can recognize and attack them, say scientists at the Johns Hopkins Kimmel Cancer Center. view more (2006-12-08)
Neuroblastoma expert reviews progress and challenges in fighting difficult pediatric cancer
Childhood cancers are fortunately rare, but among them, neuroblastoma is a special case, accounting for 7 percent of all childhood cancers, but 15 percent of childhood cancer deaths. view more (2007-06-25)
Media Registration: Europe`s largest breast cancer conference to be held in Barcelona
3rd European Breast Cancer Conference (EBCC-3) Palau de Congressos de Catalunya, Barcelona, Spain 19-23 March 2002 ABOUT EBCC-3"¦ * More than 3000 clinicians, scientists and patient advocates will attend. * Presentations will review new developments in molecular biology, epidemiology, prevention, diagnosis, treatment, psycho-social... view more... (2001-12-04)
Novel 4-drug combination proves safe for lung cancer treatment
The four drug-combination of carboplatin and paclitaxel, with the targeted therapies bevacizumab (Avastin) and cetuximab (Erbitux), is safe and may improve survival for patients with advanced lung cancer, according to a cooperative group study led by The University of Texas M. D. Anderson Cancer Center. view more (2008-11-13)
Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors. view more (2006-08-15)
Cancer Research UK supports additional TroVax phase II trial in colorectal cancer
Oxford BioMedica announced today that Cancer Research UK (CRUK) has agreed to conduct and sponsor an open label Phase II trial with Oxford BioMedica's leading cancer immunotherapy product, TroVax®, in colorectal cancer patients who have liver metastases. The decision by CRUK follows extensive review of the successful Phase I/II data of TroVax... view more... (2003-08-28)
Estrogen-progestin menopausal hormone therapy and risk of lobular and tubular breast cancer
Estrogen-progestin menopausal hormone therapy is associated with a more than two-fold higher relative risk of developing lobular cancer or tubular cancer than of developing ductal cancer. view more (2006-02-17)
Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of the Opioid Growth Factor (OGF, [Met5]-enkephalin), a clinically important antitumor agent, is dependent on nucleocytoplasmic translocation and reliant on the integrity of nuclear localization signals in the OGF receptor... view more... (2009-04-23)
Vandetanib shows clinical benefit when combined with docetaxel for lung cancer
When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer. view more (2009-06-01)
Taking aim at mysterious DNA structures in the battle against cancer
Designers of anti-cancer drugs are aiming their arrows at mysterious chunks of the genetic material DNA that may play a key role in preventing the growth and spread of cancer cells, according to an article in the current issue of Chemical & Engineering News, ACS' weekly newsmagazine. view more (2009-11-05)
Does public information about cancer screening do more harm than good?
Researchers at Imperial Cancer Research Fund have overturned claims that information provided to the public as part of a cancer screening programme increases people's anxiety about the disease and worries them unnecessarily. Their work is published today in the British Medical Journal*. view more (1999-10-13)
High rates of skin cancer among airline pilots
Rates and types of cancer were assessed in 458 pilots, 265 of whom flew the national Icelandic airline across European and transAtlantic routes. These were then compared with the rates of cancer expected to develop in the population as a whole, gathered from data supplied by the national cancer registry, according to age. view more (2000-02-14)
Prophylactic cranial irradiation in small cell lung cancer significantly increases survival
Prophylactic cranial irradiation after chemotherapy significantly reduces the risk of brain metastasis and doubles one-year survival in small-cell lung cancer (SCLC). view more (2007-08-17)
Improving understanding of cell behaviour in breast cancer
The invasion and spread of cancer cells to other parts of the body, known as metastasis, is a principal cause of death in patients diagnosed with breast cancer. view more (2008-07-16)
PREOPERATIVE RADIOTHERAPY IMPROVES OUTCOME IN RECTAL CANCER (PP 1285, 1291)
Preoperative radiotherapy reduces risk of local recurrence and death from rectal cancer, conclude authors of a systematic overview published in this week's issue of The Lancet. There are different opinions about when it is best to give radiotherapy for rectal cancer. In Scandinavia, the Netherlands, and some other European countries, radiotherapy... view more... (2001-10-17)
The National Radiological Protection Board advises holiday makers against overexposure to high sunlight
The incidence of skin cancer in the UK has significantly increased in recent years. There are now over 40,000 new cases and nearly 2,000 deaths from skin cancer in the UK each year. Much of this increase has been attributed to overexposure to sunlight not only when abroad but also sunbathing at home. In one recent study in Scotland, a third of... view more... (2003-05-27)
Scripps Florida scientists find novel use for old compound in cancer treatment
The compound, α-difluoromethylornithine or DFMO, targets the activity of a specific enzyme and, even in very limited doses, is effective in protecting against the malignancy in animal models. view more (2009-01-16)
Bowel cancer sufferers at risk of developing other unrelated cancers faster than expected
Bowel cancer sufferers are at increased risk of developing other completely different cancers at a higher rate than would be expected, finds a study in Gut. And this excludes recurrence of, or spread (metastasis) from, the original tumour. view more (2002-04-09)
Popular Magazines Don't Inform Men About Prostate and Colon Cancer Screening
Decisions about screening for prostate and colon cancer require patients to have accurate, balanced information. Unfortunately, men are not getting this information from popular men's magazines. When articles are available, they often do not provide the information necessary for the reader to make an informed decision about screening. view more (2004-09-08)
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