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Neuronal Regulator Current Events | Neuronal Regulator News | 2
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Insight into dopamine role suggests new treatment pathway for Parkinson's
Dopamine (DA) not only functions as a neurotransmitter, a chemical messenger between neurons by which one neuron triggers another, researchers have found.   view more (2006-10-19)

Alzheimer's-associated enzyme can disrupt neural activity in the brain
An enzyme involved in the formation of the amyloid-beta protein associated with Alzheimer's disease can also alter the mechanism by which signals are transmitted between brain cells, the disruption of which can cause seizures.   view more (2007-06-18)

3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually.   view more (2008-10-29)

Weill Cornell Team Discovers How Brain's Own tPA Helps Regulate Blood Flow to Neurons
The human brain contains its own store of a powerful enzyme (and stroke drug) called tissue plasminogen activator (tPA), which appears to be a key regulator of blood flow to brain cells, a team at the Weill Cornell Medical College in New York City reports.   view more (2008-01-18)

Opiates and cannaboids: the fight against pain
Opiates and cannaboids, apart from being drugs, have curative properties. Thus, opiates (morphine, methadone, etc.) have been used for some time as a pain-reducer and many cannaboids have also analgesic properties. Regarding their curative aspects, it is very important to know the effects produced... view more (2003-03-18)

Telling axons where to go - and grow
In a recent study, Dr. Ingolf Bach and colleagues from the University of Massachusetts Medical School, Worcester and the University of Hamburg (Germany) describe a novel role for the ubiquitin/proteosome protein degradation pathway in the regulation of local actin dynamics in neurons.   view more (2005-10-03)

Study provides insight into how the brain loses plasticity of youth
A protein once thought to play a role only in the immune system could hold a clue to one of the great puzzles of neuroscience: how do the highly malleable and plastic brains of youth settle down into a relatively stable adult set of neuronal connections?   view more (2006-08-21)

No 'convincing evidence' that glitazones work better than older diabetes drugs
There is no convincing evidence that the newer class of diabetes drugs, known as glitazones, offer real advantages over other diabetes drugs, when used on their own, concludes the Drug and Therapeutics Bulletin (DTB).   view more (2008-04-10)

New molecular insight into vertebrate brain development
In the December 1st issue of G&D, Dr. Fred H. Gage (The Salk Institute for Biological Studies) and colleagues reveal a role for the Hippo signaling pathway in the regulation of vertebrate neural development, identifying new factors - and potential therapeutic targets - that may be involved in... view more (2008-11-18)

Eating and body weight regulated by specific neurons
Researchers at Yale School of Medicine provide direct evidence that two parts of a neuronal system, one that promotes eating and another that suppresses eating, are critical for the acute regulation of eating and body weight.   view more (2005-09-14)

Taking the wrinkles out of motoneuronal disease
A winner of UniQuest's 2006 Trailblazer innovation competition, Dr Frederic Meunier, is developing a treatment for motoneuronal diseases based on modifying botox —the popular anti-wrinkle treatment.   view more (2006-07-06)

New insight into the genetics of brain tumor formation
In a G&D paper published online ahead of its April 1 print publication date, Dr. William Kaelin (Dana Farber Cancer Institute) and colleagues identify a potential new neuronal tumor suppressor.   view more (2008-03-18)

Insights into activity-dependent neuronal growth through RSRF-supported research
Brain-derived neurotrophic factor (BDNF) has been a subject of keen interest in neuroscientific circles for several years, turning up in studies of conditions ranging from central hypoventilation syndrome to obsessive-compulsive disorder, depression, bipolar disorder and schizophrenia - a range of... view more (2006-10-23)

Selective amnesia — How a traumatic memory can be wiped out
French CNRS scientists in collaboration have shown that a memory of a traumatic event can be wiped out, although other, associated recollections remain intact.   view more (2007-04-02)

Novel connection found between biological clock and cancer
Dartmouth Medical School geneticists have discovered that DNA damage resets the cellular circadian clock, suggesting links among circadian timing, the cycle of cell division, and the propensity for cancer.   view more (2006-06-30)

Master regulatory gene of epithelial stem cells identified
The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes. A new study from Harvard Medical School published in the May 4 issue of Cell, however, identifies a "master regulator" of this regeneration process not only for skin, but for many epithelial... view more (2007-05-04)

Gene-regulating enzyme is also a target for anti-depressive drugs
In 2005, professor Ramin Shiekhattar, Ph.D., at The Wistar Institute and his colleagues reported details about an enzyme involved in appropriately repressing sets of neuronal genes in non-neuronal cells.   view more (2006-06-26)

A new pathway for halting neuronal death in Huntington's disease
The body is an extremely complex puzzle in which every piece plays a critical role. Should pieces disappear harmony is compromised. Such is the case with certain neurodegenerative diseases; when neurons suddenly die, the body's ability to function properly is jeopardized. CNRS (1) and INSERM... view more (2002-06-12)

Overexcited neurons not good for cell health
Neurotransmitters have consequences. They initiate events that are critical to a healthy life, giving us the ability to move, to talk, to breathe, to think. But that's if the neurotransmitters are getting it right and sending proper signals downstream to muscle cells, neurons or other cells.   view more (2007-12-18)

Hopkins study suggests commercially available antibiotic may help fight dementia in HIV patients
An antibiotic commonly used to treat a variety of serious infections may also help prevent dementia in HIV patients, according to a test-tube study of human brain cells by Johns Hopkins University School of Medicine neurologist Jeffrey Rumbaugh, M.D., Ph.D.   view more (2006-04-06)

How Rett Syndrome mutation targets the brain
Researchers have pinpointed why mutations that cause Rett Syndrome (RTT)-among the leading causes of mental retardation in females-specifically target the brain rather than other body tissues.   view more (2006-10-19)

Neurons find their place in the developing nervous system with the help of a sticky molecule
The brain, that exquisite network of billions of communicating cells, starts to take form with the genesis of nerve cells. Most newborn nerve cells, also called neurons, must travel from their birthplace to the position they will occupy in the adult brain.   view more (2006-04-26)

Little Crashes Could Protect Stock Market
EMBARGOED UNTIL WEDNESDAY 7 AUGUST 2002 19:00 BST UK CONTACT - Claire Bowles, New Scientist Press Office, London: Tel: +44(0)20 7331 2751 or email claire.bowles@rbi.co.uk WALL STREET`S sneezing fit continues, and the rest of the world can`t shake off its cold. Could the answer be to "immunise" the... view more (2002-08-07)

Scientists discover basic defect in cystic fibrosis airway glands
Scientists at Stanford University have determined that the buildup of sticky mucus found in cystic fibrosis is caused by a loss in the epithelial cell's ability to secrete fluid.   view more (2006-03-20)

Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
For more than 25 years, stem cells have been defined based on what they can become: more of themselves, as well as multiple different specialized cell types.   view more (2007-06-20)
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