Neurodegenerative Disease Current Events | Neurodegenerative Disease News | 3
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Immune cells contribute to the development of Parkinson's disease
Parkinson disease is a neurodegenerative disorder that impairs movement, balance, speech, and other functions. It is characterized by the loss of nerves in the brain that produce a substance known as dopamine. view more (2008-12-23)
Early signs that adult bone-marrow stem cells could regenerate brain tissue (p 1432)
Findings of a preliminary study in this week's issue of THE LANCET suggest that transplanted adult bone-marrow cells could regenerate nerve cells in the brains of human stem-cell recipients. These early findings, if confirmed in future research, have implications for the treatment of neurodegenerative disorders such as Parkinson's disease. Ethical... view more... (2004-04-28)
Yeast model shows promise as Alzheimer's test
A century ago this month, German psychiatrist Alois Alzheimer formally described characteristics of the neurodegenerative disease which ultimately came to bear his name. view more (2006-11-20)
Gene newly linked to inherited ALS may also play role in common dementia
Scientists at Washington University School of Medicine in St. Louis have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig's disease. view more (2008-02-21)
Understanding the Noxious cause of Lou Gehrig's disease
There is no known cure for amyotrophic lateral sclerosis (ALS), often known as Lou Gehrig disease and motor neuron disease. view more (2007-09-14)
Inflammatory response to infection and injury may worsen dementia
Inflammation in the brain resulting from infection or injury may accelerate the progress of dementia, research funded by the Wellcome Trust suggests. view more (2008-09-17)
More brain research suggests
Queensland Brain Institute (QBI) scientists have found another important clue to why nerve cells die in neurodegenerative diseases, based on studies of the developing brain. view more (2008-02-07)
New study of gene evolution could lead to better understanding of neurodegenerative disease
Genetic evolution is strongly shaped by genes' efforts to prevent or tolerate errors in the production of proteins, scientists at The University of Texas at Austin and Harvard University have found. view more (2008-07-25)
Protein plays Jekyll and Hyde role in Lou Gehrig's disease
Amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease, is a fatal neurodegenerative disease caused by the death of motor neurons in the brain and spinal cord that control muscle movements from walking and swallowing to breathing. In a groundbreaking study this week in PLoS Biology, Brandeis and Harvard Medical School... view more... (2008-07-29)
Einstein researchers discover important clue to the cause of Parkinson's disease
A glitch in the mechanism by which cells recycle damaged components may trigger Parkinson's disease, according to a study by scientists at the Albert Einstein College of Medicine of Yeshiva University. view more (2008-01-03)
More genes for Lou Gehrig's disease identified, according to Penn researchers
In recent months a spate of mutations have been found in a disease protein called TDP-43 that is implicated in two neurodegenerative disorders: amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease, and certain types of frontotemporal dementia (FTD). These mutations could potentially become candidates for drug targets. view more (2008-04-08)
Huntington's disease deciphered
Researchers at the University of Illinois at Chicago College of Medicine have discovered how the mutated huntingtin gene acts on the nervous system to create the devastation of Huntington's disease. view more (2009-06-15)
Studying Alzheimer's Disease, Parkinson's Disease and Aging
Studying Alzheimer's Disease, Parkinson's Disease and Aging Human Brain Proteome Project: Defining of Standards and Tasks Proteins serve as Biomarkers of Neurodegenerative Diseases One of the main challenges of this century is the understanding of our brain: Why are we getting senile? Which proteins are altered or modified in brain and spinal cord... view more... (2003-09-11)
Tetanus toxin found to have therapeutic properties
A team of researchers from the Department of Biochemistry and Molecular Biology and the Institute of Neuroscience at the Universitat Autònoma de Barcelona has discovered that tetanus toxin, which causes tetanus, could be extremely useful as a therapy against psychological disorders such as depression, anxiety and anorexia, and to slow... view more... (2005-06-15)
New step in DNA damage response in neurons discovered
Researchers have identified a biochemical switch required for nerve cells to respond to DNA damage. view more (2009-01-20)
New research points toward mechanism of age-onset toxicity of Alzheimer's protein
Like most neurodegenerative diseases, Alzheimer's disease usually appears late in life, raising the question of whether it is a disastrous consequence of aging or if the toxic protein aggregates that cause the disease simply take a long time to form. view more (2006-08-11)
New compound stops brain cell degeneration in Alzheimer's disease
Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease. view more (2006-01-20)
Pitt researchers describe molecular '2-step' leading to protein clumps of Huntington's disease
In a paper published in the early online version of Nature Structural and Molecular Biology, researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that might lead to the formation of pathogenic protein clumps in Huntington's disease, and possibly other movement-related... view more... (2009-03-09)
Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases
A Mayo Clinic-led international consortium has found a mechanism that may help explain Parkinson's and other neurological disorders. view more (2009-01-12)
How small molecule can take apart Alzheimer's disease protein fibers
Researchers from the University of Pennsylvania School of Medicine have shown, in unprecedented detail, how a small molecule is able to selectively take apart abnormally folded protein fibers connected to Alzheimer's disease and prion diseases. view more (2008-05-16)
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