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Neurodegenerative Disease | Neurodegenerative Disease News, Research and Current Events
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Study links faulty DNA repair to Huntington's disease onset
Huntington's disease, an inherited neurodegenerative disorder that affects roughly 30,000 Americans, is incurable and fatal. view more (2007-04-23)
"Booster rocket" malfunction implicated in Huntington's disease
CNRS and Inserm research scientists at the Institut Curie have shed new light on the function of huntingtin, the protein whose mutation underlies Huntington's disease. This neurodegenerative disease, like Alzheimer's or Parkinson's, is characterized by the abnormal death of certain neurons. The... view more (2004-07-07)
A glimmer of hope in the struggle against neurodegenerative diseases: the virtues of proteins that can save dying neurons
Diseases characterized by neurodegeneration affect individuals over 50 years of age and they attack one particular class of neurons in the brain or spinal cord. The research interest of Professor Ann Kato and her team is principally focalized on ALS in which there is a progressive paralysis caused... view more (2002-01-25)
OHSU research reveals possible future target for delaying or stopping Alzheimer's
Researchers at Oregon Health & Science University's Neurological Sciences Institute (NSI) have located a possible target for future therapies aimed at delaying or stopping Alzheimer's disease. view more (2006-05-02)
Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection
As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease. view more (2008-04-07)
New research shows how chronic stress worsens neurodegenerative disease course
The evidence is accumulating on how bad stress is for health. Chronic stress can intensify inflammation and increase a person's risk for developing central nervous system infections, neurodegenerative diseases, like multiple sclerosis (MS), and other inflammatory diseases. view more (2007-08-20)
Promising new drug targets identified for Huntington's disease
Research funded by the Wellcome Trust has provided a number of promising new drug targets for Huntington's disease, a neurodegenerative disease. Scientists at the University of Cambridge have identified a number of candidate drugs to investigate further which encourage cells to "eat" the... view more (2008-03-24)
UCF Research Links Protein, Stem Cells and Potential Alzheimer's Treatment
A team of scientists led by professor Kiminobu Sugaya at the University of Central Florida may have found a new way to treat Alzheimer's disease. view more (2007-08-07)
Gene mutation may influence age at onset of Parkinson's disease
The number of mutations in a gene previously found to be associated with early-onset Parkinson's disease may influence the age at which the condition develops; even individuals who carry just one mutated copy may be more susceptible to Parkinson's disease. view more (2006-06-13)
Learning disabilities associated with language problems later in life
Individuals with a neurodegenerative condition affecting language appear more likely to have had a history of learning disabilities than those with other types of dementia or with no cognitive problems, according to a report in the February issue of Archives of Neurology, one of the JAMA/Archives... view more (2008-02-12)
Scientists Reveal Chemical Compound Linked To Increased Heart Risk
Scientists believe that they have found a chemical responsible for increasing cardiovascular risk, it was revealed. And crucially they have identified how it is made and destroyed in the body raising the possibilty that new drugs to reduce the risk of heart disease are around the corner. A team of... view more (2002-01-16)
Single copy of Parkinson's-risk gene mutation may lead to earlier symptom onset
Mutations in a gene already known to play a role in causing an inherited form of Parkinson disease may also influence the age at which symptoms of the neurological disorder appear. While inheriting two abnormal copies of the parkin gene previously had been associated with the development of... view more (2006-06-13)
Identification of a key gene required for brain neural circuit formation
An international team of scientists, lead by Dr. Frederic Charron at the IRCM, and Drs Ami Okada, Sue McConnell, and Marc Tessier-Lavigne in the USA, have made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. view more (2006-11-02)
Not all embryonic stem cell lines are created equal
When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each... view more (2007-08-07)
New directions in tissue repair and regeneration
PHILOSOPHICAL TRANSACTIONS B MAY ISSUE New directions in tissue repair and regeneration - a discussion meeting issue organised and edited by Jeremy Brockes and Paul Martin This volume will consider new information on regeneration and wound healing as biological mechanisms in a variety of... view more (2004-05-04)
Paradoxical Alzheimer's finding may shed new light on memory loss
Do you remember the seventh song that played on your radio on the way to work yesterday? Most of us don't, thanks to a normal forgetting process that is constantly "cleaning house" - culling inconsequential information from our brains. view more (2008-03-13)
Abnormal glutamine repeats interfere with key transcription factor, leading to neurodegeneration
Although repeating sequences of three nucleotides encoding some of the bodies' 20 amino acids are a normal part of protein composition, abnormal expansion of trinucleotide repeats is the known cause of multiple inherited neurodegenerative disorders, including Huntington disease. view more (2007-11-14)
Researchers explore the emerging role of infection in Alzheimer's disease
A number of chronic diseases are in fact caused by one or more infectious agents. For example, stomach ulcers are caused by Helicobacter pylori, chronic lung disease in newborns and chronic asthma in adults are both caused by Mycoplasmas and Chlamydia pneumonia, while some other pathogens have been... view more (2008-05-23)
Research unveils new hope for deadly childhood disease
Investigators at the University of Rochester Medical Center have uncovered a promising drug therapy that offers a ray of hope for children with Batten disease - a rare neurodegenerative disease that strikes seemingly healthy kids, progressively robs them of their abilities to see, reason and move,... view more (2007-12-13)
New way to diagnose Alzheimer's disease promises earlier treatment
Physicians may be able to detect and treat Alzheimer's Disease (AD) in its earliest stages, when patients are experiencing only mild degrees of cognitive impairment, thanks to new diagnostic criteria proposed by an international group of researchers. view more (2007-09-17)
UK research could lead to new treatments for Parkinson's
A team at the University of Sheffield has received a share of $3.6m from the Michael J. Fox Foundation to research potential causes and treatments for Parkinson's Disease. view more (2005-01-28)
Gene expression levels may reveal stage of Huntington's disease
A survey of the genome of patients with Huntington's Disease (HD) has identified potential markers of the progression of this devastating neurological disorder. view more (2005-08-17)
Gene hunters close in on Lou Gehrig's disease
In the first genome-wide search for the genetic roots of the most common form of amyotrophic lateral sclerosis (ALS), Johns Hopkins scientists have newly identified 34 unique variations in the human genetic code among 276 unrelated subjects with ALS. view more (2007-02-21)
Brittlestar provides new model for stem cell research
The brittlestar, Amphiura filiformis, is a close relative of the starfish and can regenerate lost arms in a matter of weeks. view more (2006-04-10)
Johns Hopkins scientists map brain area that may aid hunt for human brain stem cells
A study led by a Johns Hopkins neurosurgeon has provided the first comprehensive map of a part of the adult human brain containing astrocytes, cells known to produce growth factors critical to the regeneration of damaged neural tissue and that potentially serve as brain stem cells. view more (2006-02-17)
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