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Detailed 3-D image catches a key regulator of neural stem cell differentiation in action
Researchers at the Salk Institute for Biological Studies in collaboration with scientists at the University of California, San Diego (UCSD) took a high resolution "action shot" of a protein switch that plays a crucial role in the development of the nervous system.   view more (2006-12-08)

Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments
UC Irvine School of Medicine researchers have discovered how new neurons born from endogenous neural stem cells are sent to regions of the brain where they can replace old and dying cells, a finding that suggests how stem cell therapies can be specifically targeted to brain regions affected by... view more (2005-06-24)

Protein protects against nerve degeneration
A protein called NMNAT protects against nerve cell degeneration in fruit flies and mice, said Baylor College of Medicine researchers in a report in the Public Library of Science Biology that appears online today.   view more (2006-12-01)

HFI-1 gene has key role in both oxygen sensing, heat shock pathway
University of Oregon researchers have found an unexpected regulatory link between cellular responses to hypoxia and heat shock. Central to the discovery is a gene known as Hypoxia-Inducible Factor-1 (HIF-1) that is critical for both normal and pathological changes, making it a potential target for... view more (2006-10-26)

Brain compensatory mechanisms enhance the recovery from spinal cord injury
A research team led by Tadashi Isa, a professor at the Japanese National Institute for Physiological Sciences, NIPS (SEIRIKEN), and Dr. Yukio Nishimura (University of Washington, Seattle), have found that brain compensatory mechanisms contribute to recovery from spinal cord injury.   view more (2007-11-16)

Alcoholism may cause decreased density of neurons in the orbitofrontal cortex
Previous research has shown that alcoholism can cause damage to certain brain regions, including reduced metabolism, blood flow and tissue volume, as well as a reduced density of neurons and glial cells.   view more (2006-10-25)

Relationship between environmental stress and cancer elucidated
One way environmental stress causes cancer is by reducing the activity level of an enzyme that causes cell death, researchers say.   view more (2007-11-06)

Making the connection between a sound and a reward changes brain and behavior
If you've ever wondered how you recognize your mother's voice without seeing her face or how you discern your cell phone's ring in a crowded room, researchers may have another piece of the answer.   view more (2006-10-23)

Gene controlling circadian rhythms linked to drug addiction, UT Southwestern researchers find
The gene that regulates the body's main biological clocks also may play a pivotal role in drug addiction, researchers at UT Southwestern Medical Center have found.   view more (2005-06-14)

Amateur boxing linked to brain cell injury
A study of 14 Swedish amateur boxers suggests that they have higher levels of certain chemicals in their cerebrospinal fluid in the days following a bout, indicating injuries to neurons and other cells important to brain function.   view more (2006-09-12)

Regulatory pathway in brain development possible basis for malformations
Researchers at the University of California, San Diego (UCSD) School of Medicine have identified a genetic regulator of brain development that sheds new light on how immature neural cells choose between proliferation and differentiation.   view more (2006-12-05)

Gladstone researchers identify new drug target for Alzheimer's disease
Researchers at the Gladstone Institute of Neurological Disease have identified a potential new way to stop brain cell death related to Alzheimer's disease.   view more (2005-12-02)

Study finds a high caloric diet may prevent the progression of amyotrophic lateral sclerosis
A recent study directed by the Mount Sinai School of Medicine suggests a ketogenic- high caloric diet may prevent the progression of Amyotrophic Lateral Sclerosis (ALS).   view more (2006-04-18)

Cancer researchers found a new mechanism potentially explaining evolution of signalling pathways
Cancer researchers at the University of Helsinki, in trying to find a novel tumor suppressor gene, instead found an important evolutionary change that occurred in a key developmental signalling pathway.   view more (2006-02-08)

Coffee: a cause of neonatal seizures?
Epidemiological observations raised the possibility that coffee was deleterious for newborn babies. For the last ten years the American Food and Drug Administration (FDA) has therefore recommended that pregnant women limit their consumption of coffee.   view more (1999-06-16)

Study implicates defective synapse generator in onset of Alzheimer's
A new UCLA/Veterans Affairs study implicates defects in the machinery that creates connections between brain cells as responsible for the onset of Alzheimer disease.   view more (2006-01-27)

Researchers reveal types of genes necessary for brain development
Researchers from Harvard Medical School and Brandeis University have successfully completed a full-genome RNAi screen in neurons, showing what types of genes are necessary for brain development. Details of the screen and its novel methodology are published July 4th in the open-access journal PLoS... view more (2008-07-08)

Linking 2 molecular pieces of the Alzheimer's puzzle
Researchers have uncovered a biological link between the protein whose mutation causes early-onset Alzheimer's disease (AD) and a gene variant linked to late-onset AD. The researchers said their finding could lead to new approaches to treating AD.   view more (2007-10-04)

MIT: Stem-cell therapies for brain more complicated than thought
An MIT research team's latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought.   view more (2007-11-28)

Untangling a pathology of Alzheimer's
Researchers have uncovered what appears to be a natural protective mechanism against a central cause of neuronal death in Alzheimer's and similar neurodegenerative diseases.   view more (2006-09-07)

The cause of all hereditary sensory and autonomic neuropathy type II cases has been established
A major discovery that details the existence of a neuronal specific form of the WNK1 gene, henceforth referred to as the WNK1/HSN2 isoform, was recently completed by the research group of Dr. Guy A. Rouleau and published in the scientific journal The Journal of Clinical Investigation.   view more (2008-06-11)

'Gateway' gene discovered for brain cancer
Researchers have discovered that the same genetic regulator that triggers growth of stem cells during brain development also plays a central role in the development of the lethal brain cancer malignant glioma.   view more (2007-02-15)

Gene therapy slows progression of fatal neurodegenerative disease in children
Gene therapy to replace the faulty CLN2 gene, which causes a neurodegenerative disease that is fatal by age 8-12 years, was able to slow significantly the rate of neurologic decline in treated children.   view more (2008-05-14)

How the Neuron Sprouts Its Branches
Neurobiologists have gained new insights into how neurons control growth of the intricate tracery of branches called dendrites that enable them to connect with their neighbors.   view more (2005-12-12)

How Candida albicans transforms from its normally benign form into life-threatening form
Researchers at the Agency for Science, Technology and Research's (A*STAR) Institute of Molecular and Cell Biology (IMCB) have discovered new molecular mechanisms that provide a more detailed understanding of how the normally benign Dr. Jekyll-like fungus known as Candida albicans transforms into a... view more (2007-10-05)
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