Neural Tube Current Events | Neural Tube News
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New insights into neural tube defects
Environmental and genetic factors lead to neural tube defects in 1 in every 1,000 births and cause 1 in 20 of every spontaneous abortion. One cause of these defects is the failure of cells within the neural tube to migrate to the middle of the developing neural tube. view more (2006-01-12)
European folic acid policies are not effective enough
The prevalence of neural tube defects in Europe has not declined substantially in the past decade, despite national policies of folic acid supplementation in half the countries, finds a study in this week's BMJ. view more (2005-03-09)
Food Supplementation With Folic Acid Could Substantially Reduce Neural-Tube Defects (p 2047)
A public-health initiative to enrich cereal grain foods in Canada with folic acid has halved the prevalence of neural-tube defects among both unborn and newborn children, report authors of a research letter in this week's issue of THE LANCET. Folic acid tablet supplementation around the time of conception is known to dramatically reduce the risk... view more... (2002-12-18)
Can Genetic Research Improve Public Health?
Genetic studies have an important part to play in the health of the general public, according to new research from Bristol University published today in the International Journal of Epidemiology. Although reports of claims that a particular gene has been found for a particular disease are often inaccurate, genetic studies can be used to identify... view more... (2003-04-11)
Concerns raised over policy to add folic acid to flour
A UK Department of Health committee has now recommended universal fortification of flour with folic acid to reduce the level of neural tube defects. Yet researchers in this week's BMJ warn that we need to be cautious before introducing such a policy. Although the benefits of supplementation are clear, the possible harms of such a policy are not,... view more... (2001-11-20)
A safe folic acid boost from flour
Public consumption of folic acid from fortified flour at current mandated US levels (100micro-gram/day) and at double this amount is probably safe, at average intakes, according to an article published today in the open access journal BMC Public Health. view more (2007-03-22)
Fortifying food with folic acid benefits babies
Adding folic acid to food can dramatically reduce the incidence of spina bifida and other birth defects. A study, published today in BMC Pregnancy and Childbirth, shows that the proportion of babies born with neural tube defects in the province of Newfoundland and Labrador dropped by 78% after the Canadian Government directed that folic acid must... view more... (2004-09-23)
Are certain congenital birth defects and heart disease linked?
The study implicates homocysteine, a chemical by-product of human metabolism. Homocysteine is particularly important for cell growth and is regulated by enzymes, the activities of which are partly genetically determined, and partly affected by diet, including the levels of vitamins B6, B12, and folic acid in the blood. view more (1999-11-15)
Multivitamins with 0.4 - 0.8 mg of folic acid are best in birth defect prevention
Periconceptional use of folic acid supplements is effective for the primary prevention of neural-tube defects and is recommended by reproductive health researchers. Recent research in this area, however, centres on two main debated questions. The first one is whether the use of folic acid alone or folic acid-containing multivitamins is better. The... view more... (2004-05-27)
Some neural tube defects in mice linked to enzyme deficiency
Women of childbearing age can reduce the risk of having a child born with a neural tube defect such as spina bifida by eating enough folate or folic acid. However, folate prevents only about 70 percent of these defects. view more (2009-05-26)
Adding folic acid to flour significantly reduces congenital malformations
Dr. Philippe De Wals of Université Laval's Department of Social and Preventive Medicine today publishes a study clearly indicating that the addition of folic acid to flours has led to a 46% drop in the incidence of congenital neural tube deformation (mainly anencephaly and spina bifida) in Canada. view more (2007-07-13)
Immigrant women may be at higher risk of having a baby with a birth defect
Immigrant women are less likely to use folic acid supplements before pregnancy to prevent spina bifida, particularly those who recently immigrated to the country, according to a new study led by a St. Michael's Hospital physician in collaboration with Statistics Canada, Health Canada and the University of Toronto. view more (2009-04-17)
Acute pancreatitis and cholangitis: a complication caused by a migrated gastrostomy tube
Percutaneous endoscopic gastrostomy (PEG) is generally considered to be safe with a low rate of serious complications. However, dislocation of a gastrostomy tube can lead to serious complications. view more (2007-10-25)
Food Fortification With Vitamin B12 In Addition To Folic Acid Could Reduce Risk Of Cardiovascular Disease (p 227)
Authors of a research letter in this week's issue of THE LANCET conclude that vitamin B12 in addition to folic acid should be used to fortify food to lower concentrations of the blood protein homocysteine, thereby potentially reducing the risk of cardiovascular disease. Mandatory fortification of grain foods with folic acid has been in place in... view more... (2002-01-17)
Study Suggests Link Between Down's Syndrome And Neural-tube Defects (pp 1316, 1331)
Authors of a study in this week's issue of THE LANCET highlight how infants born within families who have a high risk of neural-tube defects (NTD) could also be at an increased risk of Down's syndrome-and vice versa, suggesting an association between Down's syndrome and NTD. NTD are birth defects of the brain or spinal cord caused by abnormal... view more... (2003-04-16)
BID TO DETECT BREATHING PROBLEMS IN THE NEWBORN
Professor Neil McIntosh and Dr Andrew Lyall of Child Life and Health, and Professor Alan Murray of Electronics & Electrical Engineering have been awarded a Chief Scientist Office (Scottish Office Department of Health) grant of £16,139 for work using an artificial neural network to alert hospital staff to air tube blockages, or air or gas... view more... (1999-01-22)
Folic Acid Supplements Not Linked To Multiple Births (p 380)
Results of a Chinese population-based study in this week's issue of THE LANCET provide strong evidence that women who take folic acid supplements during pregnancy do not have an increased likelihood of having a multiple birth. Folic acid supplements are recommended for women of childbearing age to prevent neural tube defects-such as spina bifida... view more... (2003-01-29)
New molecular insight into vertebrate brain development
In the December 1st issue of G&D, Dr. Fred H. Gage (The Salk Institute for Biological Studies) and colleagues reveal a role for the Hippo signaling pathway in the regulation of vertebrate neural development, identifying new factors - and potential therapeutic targets - that may be involved in congenital brain size disorders and neurological... view more... (2008-11-18)
Low levels of vitamin B12 may increase risk for neural tube defects
Children born to women who have low blood levels of vitamin B12 shortly before and after conception may have an increased risk of a neural tube defect, according to an analysis by researchers at the National Institutes of Health, Trinity College Dublin, and the Health Research Board of Ireland. view more (2009-03-02)
Prenatal vitamins may reduce risk of brain tumors in children
Women who take multivitamins early in pregnancy may reduce the risk that their child will develop some types of brain tumors. view more (2006-09-21)
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