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New prion protein discovered by Canadian scientists may offer insight into mad cow disease
Scientists have discovered a new protein that may offer fresh insights into brain function in mad cow disease. "Our team has defined a second prion protein called 'Shadoo', that exists in addition to the well-known prion protein called 'PrP' " said Professor David Westaway, director of... view more (2007-08-17)

Mayo Clinic research collaboration discovers why some DNA repair fails
Mayo Clinic researchers have discovered the inner workings of a defective DNA repair process and are first to explain why certain mutations are not corrected in cells.   view more (2005-10-04)

Myelin suppresses plasticity in the mature brain
Yale School of Medicine researchers report in Science this week genetic evidence for the hypothesis that myelination, or formation of a protective sheath around a nerve fiber, consolidates neural circuitry by suppressing plasticity in the mature brain.   view more (2005-09-30)

Huntington's disease study shows animal models on target
An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington's Disease (HD) closely resembles that of human HD patients.   view more (2007-08-01)

New discovery may improve treatment of neurodegenerative diseases and type 2 diabetes
The discovery opens the way for new drugs to be designed to treat Parkinson's, type 2 diabetis, Alzheimer's and Creuzfeldt-Jacob disease.   view more (2005-12-15)

Cyanobacteria ("blue-green algae") produce toxin with possible connection to neurodegerative disorders
It is well known that a tiny number of cyanobacteria, previously known as blue-green algae, produce substances that can be toxic to both humans and animals. Now a research team from Sweden, Scotland, and the U.S. has found that a further toxin (BMAA, -methyl amino-alanine) with a possible... view more (2005-04-08)

Prevalence of prenatal brain damage amongst infant deaths investigated
The researchers are currently completing a two-year, Scotland-wide study of the prevalence of prenatal brain damage in almost 400 babies who died around the time of their birth. The next, linked, project will be to look at a possible connection between the apolipoprotein E gene (ApoE) and brain... view more (1999-10-28)

QBI neuroscientists make Alzheimer's disease advance
Queensland Brain Institute (QBI) neuroscientists at UQ have discovered a new way to reduce neuronal loss in the brain of a person with Alzheimer's disease.   view more (2008-06-10)

Nixing immaturity in red blood cells
A process of self-digestion called autophagy prompts the maturation of red blood cells. Without a protein called Nix, the cells would not effectively rid themselves of organelles called mitochondria and consequently become short-lived, leading to anemia, said researchers at Baylor College of... view more (2008-05-05)

Scientists ask whether microscaffolding can help stem cells rebuild brain after stroke damage
Inserting tiny scaffolding into the brain could dramatically reduce damage caused by strokes the UK National Stem Cell Network Annual Science Meeting will hear today (10 April).   view more (2008-04-10)

Early detection of Alzheimer's disease a possibility
Research investigating concentrations of magnetite, a magnetic form of iron, in Alzheimer's disease tissue has produced preliminary results that suggest the possibility of developing a technique to detect Alzheimer's disease before clinical symptoms appear. The research*, published in Biology... view more (2003-04-07)

One hit of crystal meth causes birth defects: U of T study
A single prenatal dose of methamphetamine - commonly known as speed - may be enough to cause long-term neurodevelopmental problems in babies, say University of Toronto researchers.   view more (2005-07-27)

Blood urate levels associated with the progression of Parkinson's disease
Higher blood levels of the compound urate, a salt derived from uric acid that is associated with gout, may be associated with a slower progression of Parkinson's disease.   view more (2008-04-15)

Learning disabilities associated with language problems later in life
Individuals with a neurodegenerative condition affecting language appear more likely to have had a history of learning disabilities than those with other types of dementia or with no cognitive problems, according to a report in the February issue of Archives of Neurology, one of the JAMA/Archives... view more (2008-02-12)

Iron banded worms drying out of blood could be linked to Parkinson's and Alzheimer's
Researchers at the University of Warwick and the Indian Institute of Technology Kanpur have discovered that the mechanism that we rely on to transport iron safely through our blood stream can, in certain circumstances, collapse into a state which grows long worm-like "fibrils" banded by... view more (2008-02-11)

New data on "mad cow" disease
A research team at the University of Navarre has detected the presence of the prion protein in the digestive tract of three animal species: the autochthonous Pyrennean cow, in a primate and in rats. This study is the first to describe the exact location of the "healthy" form of the prion... view more (2004-11-16)

Elevated testosterone kills nerve cells
A Yale School of Medicine study shows for the first time that a high level of testosterone, such as that caused by the use of steroids to increase muscle mass or for replacement therapy, can lead to a catastrophic loss of brain cells.   view more (2006-09-27)

New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity
Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea?   view more (2008-02-25)

Stem cells provide new tool for studying disease and identifying ALS drugs
Results of two studies funded by Project A.L.S. and appearing in today's advance online publication of Nature Neuroscience demonstrate that embryonic stem cells may provide a new tool for studying disease mechanisms and for identifying drugs to slow ALS, also known as Lou Gehrig's disease.   view more (2007-04-17)

Gold nanoparticles, radiation combo may slow Alzheimer's
Chemists in Chile and Spain have identified a new approach for the possible treatment of Alzheimer's disease that they say has the potential to destroy beta-amyloid fibrils and plaque - hypothesized to contribute to the mental decline of Alzheimer's patients.   view more (2006-01-05)

Future therapies for stroke may block cell death
A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University.   view more (2007-06-14)

Scientists produce neurons from human skin
Scientists from Université Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin.   view more (2007-02-23)

Penn researchers discover the powerful tool of simultaneous fMRI and PET imaging
Clinical researchers from the University of Pennsylvania Health System (UPHS) are the first to combine fMRI and PET scanning in radiology, creating a way to compare different measurements of the brain's function concurrently. This analysis could lead to better diagnosis and treatment in patients... view more (2005-10-13)

New research shows how chronic stress worsens neurodegenerative disease course
The evidence is accumulating on how bad stress is for health. Chronic stress can intensify inflammation and increase a person's risk for developing central nervous system infections, neurodegenerative diseases, like multiple sclerosis (MS), and other inflammatory diseases.   view more (2007-08-20)

Structure of important neurotransmitter regulator determined
Researchers from Virginia Tech and the Brookhaven National Laboratory have solved the structure of an enzyme that is critical in the regulation of the neurotransmitter system in the human brain.   view more (2008-02-04)
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