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Demystifying Irritable Bowel Syndrome (p 555)
A seminar in this week's issue of THE LANCET examines the history, epidemiology, and different treatment options for one of the most misunderstood medical complaints-irritable bowel syndrome (IBS). Nicholas Talley from the University of Sydney, Australia, and Robin Spiller from Queens Medical... view more (2002-08-14)

Gene therapy slows progression of fatal neurodegenerative disease in children
Gene therapy to replace the faulty CLN2 gene, which causes a neurodegenerative disease that is fatal by age 8-12 years, was able to slow significantly the rate of neurologic decline in treated children.   view more (2008-05-14)

Eye test causes severe lethargy in infants
New research suggests that an eyedrop used to diagnose a rare syndrome in infants can cause severe lethargy lasting up to 10 hours and requiring hospital admission and oxygen administration.   view more (2007-07-17)

Post-combat syndromes are not unique to the Gulf war
Post-combat syndromes are not unique to the Gulf war, but have arisen after all major wars over the past century, finds a study in this week's BMJ. Records for 1,856 British servicemen were randomly selected from war pension files. The research team identified three clusters of post-combat... view more (2002-02-06)

Study warns of growing cardiovascular disease epidemic in China
As more people in China adopt Western diets and lifestyles, many are developing a cluster of cardiovascular disease risk factors.   view more (2006-04-14)

Drosophila drug screen for fragile X syndrome finds promising compounds and potential drug targets
Scientists using a new drug screening method in Drosophila (fruit flies), have identified several drugs and small molecules that reverse the features of fragile X syndrome -- a frequent form of mental retardation and one of the leading known causes of autism.   view more (2008-03-10)

Scientists identify new gene responsible for puberty disorders
A new gene responsible for some puberty disorders has been identified by Medical College of Georgia researchers.    view more (2008-10-28)

A rainbow of methods promises insights into biological processes and diseases
Physical alterations of DNA in chromosomes can cause serious diseases such as Down syndrome, Prader-Willi syndrome, or cancer.   view more (2007-05-02)

Finding that could shed light on 'golden staph,' candida and allergies
Recent scientific findings explain why patients with a rare immunodeficiency disorder are unusually susceptible to certain common infections. By revealing the exact molecular mechanisms involved, they also give us clues as to why some 'healthy' people are more prone to these infections than others,... view more (2008-07-01)

Metabolic syndrome heightens risk for development
Researchers at UT Southwestern Medical Center have found that patients suffering from the metabolic syndrome - a cluster of conditions that increases the risk for heart disease, stroke and diabetes - also have a propensity to develop highly acidic urine, which increases the risk of developing... view more (2007-09-14)

Hit-and-run injury to the brain
A seven-year tracking study has prompted scientists to suggest that chronic fatigue syndrome could be the result of brain injuries inflicted during the early stages of glandular fever.   view more (2006-03-02)

New mechanism found for neurodegenerative effects of amphetamines in mice
University of Toronto researchers have discovered a new mechanism for the neurodegenerative effects of amphetamines.   view more (2006-04-06)

Increased cognitive control in Tourette's syndrome
Though the repetitive vocal and motor tics characteristic of Tourette's syndrome may suggest an inability to control involuntary actions at the cognitive level, researchers have now found evidence that young people with Tourette's syndrome actually exhibit a greater level of cognitive control over... view more (2006-03-21)

Deep brain mapping to isolate evidence of Gulf War syndrome
Researchers at Southern Methodist University in Dallas are pioneering the use of spatial statistical modeling to analyze brain scan data from Persian Gulf War veterans, aiming to pinpoint specific areas of the their brains affected by Gulf War Syndrome.   view more (2008-11-20)

A different parenthood?
Becoming a parent changes most people's lives. To become a parent of a daughter with a sex chromosome deviation such as Turner syndrome entails further changes. These parents have to create their parenthood taking into consideration the new situation that parenting brings with it and the special... view more (2003-04-15)

Metabolic syndrome identified as risk factor for kidney-pancreas transplant patients
A three-year multi-center study of kidney-pancreas transplant recipients has identified a new risk factor for impaired kidney function, which may help physicians refine their treatment strategies.   view more (2006-01-23)

New mutation causing tumours in the endocrine system
   view more (1999-03-16)

Restricted fetal growth increases risk of irritable bowel syndrome
Babies weighing less than the standard weight seem to be at significantly greater risk of developing irritable bowel syndrome or IBS, suggests research published ahead of print in the journal Gut.   view more (2006-09-28)

REM sleep behaviour disorder is an early marker of neurodegenerative diseases
The front page of the July 2006 issue of The Lancet Neurology, the journal with the highest international impact, contains a work that shows the relationship between disorders during REM sleep and future neurodegenerative pathologies.   view more (2006-06-29)

Human RecQ helicases, homologous recombination and genomic instability
Two independent papers in the December 1st issue of G&D detail how human RecQ helicases regulate homologous recombination and protect genome stability.   view more (2007-11-15)

'QUADRUPLE TEST' OFFERS BEST PREDICTION FOR DOWN'S SYNDROME (pp 794, 835)
Authors of a research letter in this week's issue of THE LANCET highlight how screening for Down's syndrome based on maternal age and four markers in maternal blood should be used worldwide-the quadruple test is far more effective than screening based on maternal age alone. Screening for Down's... view more (2003-03-05)

Researchers hot on the trail of brain cell degeneration
A research team headed by Academy Research Fellow Michael Courtney has identified a new molecular pathway in neurons. The pathway is a factor in the degeneration of brain cells, which in turn plays an important role in neurological conditions and diseases, such as Alzheimer's disease, epilepsy and... view more (2007-03-20)

Are New Functional Medical Disorders A Manifestation Of Environmental Toxicity?
In recent years there has been the emergence of a number of new illnesses that are attributed to environmental factors: multiple chemical sensitivity, syndrome related to dental amalgam and silicone breats implant, electrical hypersensitivity, sick-building syndrome, toner-related illness, and so... view more (2003-09-01)

Best antenatal screening: study results
A study of about 50,000 pregnant women has shown that the integrated test for Down's syndrome offers a "significantly higher" level of safety than the screening available to most women in the UK. The study, which will be reported in the June Journal of Medical Screening, was carried out... view more (2003-06-02)

Gene discovery may shed light on kidney disease
In a finding that may have broader implications for understanding kidney disorders, genetics researchers at The Children's Hospital of Philadelphia have identified a second gene that gives rise to Alagille syndrome, a genetic developmental disease that affects multiple organs.   view more (2006-08-01)
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