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Molecular basis for neurodegeneration in Ataxia telangiectasia
An upcoming paper from Dr. David Wassarman (University of Wisconsin School of Medicine and Public Health) in the May 1 issue of G&D lends new insight into the pathogenesis of neurodegeneration in Ataxia telangiectasia.   view more (2008-04-15)

Rhode Island Hospital study finds link between obesity, type 2 diabetes and neurodegeneration
New research from Rhode Island Hospital found that obesity and Type 2 Diabetes Mellitus (T2DM) can contribute to mild neurodegeneration with features common with Alzheimer's disease (AD) - the first study to show that obesity can cause neurodegeneration.   view more (2008-09-05)

Cell-surface sugar defects may trigger nerve damage in multiple sclerosis patients
Defects on cell-surface sugars may promote the short-term inflammation and long-term neurodegeneration that occurs in the central nervous system of multiple sclerosis patients, according to University of California, Irvine researchers.   view more (2007-09-21)

New study provides further evidence that apple juice can delay onset of Alzheimer's disease
A growing body of evidence demonstrates that we can take steps to delay age-related cognitive decline, including in some cases that which accompanies Alzheimer's disease, according to a study published in the January 2009 issue of the Journal of Alzheimer's Disease.   view more (2009-01-23)

New study provides further evidence that apple juice can delay onset of Alzheimer's disease
A growing body of evidence demonstrates that we can take steps to delay age-related cognitive decline, including in some cases that which accompanies Alzheimer's disease, according to a study published in the January 2009 issue of the Journal of Alzheimer's Disease.   view more (2009-01-23)

Untangling a pathology of Alzheimer's
Researchers have uncovered what appears to be a natural protective mechanism against a central cause of neuronal death in Alzheimer's and similar neurodegenerative diseases.   view more (2006-09-07)

Study suggests new treatments for Huntington's disease
Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington's disease causes neurodegeneration.   view more (2008-01-10)

Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease.   view more (2007-11-14)

Prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases
Study shows prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases such as atherosclerosis, diabetes and neurodegeneration.   view more (2009-09-14)

3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually.   view more (2008-10-29)

Insulin receptor stops progression of Alzheimer's disease
Stimulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages.   view more (2006-09-22)

Anesthesia is found to induce hyperphosphorylation of tau at sites related to Alzheimer's disease
Scientists from The New York State Office of Mental Retardation and Developmental Disabilities' (OMRDD) New York State Institute for Basic Research in Developmental Disabilities (IBR) report today in the March 2009 issue of the Journal of Alzheimer's Disease that anesthesia induces phosphorylation of tau.   view more (2009-03-10)

Study ties 'new' cell-death mechanism to developmental and degenerative brain disorders
An international research team has provided the first conclusive evidence that neurodevelopmental disorders such as mental retardation and neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and ataxias can be caused, at least in part, by specific gene defects that interfere with the electrical impulses of rapid-firing... view more... (2006-02-28)

Age-related memory improvement linked with consumption of apple products
New research from the University of Massachusetts Lowell suggests that consuming apple juice may protect against cell damage that contributes to age-related memory loss, even in test animals that were not prone to developing Alzheimer's disease and other dementias.   view more (2006-01-25)

Transcription factor protein's role in cell death, neurodegeneration and schizophrenia
Researchers at the University of Pennsylvania School of Medicine discovered that a protein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein -— typically active in the nucleus — could play a role in cell death and mitochondria-related diseases such as neurodegeneration and... view more... (2006-06-08)

New mechanism found for neurodegenerative effects of amphetamines in mice
University of Toronto researchers have discovered a new mechanism for the neurodegenerative effects of amphetamines.   view more (2006-04-06)

RNA Toxicity Contributes to Neurodegenerative Disease, University of Pennsylvania Scientists Say
Expanding on prior research performed at the University of Pennsylvania, Penn biologists have determined that faulty RNA, the blueprint that creates mutated, toxic proteins, contributes to a family of neurodegenerative disorders in humans.   view more (2008-05-22)

Disease-causing protein protects against nerve damage in Parkinson's disease
Researchers at UT Southwestern Medical Center have discovered that a protein associated with causing neurodegenerative conditions may, when appearing in normal amounts, actually protect against neurodegeneration.   view more (2005-11-04)

Study implicates potassium channel mutations in neurodegeneration and mental retardation
For the first time, researchers have linked mutations in a gene that regulates how potassium enters cells to a neurodegenerative disease and to another disorder that causes mental retardation and coordination problems.   view more (2006-02-27)

Scientists discover possible link between oxidative stress and non-hereditary degenerative disease
The irreversible neurological degeneration associated with Parkinson's and Alzheimer's diseases may be the consequence of oxidative stress-the imbalance of antioxidants and pro-oxidants in cells.   view more (2006-04-28)
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