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Switching to new anti-bacterial targets: Riboswitches
The recently emerged field of bacterial riboswitches may be a good hunting ground for effective targets against bacterial infection, according to a report by Yale researchers in the journal Chemistry and Biology. view more (2005-12-19)
U of M identifies cell line that is resistant to retroviruses, including HIV
Researchers at the University of Minnesota have identified a protein that enables viruses such as HIV to infect cells and spread through the body. view more (2006-10-18)
Study shows risk of acute pancreatitis low with statins
New research reveals that while cholesterol-lowering drugs do increase the risk of painful inflammation of the pancreas, the side effect is relatively rare, according to Sonal Singh, M.D., from Wake Forest University School of Medicine, and colleagues. view more (2007-01-02)
Compound has potential for new class of AIDS drugs
Researchers have developed what they believe is the first new mechanism in nearly 20 years for inhibiting a common target used to treat all HIV patients, which could eventually lead to a new class of AIDS drugs. view more (2008-05-15)
New research provides hope for childhood cancer sufferers
Scientists investigating drug therapies for children with Acute Lymphoblastic Leukaemia (ALL) have presented new data demonstrating for the very first time that a small molecule called ABT-737 can increase the effectiveness of standard therapies. view more (2007-07-17)
Impotency drugs may be associated with increased risk of optic nerve damage
Viagra and Cialis, the drugs used to treat impotency, may be associated with an increased risk of optic nerve damage in men with a history of heart attack or high blood pressure, suggests a small study in the British Journal of Ophthalmology. view more (2006-01-17)
Quicker, Better Drugs To Tackle Diseases
Applications open for £3m fund for chemicals industry Groundbreaking treatments of killer diseases could be made available to patients more quickly after cures have been discovered, under projects to share up to £3m of new funding, the Government announced today. The chemicals and pharmaceutical industry are expected to benefit from... view more... (2001-07-31)
Looking beyond the drug receptor for clues to drug effectiveness
Antipsychotic drugs that are widely used to treat schizophrenia and other problems may not work as scientists have assumed, according to findings from Duke University Medical Center researchers that could lead to changes in how these drugs are developed and prescribed. view more (2008-08-26)
Dual treatment of incontinence and dementia associated with functional decline
Older nursing home residents who took medications for dementia and incontinence at the same time had a 50 percent faster decline in function than those who were being treated only for dementia, according to a study from researchers at Wake Forest University School of Medicine and colleagues. view more (2008-05-01)
Slow-growing TB bacteria point the way to new drug development
The discovery of a large number of slow-growing Mycobacterium tuberculosis bacteria, which cause tuberculosis (TB), in the lungs of TB patients could be an important step forward in the design of new anti-TB drugs. view more (2009-03-30)
Chemosensitivity of cancer cells depends on their protein dependency
Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. The study will be published online October 26, 2009 and in the November 2, 2009 print issue of the Journal of Cell Biology (JCB). view more (2009-10-26)
Many patients still missing out on drugs to cut heart attacks and stroke
Many patients who need statins to cut their risk of heart attacks and stroke are missing out, particularly the elderly, finds research in Heart. view more (2003-03-17)
Teenagers with one parent at risk of substance abuse
Teenagers from some single parent families are most likely to experiment with drugs, cigarettes and alcohol and experience some mental health issues. view more (2004-08-24)
Anti-rejection drug may increase risk of diabetes after kidney transplant
For patients undergoing kidney transplantation, treatment with the anti-rejection drug sirolimus may lead to an increased risk of diabetes, reports a study in the July Journal of the American Society of Nephrology (JASN). view more (2008-05-23)
Study suggests some drug resistance to influenza B medications
Use of certain common antiviral drugs during a recent influenza B epidemic in Japan showed the development of viruses with partial resistance to the drugs, according to a study in the April 4 issue of JAMA. view more (2007-04-04)
Nanoparticle 'Smart Bomb' Targets Drug Delivery to Cancer Cells
Researchers at North Carolina State University have successfully modified a common plant virus to deliver drugs only to specific cells inside the human body, without affecting surrounding tissue. view more (2009-02-13)
Boosting social skills reduces teenage drug use and addiction
School-based programmes that develop individual young people's social skills are the best way to reduce drug use. view more (2005-04-14)
Our brains make their own marijuana: We're all pot heads deep inside
U.S. and Brazilian scientists have just proven that one of Bob Dylan's most famous lines--"everybody must get stoned"-- is correct. view more (2009-04-21)
Commonly used ulcer drugs may offer treatment potential in Alzheimer's disease
In a new study, published in the May issue of Elsevier's Experimental Neurology, scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug. view more (2009-04-22)
Not all 'drug-related deaths' are 'drug-related'
UK estimates of 'drug-related deaths' (DRDs) include mortalities of drug abusers and non-drug abusers. So these figures may not be the best way of monitoring the performance of Drug and Alcohol Action Teams. view more (2007-08-09)
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