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Neurodegenerative Diseases Current Events | Neurodegenerative Diseases News

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New biomarkers could help doctors spot Alzheimer's and other neurodegenerative diseases
Neurodegenerative diseases like Alzheimer's and Parkinson's in their early stages can be difficult for physicians to spot, and many diagnoses are incorrect.   view more (2006-08-14)

Silencing the cause of mad cow disease
BSE (more commonly known as mad cow disease) and CJD, which is a related disease in humans that can occur spontaneously, be inherited, or be acquired (in some cases probably from cows with BSE), are fatal neurodegenerative diseases.   view more (2006-12-04)

Cerebrospinal fluid used to deliver therapeutics for Lou Gehrig's disease to brain
Researchers from the University of California, San Diego have shown that instead of trying to deliver therapeutic agents for neurodegenerative diseases across the highly impermeable blood-brain barrier via the blood, therapeutic molecules known as antisense oligonucleotides can be delivered to the... view more (2006-07-28)

Journal of Alzheimer's Disease is devoted to metal ions and neurodegenerative diseases
The recent issue of the Journal of Alzheimer's Disease (Volume 8, Issue 2) published by IOS Press is devoted to "Metal Ions and Neurodegenerative Diseases" and presents a collection of important papers dedicated to uncovering the role of various metals in human neurophysiology and... view more (2006-01-13)

A probable cause for Parkinson's?
Parkinson's, Alzheimer's, Lou Gehrig's disease and other brain disorders are among a growing list of maladies attributed to oxidative stress, the cell damage caused during metabolism when the oxygen in the body assumes ever more chemically reactive forms.   view more (2006-06-28)

Prions link cholesterol to neurodegeneration
Prion infection of neurons increases the free cholesterol content in cell membranes. A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for... view more (2008-02-12)

Scientists on track for early diagnosis of neurological diseases
Possible treatments for fatal neurodegenerative diseases such as CJD, Alzheimer's, Parkinson's could result from University of Edinburgh research to find out how specific proteins cause deterioration in brain function. The scientists have discovered for the first time that protein 14-3-3 plays a... view more (2003-07-01)

Mechanism for neurodenegerative diseases linked to transport proteins
Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.   view more (2006-06-09)

3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually.   view more (2008-10-29)

Scientists link another gene to degenerative blindness
Researchers have labored for decades to understand blindness-inducing neurodegenerative diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP).   view more (2006-01-19)

Key stress protein linked to toxicities responsible for Parkinson's, Alzheimer's
Researchers at the Burnham Institute for Medical Research have discovered a mechanistic link between cellular stress caused by free radicals and accumulation of misfolded proteins that lead to nerve cell injury and death in neurodegenerative disorders such as Alzheimer's and Parkinson's Disease.   view more (2006-05-25)

A clue to core problem of neurodegenerative disease and cell death
Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.   view more (2006-02-10)

Researchers hot on the trail of brain cell degeneration
A research team headed by Academy Research Fellow Michael Courtney has identified a new molecular pathway in neurons. The pathway is a factor in the degeneration of brain cells, which in turn plays an important role in neurological conditions and diseases, such as Alzheimer's disease, epilepsy and... view more (2007-03-20)

U of MN researchers link early brain development to adult-onset neurodegenerative disease
Researchers at the University of Minnesota's Institute for Human Genetics have shown for the first time that the severity of an adult neurodegenerative disease is tied to how well the brain developed shortly after birth.   view more (2006-11-17)

New hereditary gene linked to Parkinson's disease
UCL scientists have discovered a new gene implicated in the early development of Parkinson's disease. In a study of families with early onset disease, Professor Nick Wood and colleagues at UCL's Institute of Neurology identified a novel gene which produces a malfunctioning protein that could pave... view more (2004-04-15)

Scientists encourage cells to make a meal of Huntington's disease
Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.   view more (2007-05-08)

More brain research suggests
Queensland Brain Institute (QBI) scientists have found another important clue to why nerve cells die in neurodegenerative diseases, based on studies of the developing brain.   view more (2008-02-07)

UWM brain research supports drug development from jellyfish protein
With the research support from the University of Wisconsin-Milwaukee, a Wisconsin biotech company has found that a compound from a protein found in jellyfish is neuro-protective and may be effective in treating neurodegenerative diseases.   view more (2006-10-30)

Unexpected similarities between raindrops and proteins
Raindrops and proteins seem to have a lot in common. This has been shown in a new study by scientists at Ume'å University in Sweden. The principle behind the formation of raindrops is very similar to how proteins fold. This knowledge is vital to our understanding of neurodegenerative diseases... view more (2004-05-26)

RNA Toxicity Contributes to Neurodegenerative Disease, University of Pennsylvania Scientists Say
Expanding on prior research performed at the University of Pennsylvania, Penn biologists have determined that faulty RNA, the blueprint that creates mutated, toxic proteins, contributes to a family of neurodegenerative disorders in humans.   view more (2008-05-22)

Protein interactions targets for Huntington disease therapy
The identification of more than 200 new proteins that interact with the mutated protein that causes Huntington's disease opens the door to developing treatments for the fatal neurodegenerative disorder.   view more (2007-05-11)

New therapeutic targets for neurodegenerative diseases
The focus of work in the Neurosciences Department's Neurobiology Laboratory at the University of the Basque Country's Faculty of Medicine and Odontology is the investigation of the molecular and cellular bases of neurodegenerative illnesses - those that affect the brain and the spinal cord.   view more (2007-05-11)

UIC chemists characterize Alzheimer's neurotoxin structure
Amyloid plaques, the hallmark of Alzheimer's disease, are clumps of fiber-like misfolded proteins which many experts think cause this devastating neurodegenerative disease.   view more (2007-12-04)

U. Iowa team identifies genes that improve survival in mice with ALS
University of Iowa researchers investigating the basic biology of cell signaling have made a discovery that may have therapeutic implications for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.   view more (2007-09-14)

Study implicates potassium channel mutations in neurodegeneration and mental retardation
For the first time, researchers have linked mutations in a gene that regulates how potassium enters cells to a neurodegenerative disease and to another disorder that causes mental retardation and coordination problems.   view more (2006-02-27)
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