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Dissecting the machinery of nicotine's reward
Understanding what makes people crave the high of nicotine is a key to developing treatment for this highly addictive drug. And that understanding involves tracing the neural machinery by which nicotine switches on the brain's reward machinery.   view more (2006-06-15)

Dying of excitement
For neurons, overexcitement is deadly. To avoid this, brain cells must sop up unneeded neurotransmitters from the synapse through membrane-bound transporters. If these transporters fail, neurons and other brain cells get excited to death- a phenomenon that may contribute to brain damage during... view more (2006-03-06)

How seizures progress to epilepsy in the young
A major mystery in epilepsy research has been why infants are more prone to seizures than adults and how those seizures progress to chronic epilepsy.   view more (2005-12-08)

Animal model of Parkinson's disease reveals striking sensitivity to common environmental toxins
In findings that support a relationship between agricultural chemicals and Parkinson's disease, two groups of researchers have found new evidence that loss of DJ-1, a gene known to be linked to inherited Parkinson's disease, leads to striking sensitivity to the herbicide paraquat and the... view more (2005-09-07)

Zinc plays important role in brain circuitry
To the multitude of substances that regulate neuronal signaling in the brain and spinal cord add a new key player: zinc. By engineering a mouse with a mutation affecting a neuronal zinc target, researchers have demonstrated a central role for zinc in modulating signaling among the neurons.   view more (2006-11-27)

Limiting stroke damage is focus of study
Brain damage that occurs even days after a stroke, increasing stroke size and devastation, is the focus of researchers trying to identify new treatments.   view more (2007-05-31)

Streamlining brain signals for speed and efficacy
Life exists at the edge of chaos, where small changes can have striking and unanticipated effects, and major stimuli may go unheard.   view more (2008-10-23)

New Study Shows that Fetal Cells Transplanted into the Brain to Treat Parkinson's Disease May Not Function Long Term
Neurons grafted into the brain of a patient with Parkinson's disease fourteen years ago have developed Lewy body pathology, the defining pathology for the disease, according to research by Jeffrey H. Kordower, PhD, and associates and published in the April 6 issue of Nature Medicine.   view more (2008-04-07)

Study links Alzheimer's disease to abnormal cell division
A new study in mice suggests that Alzheimer's disease (AD) may be triggered when adult neurons try to divide. The finding helps researchers understand what goes wrong in the disease and may lead to new ways of treating it.   view more (2006-01-18)

Salk research suggests the existence of specialized neurons that distinguish swagger from sway
It doesn't take John Wayne's deliberate, pigeon-toed swagger or Marilyn Monroe's famously wiggly sway to judge a person's gender based on the way they move.   view more (2006-05-25)

Lend me your ears -- and the world will sound very different
Recognising people, objects or animals by the sound they make is an important survival skill and something most of us take for granted. But very similar objects can physically make very dissimilar sounds and we are able to pick up subtle clues about the identity and source of the sound.   view more (2008-01-14)

Alcoholism may cause decreased density of neurons in the orbitofrontal cortex
Previous research has shown that alcoholism can cause damage to certain brain regions, including reduced metabolism, blood flow and tissue volume, as well as a reduced density of neurons and glial cells.   view more (2006-10-25)

Carnegie Mellon study reveals that odor discrimination is linked to the timing at which neurons fire
Timing is everything. For a mouse trying to discriminate between the scent of a tasty treat and the scent of the neighborhood cat, timing could mean life or death   view more (2006-11-08)

Rare genetic disorder gives clues to autism, epilepsy, mental retardation
A rare genetic disorder called tuberous sclerosis complex (TSC) is yielding insight into a possible cause of some neurodevelopmental disorders: structural abnormalities in neurons, or brain cells.   view more (2008-09-24)

Mediator in communication between neurons and muscle cells found
A missing piece of the puzzle of how neurons and muscle cells establish lifelong communication has been found by researchers who suspect this piece may be mutated and/or attacked in muscular dystrophy.   view more (2008-10-23)

Genetic tags reveal secrets of memories' staying power in mice
A better understanding of how memory works is emerging from a newfound ability to link a learning experience in a mouse to consequent changes in the inner workings of its neurons.   view more (2008-02-22)

Neurons hard wired to tell left from right
It's well known that the left and right sides of the brain differ in many animal species and this is thought to influence cognitive performance and social behaviour. For instance, in humans, the left half of the brain is concerned with language processing whereas the right side is better at... view more (2008-03-31)

Cancer-causing protein may heal damaged spinal cord and brain cells
Cancer researchers at Columbia University Medical Center have found that a protein known for driving the growth of cancer also plays a surprising role in restoring the ability of neurons to regenerate, making it an important target for addressing spinal cord damage or neurological diseases like... view more (2006-06-29)

Researchers develop marker that identifies energy-producing centers in nerve cells
A protein that causes coral to glow is helping researchers at the University of Maryland School of Medicine to light up brain cells that are critical for the proper functioning of the central nervous system.   view more (2007-02-02)

Most important actors in the growth process of neurons identified
Defects in the growth process of our neurons often underlie brain or nerve diseases, such as Alzheimer's disease or multiple sclerosis.   view more (2006-10-12)

Columbia University researchers discover on-off switch for chronic pain
Chronic pain affects approximately 48 million people in the U.S. and current medications are either largely ineffective or have serious side effects.   view more (2006-07-20)

Eating and body weight regulated by specific neurons
Researchers at Yale School of Medicine provide direct evidence that two parts of a neuronal system, one that promotes eating and another that suppresses eating, are critical for the acute regulation of eating and body weight.   view more (2005-09-14)

Good news for the medical marijuana movement: pot proliferates brain cells and boosts mood
Most drugs of abuse decrease the generation of new neurons in the brain, but the effects of marijuana on this process, called neurogenesis, had not been clear.   view more (2005-10-14)

Study suggests new treatments for Huntington's disease
Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington's disease causes neurodegeneration.   view more (2008-01-10)

Researchers identify a gene responsible for cases of Lou Gehrig's disease
A team of Canadian and French researchers has identified a novel gene responsible for a significant fraction of ALS (sporadic amyotrophic lateral sclerosis) cases. ALS is commonly referred to as Lou Gehrig's disease, an incurable neuromuscular disorder that affects motor neurons and leads to... view more (2008-04-01)
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