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Could skin cells become brain cells? (p 172)
Results of an experimental study in this week's issue of THE LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders such as Parkinson's disease. Ethical and practical considerations limit the availability of neural stem cells derived from... view more... (2004-07-07)
When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions. view more (2007-08-27)
Stem cells as cancer therapy
It is widely hoped that neural stem cells will eventually be useful for replacing nerves damaged by degenerative diseases like Alzheimer disease and multiple sclerosis. But there may also be another use for such stem cells-delivering anti-cancer drugs to cancer cells. view more (2006-12-26)
Post brain injury: New nerve cells originate from neural stem cells
Most cells in the human brain are not nerve cells, but supporting cells (glial cells). They serve as a framework for nerve cells and play an important role in the wound reaction that occurs with injuries to the brain. view more (2008-03-12)
Neural stem cells reduce Parkinson's symptoms in monkeys
Primates with severe Parkinson's disease were able to walk, move, and eat better, and had diminished tremors after being injected with human neural stem cells. view more (2007-06-13)
An inexhaustible source of neural cells
Research scientists in Bonn have succeeded in deriving so-called brain stem cells from human embryonic stem cells. These can not only be conserved almost indefinitely in culture, but can also serve as an inexhaustible source of diverse types of neural cell. view more (2009-02-17)
Researchers link early stem cell mutation to autism
In a breakthrough scientific study published today in the Proceedings of the National Academy of Sciences, scientists at the Burnham Institute for Medical Research have shown that neural stem cell development may be linked to Autism. view more (2008-07-01)
Neural stem cells derived from human embryonic stem cells carry abnormal gene expression
Neural stem cells grown from one of the federally approved human embryonic stem cell lines proved to be inferior to neural stem cells derived from fetal tissue donated for research, a UCLA study has found. view more (2006-08-07)
Researchers reveal repressor protein blocks neural stem cell development
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons. view more (2007-10-11)
Neural stem cells offer potential treatment for Alzheimer's disease
UC Irvine scientists have shown for the first time that neural stem cells can rescue memory in mice with advanced Alzheimer's disease, raising hopes of a potential treatment for the leading cause of elderly dementia that afflicts 5.3 million people in the U.S. view more (2009-07-21)
Neural stem cell differentiation factor discovered
Neural stem cells represent the cellular backup of our brain. These cells are capable of self-renewal to form new stem cells or differentiate into neurons, astrocytes or oligodendrocytes. view more (2009-06-30)
Building brains: Mammalian-like neurogenesis in fruit flies
A new way of generating brain cells has been uncovered in Drosophila. The findings, published this week in the online open access journal Neural Development, reveal that this novel mode of neurogenesis is very similar to that seen in mammalian brains, suggesting that key aspects of neural development could be shared by insects and mammals. view more (2008-02-19)
Carnegie Mellon researchers to develop new drug delivery system
Carnegie Mellon University's Stefan F. Zappe is using adult neural stem cells to develop a new stem cell-based drug delivery therapy that may ultimately help treat a variety of inherited genetic disorders like Hunter syndrome. view more (2007-11-05)
Tumor suppressor gene in flies may provide insights for human brain tumors
In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor. view more (2009-06-23)
Making a face: A new and earlier marker of neural crest development
The fate of cells that go on to form the face, skull and nerve centers of the head and neck in vertebrates is determined much earlier in development than previously thought, and is independent of interaction with other forming tissues. view more (2006-07-12)
Chemotherapy can be more toxic to brain cells than to cancer cells and may cause brain damage
Drugs used to treat cancer may damage normal, healthy brain cells more than the cancer cells they are meant to target. view more (2006-11-30)
The development of stem cells -- not only which and where but also WHEN
Yet another stride has been taken on the road to knowledge about the development of the nervous system. For the first time factors have been uncovered that decide when a cell is to develop into another cell. During the last ten years much progress has been made in finding out what determines how various types of nerve cells develop from a stem... view more... (2003-03-20)
Adult human neural stem cell therapy successful in treating spinal cord injury
Researchers at the UC Irvine Reeve-Irvine Research Center have used adult human neural stem cells to successfully regenerate damaged spinal cord tissue and improve mobility in mice. view more (2005-09-20)
Hebrew University scientists succeed through stem cell therapy in reversing brain birth defects
Scientists at the Hebrew University of Jerusalem have succeeded in reversing brain birth defects in animal models, using stem cells to replace defective brain cells. view more (2008-12-30)
Stem cells found in adult hair follicles may provide alternative to embryonic stem cells
Having recently identified the molecular signature of these epidermal neural crest stem cells in the mouse, their research resolves conflicting scientific opinions by showing that these cells are distinctly different from other types of skin-resident stem cells/progenitors. Their work provides a valuable resource for future mouse neural crest stem... view more... (2006-12-12)
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