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Salk and Stanford teams join forces to reveal two paths of neurodegeneration
Wiring the developing brain is like creating a topiary garden. Shrubs don't automatically assume the shape of ornamental elephants, and neither do immature nerve cells immediately recognize the "right" target cell. Abundant foliage, either vegetal or neuronal, must first sprout and then... view more (2006-06-15)

Scientists close in on genes responsible for Parkinson's disease
Scientists have identified 570 genes that act abnormally during the development of Parkinson's Disease, a finding which could help doctors predict the likelihood of it developing, and provide targets for new treatments.   view more (2005-12-20)

More brain research suggests
Queensland Brain Institute (QBI) scientists have found another important clue to why nerve cells die in neurodegenerative diseases, based on studies of the developing brain.   view more (2008-02-07)

Genetics of ALS progression
An upcoming paper from Drs. Hidenori Ichijo and Hideki Nishitoh (The University of Tokyo) and colleagues lends new and valuable insight into the genetics of ALS.   view more (2008-06-02)

The UAB heads a European research project on proteases and pathological processes
A research group of the UAB Institute of Biotechnology and Biomedicine and the UAB Department of Biochemistry and Molecular Biology, directed by Francesc Xavier Avilés, is the coordinator of a European project aimed at studying proteases with fluorescent molecules that allow their monitoring... view more (2007-07-18)

Grape expectations for healthier wine
A new technique that uses ozone to preserve grapes could help prevent allergies and boost healthy compounds at the same time, reports Jennifer Rohn in Chemistry & Industry, the magazine of the SCI.   view more (2007-02-12)

Prions link cholesterol to neurodegeneration
Prion infection of neurons increases the free cholesterol content in cell membranes. A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for... view more (2008-02-12)

Receptor critical in neurodegeneration reduces Alzheimer's plaque
Increasing the level of a protein that plays a key role in traumatic spinal cord injuries and multiple sclerosis reduces the concentration of disease-causing plaque in Alzheimer's disease.   view more (2006-02-03)

'Rotten eggs' in the blood
Hydrogen sulphide (H2S) is a gas most commonly associated with the smell of stink bombs, sewage and rotten eggs, but a team of researchers from the Peninsula Medical School in the South West of England and King's College London have now identified a role for this gas in regulating blood pressure,... view more (2008-04-30)

A probable cause for Parkinson's?
Parkinson's, Alzheimer's, Lou Gehrig's disease and other brain disorders are among a growing list of maladies attributed to oxidative stress, the cell damage caused during metabolism when the oxygen in the body assumes ever more chemically reactive forms.   view more (2006-06-28)

Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
Nematode worms treated with lithium show a 46 percent increase in lifespan, raising the tantalizing question of whether humans taking the mood affecting drug are also taking an anti-aging medication.   view more (2007-10-31)

Discoveries should aid research into cause of ALS
Two teams of researchers at Northwestern University have found a novel pathological hallmark of the neurodegenerative disease amyotrophic lateral sclerosis (ALS) at the molecular level.   view more (2006-04-26)

Scientists on track for early diagnosis of neurological diseases
Possible treatments for fatal neurodegenerative diseases such as CJD, Alzheimer's, Parkinson's could result from University of Edinburgh research to find out how specific proteins cause deterioration in brain function. The scientists have discovered for the first time that protein 14-3-3 plays a... view more (2003-07-01)

Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.   view more (2006-06-09)

Natural compound and exercise boost memory in mice
A natural compound found in blueberries, tea, grapes, and cocoa enhances memory in mice, according to newly published research. This effect increased further when mice also exercised regularly.   view more (2007-05-30)

THE BIOCHEMIST - June 2002 Issue; Theme: A morbid fascination - Deadly serious
Introduction - The answer to a shortage of organs? It is a transplant surgeon's dream to find an endless supply of organs and tissues that match their recipient. The prospect of transplanting animal organs into humans (xenotransplantation) is increasingly promising, but there are still obstacles to... view more (2002-06-06)

Scientists link another gene to degenerative blindness
Researchers have labored for decades to understand blindness-inducing neurodegenerative diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP).   view more (2006-01-19)

Three Nordic Centres of Excellence in molecular medicine selected
Press release from the Joint Committee of the Nordic Medical Research Councils, the Nordic Council of Ministers and the Nordic Academy for Advanced Study 2004-06-09 Parkinson's, Alzheimer's, stroke, migraine, epilepsy, cancer and autoimmune and metabolic disorders - these are examples of diseases... view more (2004-06-10)

Prion Research Center to open today - Hebrew University-hadassah Medical School Researchers Working To Prevent Mad Cow Disease
Prion Research Center to open today Jerusalem, July 31, 2002 - Scientists around the world are striving to learn as much as possible about the phenomenon that causes mad cow disease so that they will be prepared if and when an epidemic breaks out, according to Dr. Albert Taraboulos of the Institute... view more (2002-07-31)

New compound reduces stroke damage
A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.   view more (2006-05-16)

3-D fruit fly images to benefit brain research
The fragile head and brain of a fly are not easy things to examine but MRC scientists have figured out how to make it a little simpler. And they hope their research will shed light on human disease.   view more (2007-09-05)

3-D forms link antibiotic resistance and brain disease
The story of what makes certain types of bacteria resistant to a specific antibiotic has a sub-plot that gives insight into the cause of a rare form of brain degeneration among children, according to investigators at St. Jude Children's Research Hospital.   view more (2006-08-21)

Redox-active iron is a sensor of cognitive impairment associated with Alzheimer's disease
An innovative discovery has been reported that highlights the problems that oxidative stress resulting from iron cumulated in the human brain can generate in relation with the pathogenesis of Alzheimer's disease (AD), the brain disorder affecting almost 30 million throughout the world.   view more (2008-04-07)

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway
Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.   view more (2008-01-18)

HIV is a 'double hit' to the brain
New evidence reported in the August issue of Cell Stem Cell, a publication of Cell Press, offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits, a condition known as HIV-associated dementia.   view more (2007-08-16)
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