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Could skin cells become brain cells? (p 172)
Results of an experimental study in this week's issue of THE LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders such as Parkinson's disease. Ethical and practical considerations limit the... view more (2004-07-07)

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)

Stem cells as cancer therapy
It is widely hoped that neural stem cells will eventually be useful for replacing nerves damaged by degenerative diseases like Alzheimer disease and multiple sclerosis. But there may also be another use for such stem cells-delivering anti-cancer drugs to cancer cells.   view more (2006-12-26)

Post brain injury: New nerve cells originate from neural stem cells
Most cells in the human brain are not nerve cells, but supporting cells (glial cells). They serve as a framework for nerve cells and play an important role in the wound reaction that occurs with injuries to the brain.   view more (2008-03-12)

Neural stem cells reduce Parkinson's symptoms in monkeys
Primates with severe Parkinson's disease were able to walk, move, and eat better, and had diminished tremors after being injected with human neural stem cells.   view more (2007-06-13)

Researchers link early stem cell mutation to autism
In a breakthrough scientific study published today in the Proceedings of the National Academy of Sciences, scientists at the Burnham Institute for Medical Research have shown that neural stem cell development may be linked to Autism.   view more (2008-07-01)

Neural stem cells derived from human embryonic stem cells carry abnormal gene expression
Neural stem cells grown from one of the federally approved human embryonic stem cell lines proved to be inferior to neural stem cells derived from fetal tissue donated for research, a UCLA study has found.   view more (2006-08-07)

Researchers reveal repressor protein blocks neural stem cell development
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons.   view more (2007-10-11)

Building brains: Mammalian-like neurogenesis in fruit flies
A new way of generating brain cells has been uncovered in Drosophila. The findings, published this week in the online open access journal Neural Development, reveal that this novel mode of neurogenesis is very similar to that seen in mammalian brains, suggesting that key aspects of neural... view more (2008-02-19)

Carnegie Mellon researchers to develop new drug delivery system
Carnegie Mellon University's Stefan F. Zappe is using adult neural stem cells to develop a new stem cell-based drug delivery therapy that may ultimately help treat a variety of inherited genetic disorders like Hunter syndrome.   view more (2007-11-05)

Making a face: A new and earlier marker of neural crest development
The fate of cells that go on to form the face, skull and nerve centers of the head and neck in vertebrates is determined much earlier in development than previously thought, and is independent of interaction with other forming tissues.   view more (2006-07-12)

Chemotherapy can be more toxic to brain cells than to cancer cells and may cause brain damage
Drugs used to treat cancer may damage normal, healthy brain cells more than the cancer cells they are meant to target.   view more (2006-11-30)

The development of stem cells -- not only which and where but also WHEN
Yet another stride has been taken on the road to knowledge about the development of the nervous system. For the first time factors have been uncovered that decide when a cell is to develop into another cell. During the last ten years much progress has been made in finding out what determines how... view more (2003-03-20)

Adult human neural stem cell therapy successful in treating spinal cord injury
Researchers at the UC Irvine Reeve-Irvine Research Center have used adult human neural stem cells to successfully regenerate damaged spinal cord tissue and improve mobility in mice.   view more (2005-09-20)

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells
Having recently identified the molecular signature of these epidermal neural crest stem cells in the mouse, their research resolves conflicting scientific opinions by showing that these cells are distinctly different from other types of skin-resident stem cells/progenitors. Their work provides a... view more (2006-12-12)

Possible birthplace of malignant brain tumors identified
Researchers have found that abnormal stimulation of a cellular trigger that normally regulates replenishment of brain cells in adults causes invasive tumor-like growths in mice.   view more (2006-07-20)

Neural Stem Cells Are Long-Lived
New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year - most of the life span of a mouse - and give rise to multiple types of neural cells, not just neurons.   view more (2005-10-06)

Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments
UC Irvine School of Medicine researchers have discovered how new neurons born from endogenous neural stem cells are sent to regions of the brain where they can replace old and dying cells, a finding that suggests how stem cell therapies can be specifically targeted to brain regions affected by... view more (2005-06-24)

Marrow-derived stem cells deliver new cytokine to kill brain tumor cells, offer protection
Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return.   view more (2006-03-01)

MIT: Stem-cell therapies for brain more complicated than thought
An MIT research team's latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought.   view more (2007-11-28)

Neural stem cell gene plays crucial role in eye development
Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place.   view more (2006-05-16)

Researchers identify genes that allow brain cancer-causing stem cells to resist treatment
While great interest has followed the discovery of neural stem cells and their potential for someday treating diseases and injuries of the brain and spinal cord, recent research identified "cancer stem cells," a small population of cells that appear to be the source of cells comprising a... view more (2006-12-18)

'Gateway' gene discovered for brain cancer
Researchers have discovered that the same genetic regulator that triggers growth of stem cells during brain development also plays a central role in the development of the lethal brain cancer malignant glioma.   view more (2007-02-15)

Insight into neural stem cells has implications for designing therapies
Scientists have discovered that adult neural stem cells, which exist in the brain throughout life, are not a single, homogeneous group.   view more (2007-07-09)

Tapping into spinal cures
Stem cells which give rise to vertebrae, muscle and the spinal cord have been identified for the first time by Dr. Valerie Wilson (University of Edinburgh). "These axial stem cells could be used in the future to help replace damaged tissues after back injuries", says Dr. Wilson who will... view more (2004-03-26)

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