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Lou Gehrig's protein found throughout brain, suggesting effects beyond motor neurons
Two years ago researchers at the University of Pennsylvania School of Medicine discovered that misfolded proteins called TDP-43 accumulated in the motor areas of the brains of patients with amyotropic lateral sclerosis (ALS), or Lou Gehrig's disease. view more (2008-06-17)
Key brain antioxidant linked to Alzheimer's and Parkinson's
A study conducted at the San Francisco VA Medical Center has identified a protein found in both mice and humans that appears to play a key role in protecting neurons from oxidative stress, a toxic process linked to neurodegenerative illnesses including Alzheimer's and Parkinson's diseases. view more (2005-12-15)
Understanding Fragile X syndrome with the blink of an eye
While researchers have long known the genetic defect underlying Fragile X syndrome, they are still tracing how that defect creates the complex mix of mental retardation, hyperactive behavior, attention deficits, and other problems in the disorder. view more (2005-08-04)
Alzheimer's disease progresses more rapidly in highly educated people
High levels of education may help ward off Alzheimer's disease, but they also speed up its progression once developed, reveals research in the Journal of Neurology Neurosurgery and Psychiatry. view more (2006-02-16)
Using Synthetic Evolution to Study the Brain: Researchers Model Key Part of Neurons
The human brain has evolved over millions of years to become a vast network of billions of neurons and synaptic connections. Understanding it is one of humankind's greatest pursuits. view more (2009-10-05)
Claudin 11 stops the leaks in neuronal myelin sheaths
Devaux and Gow demonstrate how a tight junction protein called claudin 11 makes the neuronal myelin sheath a snug fit. view more (2008-12-01)
UCR researchers show how the brain turns on innate behavior
UCR researchers have made a major leap forward in understanding how the brain programs innate behavior. view more (2006-07-28)
This is your brain on fatty acids
Saturated fats have a deservedly bad reputation, but Johns Hopkins scientists have discovered that a sticky lipid occurring naturally at high levels in the brain may help us memorize grandma's recipe for cinnamon buns, as well as recall how, decades ago, she served them up steaming from the oven. view more (2009-11-02)
Capturing the birth of a synapse
Researchers have identified the locking mechanism that allows some neurons to form synapses to pass along essential information. view more (2009-05-27)
'Lab on a chip' mimics brain chemistry
Johns Hopkins researchers from the Whiting School of Engineering and the School of Medicine have devised a micro-scale tool - a lab on a chip - designed to mimic the chemical complexities of the brain. The system should help scientists better understand how nerve cells in the brain work together to form the nervous system. view more (2008-02-13)
Case biologists show that what a neuron can do is a function of mechanical context
The brain as command center for bodily movement was too simple an idea, thought the Russian physiologist Nicolas Bernstein some 60 years ago. view more (2006-02-08)
Stem cell research aims to tackle Parkinson's disease
Scientists in Sweden are developing new ways to grow brain cells in the laboratory that could one day be used to treat patients with Parkinson's disease, an international conference of biologists organised by the European Science Foundation (ESF) was told last week. view more (2008-01-21)
Fatty diet during pregnancy makes new cells in fetal brain that cause early onset obesity
A study in rats shows that exposure to a high-fat diet during pregnancy produces permanent changes in the offspring's brain that lead to overeating and obesity early in life, according to new research by Rockefeller University scientists. view more (2008-11-12)
Agent Protects Parkinson's Neurons from Rotenone Toxicity
Researchers at the University at Buffalo affiliated with the New York State Center of Excellence in Bioinformatics and Life Sciences have identified a novel agent that can protect neurons involved in Parkinson's disease from being destroyed by the pesticide rotenone. view more (2006-04-19)
Insight into neural stem cells has implications for designing therapies
Scientists have discovered that adult neural stem cells, which exist in the brain throughout life, are not a single, homogeneous group. view more (2007-07-09)
Worms control lifespan at high temperatures, UCSF study finds
The common research worm, C. elegans, is able to use heat-sensing nerve cells to not only regulate its response to hotter environments, but also to control the pace of its aging as a result of that heat, according to new research at the University of California, San Francisco. view more (2009-04-17)
Caltech researchers pinpoint neurons that control obesity in fruit flies
A team of scientists from the California Institute of Technology (Caltech) have pinpointed two groups of neurons in fruit fly brains that have the ability to sense and manipulate the fly's fat stores in much the same way as do neurons in the mammalian brain. view more (2009-08-19)
MIT researchers watch brain in action
For the first time, scientists have been able to watch neurons within the brain of a living animal change in response to experience. view more (2006-07-31)
Neurons find their place in the developing nervous system with the help of a sticky molecule
The brain, that exquisite network of billions of communicating cells, starts to take form with the genesis of nerve cells. Most newborn nerve cells, also called neurons, must travel from their birthplace to the position they will occupy in the adult brain. view more (2006-04-26)
Blood flow in brain takes a twist, affecting views of Alzheimer's
New findings that long-overlooked brain cells play an important role in regulating blood flow in the brain call into question one of the basic assumptions underlying today's most sophisticated brain imaging techniques and could open a new frontier when it comes to understanding Alzheimer's disease. view more (2006-01-06)
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