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Neurodegenerative Diseases Current Events | Neurodegenerative Diseases News | 7

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Mutant gene shatters nerves
If you bend a knee or an elbow, the nerves in your limbs stretch but do not break. A University of Utah study suggests why: A gene produces a springy protein that keeps nerve cells flexible. When the gene was disabled in tiny nematode worms, their nerve cells literally broke.   view more (2007-01-30)

Researchers find potential treatment for Huntington's disease
Investigators at Burnham Institute for Medical Research (Burnham), the University of British Columbia's Centre for Molecular Medicine and Therapeutics and the University of California, San Diego have found that normal synaptic activity in nerve cells (the electrical activity in the brain that allows nerve cells to communicate with one another)... view more... (2009-11-16)

Mad-cow culprit maintains stem cells
What do mad cow disease and stem cell research have in common? Whitehead Institute scientists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain themselves.   view more (2006-01-31)

Leaky blood vessels open up nerve cells to toxic assault in Lou Gehrig's disease
Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience.   view more (2008-04-08)

Mechanism of Alzheimer's suggests combination therapy needed
Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch of therapy may be needed to combat the neurodegenerative disease.   view more (2009-03-18)

Deadly infectious entity of prions discovered
The mysterious, highly infectious prions, which cause the severe destruction of the brain that characterizes "mad cow disease" and several human brain degenerative disorders, can be rendered harmless in the laboratory by a slight alternation of the three-dimensional conformation or shape of the prion protein's structure.   view more (2005-06-10)

Not all embryonic stem cell lines are created equal
When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line.   view more (2007-08-07)

Trembling hands and molecular handshakes
Fragile X tremor/ataxia syndrome (FXTAS) is a recently recognized condition, which is actually one of the most prevalent heritable neurodegenerative diseases.   view more (2009-10-26)

Protein aggregates in Lou Gehrig's disease linked to neuron death
French neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis (ALS) in 1869, but, nearly 140 years later, little is known about the cause of the devastating neurodegenerative disease, and there is no cure   view more (2005-10-27)

Taking the wrinkles out of motoneuronal disease
A winner of UniQuest's 2006 Trailblazer innovation competition, Dr Frederic Meunier, is developing a treatment for motoneuronal diseases based on modifying botox —the popular anti-wrinkle treatment.   view more (2006-07-06)

Researchers explore the emerging role of infection in Alzheimer's disease
A number of chronic diseases are in fact caused by one or more infectious agents. For example, stomach ulcers are caused by Helicobacter pylori, chronic lung disease in newborns and chronic asthma in adults are both caused by Mycoplasmas and Chlamydia pneumonia, while some other pathogens have been associated with atherosclerosis.   view more (2008-05-23)

New insights into the diversity of Creutzfeldt-Jakob disease agents
Researchers from the United Kingdom and France have identified four separate biochemical subgroups in a selection of cases of Creutzfeldt-Jakob disease.   view more (2008-03-18)

Newly discovered antibody may be body's natural defense against Alzheimer's
In an important advance in the battle against Alzheimer's disease, physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have identified naturally occurring antibodies in human blood that may help to defend against this form of dementia as well as other neurodegenerative diseases.   view more (2007-06-12)

Parasitic tropical diseases in the Americas, a legacy of slavery, can be eliminated
Although it has been speculated for more than a century that the slave trade was responsible for bringing many tropical diseases to the Americas, only recently has convincing evidence shown that lymphatic filariasis (elephantiasis), schistosomiasis, and onchocerciasis (river blindness) originated in this way.   view more (2007-11-07)

Protein can nurture or devastate brain cells, depending on its 'friends,' researchers find
Researchers at UT Southwestern Medical Center have uncovered new insights into the "Dr. Jekyll and Mr. Hyde" nature of a protein that stimulates stem-cell maturation in the brain but, paradoxically, can also lead to nerve-cell damage.   view more (2008-11-12)

A picture of progress: PET imaging and biomarkers explored at ACS meeting
Doctors often have wished they could dispense with diagnostic guesswork and simply peer inside a human body to see the effects of a disease or if a particular medicine really works.   view more (2005-09-01)

Purdue scientists may have found key to halting spinal cord damage
Purdue University researchers may have isolated the substance most responsible for the tissue damage that follows initial spinal cord injury, a discovery that could also improve treatments for a host of other neurodegenerative conditions.   view more (2005-06-21)

Government cash injection for University spin-out company's stem cell research
A spin-out company from the University of Nottingham has been awarded around £250,000 of Government funding to develop innovative stem cell therapies that could one day provide new treatments for patients suffering from illnesses including Parkinson's disease and stroke.   view more (2005-01-24)

NJIT professor finds engineering technique to identify disease-causing genes
Scientists believe that complex diseases such as schizophrenia, major depression and cancer are not caused by one, but a multitude of dysfunctional genes.   view more (2008-10-29)

Weizmann scientists discover a new line of communication between nervous system cells
In a host of neurological diseases, including multiple sclerosis (MS) and several neuropathies, the protective covering surrounding the nerves - an insulating material called myelin - is damaged.   view more (2007-06-27)
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