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Neurodegenerative Disease Current Events | Neurodegenerative Disease News
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Journal of Alzheimer's Disease is devoted to metal ions and neurodegenerative diseases
The recent issue of the Journal of Alzheimer's Disease (Volume 8, Issue 2) published by IOS Press is devoted to "Metal Ions and Neurodegenerative Diseases" and presents a collection of important papers dedicated to uncovering the role of various metals in human neurophysiology and neurodegenerative disorders. view more (2006-01-13)
Silencing the cause of mad cow disease
BSE (more commonly known as mad cow disease) and CJD, which is a related disease in humans that can occur spontaneously, be inherited, or be acquired (in some cases probably from cows with BSE), are fatal neurodegenerative diseases. view more (2006-12-04)
Mayo Clinic study using structural MRI may help accurately diagnose dementia patients
A new Mayo Clinic study may help physicians differentially diagnose three common neurodegenerative disorders in the future. view more (2009-07-13)
U of MN researchers link early brain development to adult-onset neurodegenerative disease
Researchers at the University of Minnesota's Institute for Human Genetics have shown for the first time that the severity of an adult neurodegenerative disease is tied to how well the brain developed shortly after birth. view more (2006-11-17)
Drug combinations key in treating neurodegenerative diseases
Combining the benefits of multiple drugs in a single pill may hold the key to treating neurodegenerative diseases, Medical College of Georgia researchers say. view more (2009-02-02)
Cerebrospinal fluid used to deliver therapeutics for Lou Gehrig's disease to brain
Researchers from the University of California, San Diego have shown that instead of trying to deliver therapeutic agents for neurodegenerative diseases across the highly impermeable blood-brain barrier via the blood, therapeutic molecules known as antisense oligonucleotides can be delivered to the brain and spinal cord through the cerebrospinal... view more... (2006-07-28)
New biomarkers could help doctors spot Alzheimer's and other neurodegenerative diseases
Neurodegenerative diseases like Alzheimer's and Parkinson's in their early stages can be difficult for physicians to spot, and many diagnoses are incorrect. view more (2006-08-14)
Protein interactions targets for Huntington disease therapy
The identification of more than 200 new proteins that interact with the mutated protein that causes Huntington's disease opens the door to developing treatments for the fatal neurodegenerative disorder. view more (2007-05-11)
A probable cause for Parkinson's?
Parkinson's, Alzheimer's, Lou Gehrig's disease and other brain disorders are among a growing list of maladies attributed to oxidative stress, the cell damage caused during metabolism when the oxygen in the body assumes ever more chemically reactive forms. view more (2006-06-28)
Scientists on track for early diagnosis of neurological diseases
Possible treatments for fatal neurodegenerative diseases such as CJD, Alzheimer's, Parkinson's could result from University of Edinburgh research to find out how specific proteins cause deterioration in brain function. The scientists have discovered for the first time that protein 14-3-3 plays a key role in the development of certain brain... view more... (2003-07-01)
New hereditary gene linked to Parkinson's disease
UCL scientists have discovered a new gene implicated in the early development of Parkinson's disease. In a study of families with early onset disease, Professor Nick Wood and colleagues at UCL's Institute of Neurology identified a novel gene which produces a malfunctioning protein that could pave the way for new treatments for Parkinson sufferers.... view more... (2004-04-15)
3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually. view more (2008-10-29)
Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy. view more (2006-06-09)
Prions link cholesterol to neurodegeneration
Prion infection of neurons increases the free cholesterol content in cell membranes. A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for cholesterol in other neurodegenerative diseases. view more (2008-02-12)
Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's
Researchers at the Burnham Institute for Medical Research have discovered a mechanistic link between cellular stress caused by free radicals and accumulation of misfolded proteins that lead to nerve cell injury and death in neurodegenerative disorders such as Alzheimer's and Parkinson's Disease. view more (2006-05-25)
Gene therapy slows progression of fatal neurodegenerative disease in children
Gene therapy to replace the faulty CLN2 gene, which causes a neurodegenerative disease that is fatal by age 8-12 years, was able to slow significantly the rate of neurologic decline in treated children. view more (2008-05-14)
Researchers gain insight into mechanism underlying Huntington's
Researchers at the University of Kentucky Markey Cancer Center and Graduate Center for Toxicology (GCT) have gained new insight into the genetic mechanisms underlying Huntington's disease and other neurodegenerative or neuromuscular disorders caused by trinucleotide repeats (or TNRs) in DNA. view more (2009-07-14)
Huntington disease begins to take hold early on
A global analysis of brain proteins over a 10-week period in a mouse model of Huntington Disease has revealed some new insights into this complex neurodegenerative disorder. view more (2009-04-17)
New therapeutic targets for neurodegenerative diseases
The focus of work in the Neurosciences Department's Neurobiology Laboratory at the University of the Basque Country's Faculty of Medicine and Odontology is the investigation of the molecular and cellular bases of neurodegenerative illnesses - those that affect the brain and the spinal cord. view more (2007-05-11)
Vitamin D deficiency may be more common in Parkinson's disease patients
Individuals with Parkinson's disease appear more likely to be vitamin D deficient than healthy adults of the same age or patients with Alzheimer's disease, according to a report in the October issue of Archives of Neurology, one of the JAMA/Archives journals. view more (2008-10-14)
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