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Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments
UC Irvine School of Medicine researchers have discovered how new neurons born from endogenous neural stem cells are sent to regions of the brain where they can replace old and dying cells, a finding that suggests how stem cell therapies can be specifically targeted to brain regions affected by neurodegenerative diseases or by stroke. view more (2005-06-24)
"Booster rocket" malfunction implicated in Huntington's disease
CNRS and Inserm research scientists at the Institut Curie have shed new light on the function of huntingtin, the protein whose mutation underlies Huntington's disease. This neurodegenerative disease, like Alzheimer's or Parkinson's, is characterized by the abnormal death of certain neurons. The scientists have discovered that huntingtin, like a... view more... (2004-07-07)
Enzyme may be a key to Alzheimer's-related cell death
A Purdue University researcher has discovered that the amount of an enzyme present in neurons can affect the mechanism thought to cause cell death in Alzheimer's disease patients and may have applications for other diseases such as stroke and heart attack. view more (2009-10-08)
Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al. view more (2008-10-13)
Astrocytes and synaptic plasticity
By mopping up excess neurotrophic factor from neuronal synapses, astrocytes may finely tune synaptic transmission to affect processes such as learning and memory, say Bergami et al. view more (2008-10-14)
Dynamic molecular mechanism to keep brain activity stable
In the brain, many types of synaptic proteins are spatio-temporally regulated to maintain synaptic activity at a constant level. view more (2009-07-13)
Smell experience during critical period alters brain
Unlike the circuitry of the visual system, that of the olfactory system was thought to be hardwired: Once the neurons had formed, no amount of sensory input could change their arrangement. view more (2007-12-06)
Autistic brain has fewer neurons for processing emotion
For the first time, research has shown that the autistic brain has fewer neurons in an area related to emotion and social behavior, according to a new study published in the July 19 issue of The Journal of Neuroscience. view more (2006-07-20)
Killer carbs -- Monash scientist finds the key to overeating as we age
A Monash University scientist has discovered key appetite control cells in the human brain degenerate over time, causing increased hunger and potentially weight-gain as we grow older. view more (2008-08-21)
Brain's impaired ability to sense glucose might play role in type 2 diabetes
New findings from studies in mice suggest that defects in the brain's ability to respond to glucose play a role in the development of non-insulin dependent (type 2) diabetes, and that a high-fat diet may contribute to impairing brain cells' ability to regulate glucose throughout the body. view more (2007-08-30)
Researchers get neurons and silicon talking
European researchers have created an interface between mammalian neurons and silicon chips. view more (2006-03-28)
Human stem cells provide a new model for Lou Gehrig's disease
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating condition in which motor neuron degeneration causes progressive loss of movement and muscle tone, leading to death. view more (2009-02-23)
Telling axons where to go - and grow
In a recent study, Dr. Ingolf Bach and colleagues from the University of Massachusetts Medical School, Worcester and the University of Hamburg (Germany) describe a novel role for the ubiquitin/proteosome protein degradation pathway in the regulation of local actin dynamics in neurons. view more (2005-10-03)
Mice use specialized neurons to detect carbon dioxide in the air
For mice, carbon dioxide often means danger - too many animals breathing in too small a space or a hungry predator exhaling nearby. view more (2007-08-17)
Penn researchers engineer first system of human nerve-cell tissue
Researchers at the University of Pennsylvania School of Medicine have demonstrated that living human nerve cells can be engineered into a network that could one day be used for transplants to repair damaged to the nervous system. They report their findings in the February issue of the Journal of Neurosurgery. view more (2008-02-27)
How mirror neurons allow us to learn and socialize by going through the motions in the head
The old adage that we can only learn how to do something by trying it ourselves may have to be revised in the light of recent discoveries in neuroscience. view more (2008-12-19)
Molecular structure reveals how botulinum toxin attaches to nerve cells
Botulism is a life-threatening disease caused by exposure to botulinum neurotoxins, which are among the most potent toxins known. These neurotoxins are produced by Clostridium botulinum, a bacterium found in soil and food. view more (2006-12-14)
Huntington's disease study shows animal models on target
An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington's Disease (HD) closely resembles that of human HD patients. view more (2007-08-01)
Matrix fragments trigger fatal excitement
Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org). view more (2008-12-30)
Tracking the memory trace
Memory formation follows a dynamic pattern, allowing for retrieval from different areas of the brain, depending on when an organism needs to remember, said a researcher at Baylor College of Medicine. view more (2005-12-05)
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