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Engineered stem cells show promise for sneaking drugs into the brain
One of the great challenges for treating Parkinson's diseases and other neurodegenerative disorders is getting medicine to the right place in the brain.   view more (2005-12-15)

Molecular imaging sheds new light on progression of Alzheimer's disease
In the past, physicians were able only to follow the progression of Alzheimer's disease (AD) through careful clinical histories, noting the often subtle changes associated with cognitive decline over a number of years.   view more (2008-06-17)

Research suggests cause of neurodegeneration in Huntington's disease
The severe neurodegeneration associated with Huntington's disease may result from molecular mutations that block the transport of nutrients within cells.   view more (2006-05-31)

Alzheimer's gene identified: study
An international effort led by scientists at the University of Toronto, Columbia University and Boston University has isolated another gene responsible for Alzheimer's disease.   view more (2007-01-15)

Green tea ingredient prevents Alzheimer's-like brain damage in mice
Researchers at the University of South (USF) have found that green tea may offer another potential health benefit - protecting the brain against the ravages of Alzheimer's disease.   view more (2005-09-21)

Scientists clone mice from adult skin stem cells
For cells that hold so much promise, stem cells' potential has so far gone largely untapped. But new research from Rockefeller University and Howard Hughes Medical Institute scientists now shows that adult stem cells taken from skin can be used to clone mice using a procedure called nuclear... view more (2007-02-13)

HU Ph.D. student wins award for 'natural protection' to reduce spread of Alzheimer's disease
Although numerous drugs have been developed over the years to alleviate the symptoms of Alzheimer's disease, there is still no real cure to halt this progressive, neurodegenerative disorder that causes premature death of nerve cells in the deep brain nuclei, leading to dementia and death.   view more (2007-06-12)

Deadly genetic disease prevented before birth in zebrafish
By injecting a customized "genetic patch" into early stage fish embryos, researchers at Washington University School of Medicine in St. Louis were able to correct a genetic mutation so the embryos developed normally.   view more (2008-03-24)

Early environmental exposure may accelerate age-related neurodegeneration
Exposure to iron during the first weeks of life in combination with exposure later in life to a common herbicide may contribute to the subsequent degeneration of brain cells associated with the onset of Parkinson's disease (PD), according to a new study in mice.   view more (2007-06-28)

New technology to speed up research into Huntington's disease
A new tool developed at Cambridge University represents a breakthrough in the race to find treatments to help sufferers with Huntington's disease.   view more (2006-10-09)

Nicotine Found to Protect Against Parkinson's-Like Brain Damage
New research suggests that nicotine treatment protects against the same type of brain damage that occurs in Parkinson's disease.   view more (2006-08-08)

Study finds a high caloric diet may prevent the progression of amyotrophic lateral sclerosis
A recent study directed by the Mount Sinai School of Medicine suggests a ketogenic- high caloric diet may prevent the progression of Amyotrophic Lateral Sclerosis (ALS).   view more (2006-04-18)

Study outlines how stroke, head injury can increase risk of Alzheimer's disease
Researchers from the MassGeneral Institute for Neurodegenerative Disorders (MGH-MIND) have discovered how the death of brain cells caused by a stroke or head injury may cause generation of amyloid-beta protein - the key component of senile plaques seen in the brains of patients with Alzheimer's... view more (2007-06-07)

Strawberry daiquiris — the extra-healthy cocktail?
Strawberries are good for you, but serving them in daiquiri form may make them even healthier, scientists show.   view more (2007-04-20)

St. Jude identifies the specific cell that causes eye cancer, disproving long-held theory
Investigators at St. Jude Children's Research Hospital have identified the cell that gives rise to the eye cancer retinoblastoma, disproving a long-standing principle of nerve growth and development.   view more (2007-10-19)

Newborn neurons like to hang with the 'in' crowd
Like any new kid on the block that tries to fit in, newborn brain cells need to find their place within the existing network of neurons.   view more (2007-05-08)

Different forms of amyloid beta in Alzheimer's disease harm neurons in different ways
Researchers at UC Irvine have shown that different forms of amyloid beta lead to neural damage in different ways, leading to an increasingly complex view of amyloid toxicity in the Alzheimer brain.   view more (2006-06-01)

REM sleep behavior disorder found to be precursor of brain-degenerating diseases later in life
Mayo Clinic sleep medicine specialists have found that almost two-thirds of patients with REM sleep behavior disorder (RBD) develop degenerative brain diseases by approximately 11 years after diagnosis of RBD.   view more (2006-06-19)

Cyanobacteria ("blue-green algae") produce toxin with possible connection to neurodegerative disorders
It is well known that a tiny number of cyanobacteria, previously known as blue-green algae, produce substances that can be toxic to both humans and animals. Now a research team from Sweden, Scotland, and the U.S. has found that a further toxin (BMAA, -methyl amino-alanine) with a possible... view more (2005-04-08)

Prevalence of prenatal brain damage amongst infant deaths investigated
The researchers are currently completing a two-year, Scotland-wide study of the prevalence of prenatal brain damage in almost 400 babies who died around the time of their birth. The next, linked, project will be to look at a possible connection between the apolipoprotein E gene (ApoE) and brain... view more (1999-10-28)

Study Finds Drug May Cut Down Involuntary Movements in Huntington's Disease Patients By 25 Percent
The medication tetrabenazine cut down involuntary movement in patients with Huntington's disease on average by about 25 percent, with many patients experiencing a greater improvement.   view more (2006-02-16)

Penn researchers find potential in yeast for selecting Lou Gehrig's disease drugs
Researchers from the University of Pennsylvania School of Medicine are developing a novel approach to screen for drugs to combat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, using yeast cells.   view more (2008-04-18)

Compound in wine reduces levels of Alzheimer's disease-causing peptides
A study published in the November 11 issue of the Journal of Biological Chemistry shows that resveratrol, a compound found in grapes and red wine, lowers the levels of the amyloid-beta peptides which cause the telltale senile plaques of Alzheimer's disease.   view more (2005-11-04)

Study links Alzheimer's disease to abnormal cell division
A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it.   view more (2006-01-18)

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.   view more (2005-09-22)

UCLA, Italian chemists move closer to solving Lou Gehrig's disease mystery
Chemists from UCLA and the University of Florence in Italy may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a progressive, fatal neurodegenerative disorder that strikes without... view more (2007-06-28)

Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned
Scientists have shown that recently developed mouse breeds that mimic the symptoms of Alzheimer's disease (AD) may not be as effective as previously assumed.   view more (2007-08-17)

MRI study opens door to assessing, preventing dangerous brain iron levels
A magnetic resonance imaging (MRI) study at UCLA opens new doors to assessing and potentially preventing brain iron accumulation associated with risk of developing degenerative brain diseases such as Alzheimer's, Parkinson's and Dementia With Lewy Bodies.   view more (2006-03-27)

The Biochemist, June 2001 Edition, Theme: Take The Strain - Brain Degeneration
Older and wiser - Introduction by Elaine Snell Sadly, in the UK alone, one in every 100 people over the age of 65 years has Parkinson's disease. Globally, the number of people with Alzheimer's disease will double to 30 million in the next 30 years. By the middle of the century, the number of people... view more (2001-06-01)

Discovery offers hope of halting Motor Neurone Disease progression
Scientists have discovered a causal link between the gene for a small protein involved in the formation of blood vessels and the development of some forms of Motor Neurone Disease.   view more (2007-10-05)

Cancer researchers add spice to research against rare neuromuscular disease
Scientists who focus on the molecular signaling that underlies prostate cancer have discovered a compound that shows promise against a debilitating neurodegenerative condition known as Kennedy's disease, which is caused by a mutant gene.   view more (2007-03-21)

Cell's 'power plant' genes raise vision disorder risk
Genetic variation in the DNA of mitochondria - the "power plants" of cells - contributes to a person's risk of developing age-related macular degeneration (AMD), Vanderbilt investigators report May 7 in the journal PLoS ONE.   view more (2008-05-07)

Potential new treatment strategy for Alzheimer's disease and other brain and spinal cord damage
A study led by researchers at the San Francisco VA Medical Center and the University of North Carolina, Chapel Hill has identified several new compounds that could play a role in preventing or treating Alzheimer's disease and other degenerative conditions of the nervous system.   view more (2006-05-19)

History of human cannibalism eats away at researchers
In a new study published by the journal Genome Research, a team of scientists reports that 'mad cow'-like diseases have not been a major force in human history, nor have been cannibalistic rituals that are known to be associated with disease transmission.   view more (2006-01-04)

How the Neuron Sprouts Its Branches
Neurobiologists have gained new insights into how neurons control growth of the intricate tracery of branches called dendrites that enable them to connect with their neighbors.   view more (2005-12-12)

Why fish oil is good for you
It's good news that we are living longer, but bad news that the longer we live, the better our odds of developing late-onset Alzheimer's disease.   view more (2007-12-26)

Vaccine triggers immune response, prevents Alzheimer's
A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer's disease-like pathology in mice without causing inflammation or significant side effects.   view more (2008-05-20)

Future therapies for stroke may block cell death
A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University.   view more (2007-06-14)

Scientists produce neurons from human skin
Scientists from Université Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin.   view more (2007-02-23)

Penn researchers discover the powerful tool of simultaneous fMRI and PET imaging
Clinical researchers from the University of Pennsylvania Health System (UPHS) are the first to combine fMRI and PET scanning in radiology, creating a way to compare different measurements of the brain's function concurrently. This analysis could lead to better diagnosis and treatment in patients... view more (2005-10-13)

Alzheimer's-associated enzyme can disrupt neural activity in the brain
An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures.   view more (2007-06-18)

Geisinger scientist seeks cure for Lou Gehrig's disease, creating device to find treatment
A small tropical fish, the curiosity of a Geisinger research scientist and some college students have created the perfect storm of sorts in an attempt to find a cure for one of the world's most devastating neurological diseases.   view more (2007-07-31)

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway
Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.   view more (2008-01-18)

New technique sheds light on Alzheimer’s and CJD
Researchers using laser light fired at proteins believe they could be close to identifying the molecular architecture that predisposes certain proteins to become ‘corrupted’ and misfold, causing diseases such as Parkinson’s, Alzheimer’s and the spongiform encaphalopathies,... view more (2000-11-16)

Scientists discover age-regulated cellular activities that protect against protein aggregation
Alzheimer's disease now strikes more than one in 30 Americans, and about half the population that lives past 85 acquires Alzheimer's.   view more (2006-08-14)

Lou Gehrig's protein found throughout brain, suggesting effects beyond motor neurons
Two years ago researchers at the University of Pennsylvania School of Medicine discovered that misfolded proteins called TDP-43 accumulated in the motor areas of the brains of patients with amyotropic lateral sclerosis (ALS), or Lou Gehrig's disease.   view more (2008-06-17)

Moonlighting enzyme linked to neurodegenerative disease
Friedreich's ataxia is one of those diseases few have heard of unless you know someone with the condition. For that individual -- usually a child or teenager -- it is devastating.   view more (2007-04-25)

Key brain antioxidant linked to Alzheimer's and Parkinson's
A study conducted at the San Francisco VA Medical Center has identified a protein found in both mice and humans that appears to play a key role in protecting neurons from oxidative stress, a toxic process linked to neurodegenerative illnesses including Alzheimer's and Parkinson's diseases.   view more (2005-12-15)

A possible mechanistic link between stress and the development of Alzheimer tangles
Subjecting mice to repeated emotional stress, the kind we experience in everyday life, may contribute to the accumulation of neurofibrillary tangles, one of the hallmarks of Alzheimer's disease, report researchers at the Salk Institute for Biological Studies.   view more (2007-06-18)

Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E
A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.   view more (2006-05-11)
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