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REM sleep behavior disorder found to be precursor of brain-degenerating diseases later in life
Mayo Clinic sleep medicine specialists have found that almost two-thirds of patients with REM sleep behavior disorder (RBD) develop degenerative brain diseases by approximately 11 years after diagnosis of RBD.   view more (2006-06-19)

Prevalence of prenatal brain damage amongst infant deaths investigated
The researchers are currently completing a two-year, Scotland-wide study of the prevalence of prenatal brain damage in almost 400 babies who died around the time of their birth. The next, linked, project will be to look at a possible connection between the apolipoprotein E gene (ApoE) and brain... view more (1999-10-28)

Penn researchers find potential in yeast for selecting Lou Gehrig's disease drugs
Researchers from the University of Pennsylvania School of Medicine are developing a novel approach to screen for drugs to combat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, using yeast cells.   view more (2008-04-18)

Study Finds Drug May Cut Down Involuntary Movements in Huntington's Disease Patients By 25 Percent
The medication tetrabenazine cut down involuntary movement in patients with Huntington's disease on average by about 25 percent, with many patients experiencing a greater improvement.   view more (2006-02-16)

Compound in wine reduces levels of Alzheimer's disease-causing peptides
A study published in the November 11 issue of the Journal of Biological Chemistry shows that resveratrol, a compound found in grapes and red wine, lowers the levels of the amyloid-beta peptides which cause the telltale senile plaques of Alzheimer's disease.   view more (2005-11-04)

Variant of mad cow disease may be transmitted by blood transfusions, according to animal study
Blood transfusions are a valuable treatment mechanism in modern medicine, but can come with the risk of donor disease transmission. Researchers are continually studying the biology of blood products to understand how certain diseases are transmitted in an effort to reduce this risk during blood... view more (2008-08-29)

Data mining detects signs of Lou Gehrig's disease in gene carriers long before symptoms appear
Inspired by the use of microarray chips that look for gene combinations, psychologists are using "pattern array" software to spot movements in rats that might help them predict diseases such as Lou Gehrig's syndrome.   view more (2008-08-04)

Study links Alzheimer's disease to abnormal cell division
A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it.   view more (2006-01-18)

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models
In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.   view more (2005-09-22)

UCLA, Italian chemists move closer to solving Lou Gehrig's disease mystery
Chemists from UCLA and the University of Florence in Italy may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a progressive, fatal neurodegenerative disorder that strikes without... view more (2007-06-28)

Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned
Scientists have shown that recently developed mouse breeds that mimic the symptoms of Alzheimer's disease (AD) may not be as effective as previously assumed.   view more (2007-08-17)

MRI study opens door to assessing, preventing dangerous brain iron levels
A magnetic resonance imaging (MRI) study at UCLA opens new doors to assessing and potentially preventing brain iron accumulation associated with risk of developing degenerative brain diseases such as Alzheimer's, Parkinson's and Dementia With Lewy Bodies.   view more (2006-03-27)

The Biochemist, June 2001 Edition, Theme: Take The Strain - Brain Degeneration
Older and wiser - Introduction by Elaine Snell Sadly, in the UK alone, one in every 100 people over the age of 65 years has Parkinson's disease. Globally, the number of people with Alzheimer's disease will double to 30 million in the next 30 years. By the middle of the century, the number of people... view more (2001-06-01)

Discovery offers hope of halting Motor Neurone Disease progression
Scientists have discovered a causal link between the gene for a small protein involved in the formation of blood vessels and the development of some forms of Motor Neurone Disease.   view more (2007-10-05)

Cancer researchers add spice to research against rare neuromuscular disease
Scientists who focus on the molecular signaling that underlies prostate cancer have discovered a compound that shows promise against a debilitating neurodegenerative condition known as Kennedy's disease, which is caused by a mutant gene.   view more (2007-03-21)

Cell's 'power plant' genes raise vision disorder risk
Genetic variation in the DNA of mitochondria - the "power plants" of cells - contributes to a person's risk of developing age-related macular degeneration (AMD), Vanderbilt investigators report May 7 in the journal PLoS ONE.   view more (2008-05-07)

Potential new treatment strategy for Alzheimer's disease and other brain and spinal cord damage
A study led by researchers at the San Francisco VA Medical Center and the University of North Carolina, Chapel Hill has identified several new compounds that could play a role in preventing or treating Alzheimer's disease and other degenerative conditions of the nervous system.   view more (2006-05-19)

History of human cannibalism eats away at researchers
In a new study published by the journal Genome Research, a team of scientists reports that 'mad cow'-like diseases have not been a major force in human history, nor have been cannibalistic rituals that are known to be associated with disease transmission.   view more (2006-01-04)

How the Neuron Sprouts Its Branches
Neurobiologists have gained new insights into how neurons control growth of the intricate tracery of branches called dendrites that enable them to connect with their neighbors.   view more (2005-12-12)

Why fish oil is good for you
It's good news that we are living longer, but bad news that the longer we live, the better our odds of developing late-onset Alzheimer's disease.   view more (2007-12-26)

Future therapies for stroke may block cell death
A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University.   view more (2007-06-14)

Vaccine triggers immune response, prevents Alzheimer's
A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer's disease-like pathology in mice without causing inflammation or significant side effects.   view more (2008-05-20)

Scientists produce neurons from human skin
Scientists from Université Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin.   view more (2007-02-23)

Penn researchers discover the powerful tool of simultaneous fMRI and PET imaging
Clinical researchers from the University of Pennsylvania Health System (UPHS) are the first to combine fMRI and PET scanning in radiology, creating a way to compare different measurements of the brain's function concurrently. This analysis could lead to better diagnosis and treatment in patients... view more (2005-10-13)

Alzheimer's-associated enzyme can disrupt neural activity in the brain
An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures.   view more (2007-06-18)
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