Neurodegenerative Disease Current Events | Neurodegenerative Disease News | 10
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Naturally fluorescent molecules may serve as cancer biomarker
Excess amounts of a naturally fluorescent molecule found in all living cells could serve as a natural biomarker for cancer, according to bioengineers. view more (2009-04-03)
"Booster rocket" malfunction implicated in Huntington's disease
CNRS and Inserm research scientists at the Institut Curie have shed new light on the function of huntingtin, the protein whose mutation underlies Huntington's disease. This neurodegenerative disease, like Alzheimer's or Parkinson's, is characterized by the abnormal death of certain neurons. The scientists have discovered that huntingtin, like a... view more... (2004-07-07)
Study links faulty DNA repair to Huntington's disease onset
Huntington's disease, an inherited neurodegenerative disorder that affects roughly 30,000 Americans, is incurable and fatal. view more (2007-04-23)
New research shows how chronic stress worsens neurodegenerative disease course
The evidence is accumulating on how bad stress is for health. Chronic stress can intensify inflammation and increase a person's risk for developing central nervous system infections, neurodegenerative diseases, like multiple sclerosis (MS), and other inflammatory diseases. view more (2007-08-20)
Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection
As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease. view more (2008-04-07)
SIRT1 takes down tumors
Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division. view more (2009-04-13)
Protein can nurture or devastate brain cells, depending on its 'friends,' researchers find
Researchers at UT Southwestern Medical Center have uncovered new insights into the "Dr. Jekyll and Mr. Hyde" nature of a protein that stimulates stem-cell maturation in the brain but, paradoxically, can also lead to nerve-cell damage. view more (2008-11-12)
OHSU research reveals possible future target for delaying or stopping Alzheimer's
Researchers at Oregon Health & Science University's Neurological Sciences Institute (NSI) have located a possible target for future therapies aimed at delaying or stopping Alzheimer's disease. view more (2006-05-02)
UCF Research Links Protein, Stem Cells and Potential Alzheimer's Treatment
A team of scientists led by professor Kiminobu Sugaya at the University of Central Florida may have found a new way to treat Alzheimer's disease. view more (2007-08-07)
Learning disabilities associated with language problems later in life
Individuals with a neurodegenerative condition affecting language appear more likely to have had a history of learning disabilities than those with other types of dementia or with no cognitive problems, according to a report in the February issue of Archives of Neurology, one of the JAMA/Archives journals. view more (2008-02-12)
Promising new drug targets identified for Huntington's disease
Research funded by the Wellcome Trust has provided a number of promising new drug targets for Huntington's disease, a neurodegenerative disease. Scientists at the University of Cambridge have identified a number of candidate drugs to investigate further which encourage cells to "eat" the malformed proteins that lead to the disease. view more (2008-03-24)
Identification of a key gene required for brain neural circuit formation
An international team of scientists, lead by Dr. Frederic Charron at the IRCM, and Drs Ami Okada, Sue McConnell, and Marc Tessier-Lavigne in the USA, have made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. view more (2006-11-02)
Alzheimer's research yields potential drug target
Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer's disease. Scientists say the discovery may lead to new drugs for the disease. view more (2009-07-02)
Gene mutation may influence age at onset of Parkinson's disease
The number of mutations in a gene previously found to be associated with early-onset Parkinson's disease may influence the age at which the condition develops; even individuals who carry just one mutated copy may be more susceptible to Parkinson's disease. view more (2006-06-13)
Not all embryonic stem cell lines are created equal
When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. view more (2007-08-07)
Scientists Reveal Chemical Compound Linked To Increased Heart Risk
Scientists believe that they have found a chemical responsible for increasing cardiovascular risk, it was revealed. And crucially they have identified how it is made and destroyed in the body raising the possibilty that new drugs to reduce the risk of heart disease are around the corner. A team of scientists based at the new British Heart... view more... (2002-01-16)
Single copy of Parkinson's-risk gene mutation may lead to earlier symptom onset
Mutations in a gene already known to play a role in causing an inherited form of Parkinson disease may also influence the age at which symptoms of the neurological disorder appear. While inheriting two abnormal copies of the parkin gene previously had been associated with the development of early-onset Parkinson's. view more (2006-06-13)
Mouse gene suppresses Alzheimer's plaques and tangles
Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. view more (2009-11-12)
New directions in tissue repair and regeneration
PHILOSOPHICAL TRANSACTIONS B MAY ISSUE New directions in tissue repair and regeneration - a discussion meeting issue organised and edited by Jeremy Brockes and Paul Martin This volume will consider new information on regeneration and wound healing as biological mechanisms in a variety of species ranging from the planarian worm which can be... view more... (2004-05-04)
Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease. view more (2007-11-14)
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