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Gene therapy shows promise in model of Parkinson's disease
Scientists at the Ecole Polytechnique Federale de Lausanne (EPFL) in Lausanne, Switzerland, have conducted novel experiments that might one day lead to gene therapy treatment options for patients with Parkinson's disease. In research published this week in the Proceedings of the National Academy of... view more (2004-11-24)

Standing up to paraplegia with gene therapy
Elena Rugarli and colleagues from the National Neurological Institute in Milan have used gene therapy to save sensory and skeletal muscle nerve fibers from degeneration in mice with hereditary spastic paraplegia (HSP).   view more (2005-12-16)

Mad cow protein aids creation of brain cells
Few conditions are more detrimental to human brains than the one popularly referred to as mad cow disease.   view more (2006-02-14)

Overactive nerves in head and neck may account for 'ringing in the ears'
Do your ears ring after a loud concert" Nerves that sense touch in your face and neck may be behind the racket in your brain, University of Michigan researchers say.   view more (2008-01-11)

Picking apart how neurons learn
Johns Hopkins researchers have used mouse mutants to define critical steps involved in learning basic motor skills. The study focuses on the behavior of two proteins and the specific steps they take to control a neuron's ability to learn by adapting to signals from other nerve cells.   view more (2006-03-30)

Neuronal regulators offer potential targets for cancer
Being too brainy can be a bad thing in a junior high cafeteria, where the social hierarchy favors other traits. "Braininess" also causes problems for cells.   view more (2008-03-20)

Memory experts show sleeping rats may have visual dreams
Memories of our life stories may be reinforced while we sleep, MIT researchers report Dec. 17 in the advance online edition of Nature Neuroscience.   view more (2006-12-19)

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway
Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.   view more (2008-01-18)

Amateur boxing linked to brain cell injury
A study of 14 Swedish amateur boxers suggests that they have higher levels of certain chemicals in their cerebrospinal fluid in the days following a bout, indicating injuries to neurons and other cells important to brain function.   view more (2006-09-12)

Alzheimer's disease as a case of brake failure?
Rutgers researcher Karl Herrup and colleagues at Case Western Reserve University have discovered that a protein that suppresses cell division in brain cells effectively "puts the brakes" on the dementia that comes with Alzheimer's disease (AD). When the brakes fail, dementia results.   view more (2008-06-25)

3-substituted indolones as novel therapeutic compounds for neurodegenerative conditions
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), disrupt the quality of life for patients, put a tremendous burden on family caregivers, and cost society billions of dollars annually.   view more (2008-10-29)

New Research Shows Why Too Much Memory May Be a Bad Thing
New research from Columbia University Medical Center may explain why people who are able to easily and accurately recall historical dates or long-ago events, may have a harder time with word recall or remembering the day's current events. They may have too much memory - making it harder to filter... view more (2007-03-30)

'Thirst for knowledge' may be opium craving
Neuroscientists have proposed a simple explanation for the pleasure of grasping a new concept: The brain is getting its fix.   view more (2006-06-21)

Potential new treatment strategy for Alzheimer's disease and other brain and spinal cord damage
A study led by researchers at the San Francisco VA Medical Center and the University of North Carolina, Chapel Hill has identified several new compounds that could play a role in preventing or treating Alzheimer's disease and other degenerative conditions of the nervous system.   view more (2006-05-19)

Researchers look to the brain to explain gender differences in sleep apnea
The neural pathways between two areas of the brain that control the tongue - and their interactions with each other - may hold the key as to why men suffer sleep apnea much more than women.   view more (2006-04-04)

Study suggests nicotine addiction might be controlled by influencing brain mechanisms
There is a clear link between GABA - a chemical substance of the central nervous system that inhibits neurons in the brain - and nicotine dependence, according to a study presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting.   view more (2007-12-10)

Quicker and easier rehabilitation following a stroke
By artificially vibrating certain muscle parts, the brain areas and neuronal pathways responsible for movement can be trained. This has the potential to help stroke patients recover their mobility more quickly. These are the results of PhD research by Maarten Steyvers of the Department of... view more (2004-06-11)

Rutgers Scientists Discover Brain Cell Development Process Implicated in Mental Retardation, Finding May Lead to New Drug Therapies
Scientists at Rutgers, The State University of New Jersey, have discovered a biological process in brain cell development that may help explain some causes of mental retardation. This understanding may one day help other researchers develop therapies that can reduce specific forms of retardation.   view more (2007-08-01)

Why our shifty eyes don't drive us crazy
Our eyes are constantly making saccades, or little jumps. Yet the world appears to us as a smooth whole. Somehow, the brain's visual system "knows" where the eyes are about to move and is able to adjust for that movement.   view more (2006-11-09)

Neurons grown from embryonic stem cells restore function in paralyzed rats
For the first time, researchers have enticed transplants of embryonic stem cell-derived motor neurons in the spinal cord to connect with muscles and partially restore function in paralyzed animals.   view more (2006-06-21)

MIT researcher presents new view of how the cortex forms
A leading neuroscientist at MIT and one from the University of California at San Francisco (UCSF) report in the Nov. 4 special issue of Science dedicated to the brain that the controversy is over: The "protomap" and "protocortex" theories of brain development are dead.   view more (2005-11-14)

Change in neurons' responsiveness marks newly formed sensory associations during learning
During our waking hours, our brains are inundated with sensory information that shifts from one moment to the next.   view more (2005-11-08)

Prozac improves learning and memory in fatal brain disease
Howard Florey Institute scientists in Melbourne have found that fluoxetine (commonly marketed as Prozac¬Æ) not only improves depression in Huntington's disease, but also improves learning and memory.   view more (2005-10-07)

Membrane fusion at the synapse: Janus faced synaptotagmin-1 helps to keep the fast pace
Imagine a bathtub with two soap bubbles colliding but never fusing. Then you add detergent, and the surface of the water goes flat as the walls of the bubbles collapse and merge.   view more (2008-10-30)

A 'traffic light' for neurons means 'go' for improving brain research
Every thought, feeling and action originates from the electrical signals emitted by diverse brain cells enmeshed in a tangle of circuits. At this fundamental level, scientists struggle to explain the mind.   view more (2007-04-05)
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