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Liver fibrosis will be treated by a potential target
The outcome of hepatitis is either self recovery or its development into liver fibrosis or, further, liver cirrhosis. Liver fibrosis is the early pathological process of cirrhosis, which is considered a reversible, wound-healing response. Since no ideal drug is available for its therapy, liver... view more (2007-10-17)

Novel Discoveries Leading To Targeted Treatment Of Lymphatic Diseases
A gene responsible for lymphatic vessel formation Novel discoveries at the University of Helsinki, Finland, about the development of the lymphatic network may help researchers to better understand the mechanisms of cancer and its metastasis, and also diseases such as lymphedema, wound healing and... view more (2003-11-20)

Electricity: Transforming our current system
A long-term replacement strategy for Britain's ageing electricity network is being developed. It involves the use of computer modelling techniques to simulate the conditions under which a new system would operate. This would indicate how investment should be made in the electricity distribution... view more (2001-12-05)

New Mount Sinai research tracks effects of addictive drugs on brain
Mount Sinai researchers may have unlocked the key to better understanding the effect addictive drugs have on the human brain.   view more (2008-05-16)

Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E
A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.   view more (2006-05-11)

Scientists Shed Light on Long-Distance Signaling in Developing Neurons
A longstanding puzzle in neurodevelopment may have yielded up a key secret. A team led by scientists at Weill Cornell Medical College says they have determined how events at the very tips of the developing neuron's long, skinny axon affect gene transcription back in the cell's distant nucleus.   view more (2008-02-20)

Most important actors in the growth process of neurons identified
Defects in the growth process of our neurons often underlie brain or nerve diseases, such as Alzheimer's disease or multiple sclerosis.   view more (2006-10-12)

New compound stops brain cell degeneration in Alzheimer's disease
Drug discovery researchers at Northwestern University have developed a novel orally administered compound specifically targeted to suppress brain cell inflammation and neuron loss associated with Alzheimer's disease.   view more (2006-01-20)

Second low-oxygen pathway hints at cancer, cardiovascular disease physiology
Researchers at the University of Pennsylvania School of Medicine have identified a second molecular pathway that promotes cell survival in low-oxygen conditions.   view more (2006-02-17)

Company Environmental Management Systems cannot be trusted to displace regulation - not yet
The certification of environmental management systems (EMSs) must be improved if they are to become robust enough to replace inspection by a public sector regulator, warns a paper published jointly by the Policy Studies Institute and the Environment Agency. Having good environmental practices... view more (2003-08-12)

Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity
Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk. Available antipsychotic medications treat some of the symptoms of schizophrenia, but are typically effective in only a subset of patients.   view more (2008-01-09)

A Neural Mosaic of Tones
The brain filters what we hear. It can do this in part because particular groups of neurons react to specific frequencies of sound.   view more (2006-06-23)

New findings help explain how brain pathways control body weight
A study led by a scientific team at Beth Israel Deaconess Medical Center (BIDMC) provides another important step in our understanding of the critical role that the brain's molecular pathways play in the development of obesity and related disorders.   view more (2005-11-04)

Fish really is brain food
Researchers at the University of Bristol have found that mums-to-be who eat oily fish such as sardines and mackerel have children whose visual development is better. This positive association was also seen for breastfeeding. The findings were announced by Dr Cathy Williams, the eye expert on the... view more (2001-02-01)

Protein amplification in melanoma is possible drug target
Researchers have pinpointed specific gene and protein over-production in metastatic melanoma, pointing the way to a possible new drug target, according to a study published in Nature July 7.   view more (2005-07-11)

Neurotransmitters in biopolymers stimulate nerve regeneration
Research reported December 11 in the journal Advanced Materials describes a potentially promising strategy for encouraging the regeneration of damaged central nervous system cells known as neurons.   view more (2007-12-12)

Controlling body size by regulating the number of cells
Why are elephants bigger than mice? The main reason is that mice have fewer cells. Research published in Journal of Biology this week uncovers a key pathway that controls the number of cells in an animal, thereby controlling its size. Ernst Hafen and his colleagues from the University of... view more (2003-08-05)

Food cue-related brain activity linked to obesity?
A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today in BMC Biology suggests.   view more (2007-04-27)

Scientists solve structure of gene regulator that plays key role in cancer
Scientists at The Wistar Institute have collaborated on a major advance in understanding a gene regulator that contributes to some of the deadliest cancers in humans. The culmination of 10 years' work, their research paves the way for the development of new cancer therapies.   view more (2008-02-14)

Enhanced environment restores memory in mice with neurodegeneration
Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli.   view more (2007-04-30)

Unexpected finding of molecule's dual role in mice may open new avenue to cholesterol reduction
Researchers have discovered an unknown regulator of fat and cholesterol production in the liver of mice, a significant finding that could lead to new therapies for lowering unhealthy blood levels of cholesterol and fats.   view more (2008-06-13)

Quicker and easier rehabilitation following a stroke
By artificially vibrating certain muscle parts, the brain areas and neuronal pathways responsible for movement can be trained. This has the potential to help stroke patients recover their mobility more quickly. These are the results of PhD research by Maarten Steyvers of the Department of... view more (2004-06-11)

Scripps Florida scientists develop a process to disrupt hepatitis C virion production
HCV is a significant human pathogen, infecting more than three percent of the world's population. The incidence of infection in the United States has been estimated to be as high as 4 million cases.   view more (2008-03-24)

MIT researcher finds neuron growth in adult brain
Despite the prevailing belief that adult brain cells don't grow, a researcher at MIT's Picower Institute for Learning and Memory reports in the Dec. 27 issue of Public Library of Science (PLoS) Biology that structural remodeling of neurons does in fact occur in mature brains.   view more (2005-12-27)

A glimmer of hope in the struggle against neurodegenerative diseases: the virtues of proteins that can save dying neurons
Diseases characterized by neurodegeneration affect individuals over 50 years of age and they attack one particular class of neurons in the brain or spinal cord. The research interest of Professor Ann Kato and her team is principally focalized on ALS in which there is a progressive paralysis caused... view more (2002-01-25)
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